Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA. (Q30837863)

19 October 2017

Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA. (English)

1 reference

19 October 2017

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7

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Antoni Ribas

8

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Mark E. Davis

9

object named as

Mark E Davis

1 reference

19 October 2017

5

Dean Lim

1 reference

19 October 2017

Jonathan E Zuckerman

1

1 reference

19 October 2017

Ismael Gritli

2

1 reference

19 October 2017

Anthony Tolcher

3

1 reference

19 October 2017

Jeremy D Heidel

4

1 reference

19 October 2017

Robert Morgan

6

1 reference

19 October 2017

Yun Yen

10

1 reference

19 October 2017

language of work or name

English

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publication date

21 July 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 October 2017

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19 October 2017

111

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19 October 2017

31

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19 October 2017

11449-11454

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Delivery materials for siRNA therapeutics

19 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Correlating preclinical animal studies and human clinical trials of a multifunctional, polymeric nanoparticle

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Systemic delivery of siRNA nanoparticles targeting RRM2 suppresses head and neck tumor growth.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Atelocollagen-mediated systemic delivery prevents immunostimulatory adverse effects of siRNA in mammals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Misinterpreting the therapeutic effects of small interfering RNA caused by immune stimulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Dose translation from animal to human studies revisited

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Ribonucleotide reductase inhibitors and future drug design

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Development of an ultrasensitive noncompetitive hybridization-ligation enzyme-linked immunosorbent assay for the determination of phosphorothioate oligodeoxynucleotide in plasma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Transferrin receptors in human tissues: their distribution and possible clinical relevance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Comparison of histamine release induced by synthetic polycations with that by compound 48/80 from rat mast cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128111

Allometric scaling of pegylated liposomal anticancer drugs.

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1411393111

Lack of interferon response in animals to naked siRNAs

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25049380

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pitfalling in nanomedical targeting of melanoma: a 'clinical' case of misdelivered RNAi

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25049380

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1411393111

1 reference

19 October 2017

0 references

1 reference

19 October 2017

1 reference