The Dynamics and Turnover of Tau Aggregates in Cultured Cells: INSIGHTS INTO THERAPIES FOR TAUOPATHIES. (Q30780758)

18 August 2017

The Dynamics and Turnover of Tau Aggregates in Cultured Cells: INSIGHTS INTO THERAPIES FOR TAUOPATHIES. (English)

1 reference

18 August 2017

Jing L Guo

1

1 reference

18 August 2017

Arjan Buist

2

1 reference

18 August 2017

Alberto Soares

3

1 reference

18 August 2017

Kathleen Callaerts

4

1 reference

18 August 2017

Sara Calafate

5

1 reference

18 August 2017

Frederik Stevenaert

6

1 reference

18 August 2017

Joshua P Daniels

7

1 reference

18 August 2017

Bryan E Zoll

8

1 reference

18 August 2017

Alex Crowe

9

1 reference

18 August 2017

Kurt R Brunden

10

1 reference

18 August 2017

Diederik Moechars

11

1 reference

18 August 2017

Virginia M Y Lee

12

1 reference

18 August 2017

language of work or name

English

0 references

publication date

18 April 2016

1 reference

18 August 2017

19

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

18 August 2017

291

1 reference

18 August 2017

25

1 reference

18 August 2017

13175-13193

1 reference

describes a project that uses

18 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4933232/fullTextXML

inferred from PubMed Central ID database lookup

cites work

A mechanistic model of tau amyloid aggregation based on direct observation of oligomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Tau clearance mechanisms and their possible role in the pathogenesis of Alzheimer disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Reversal of neurofibrillary tangles and tau-associated phenotype in the rTgTauEC model of early Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Lewy body-like α-synuclein aggregates resist degradation and impair macroautophagy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Characteristics of progressive supranuclear palsy presenting with corticobasal syndrome: a cortical variant

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Direct observation of the interconversion of normal and toxic forms of α-synuclein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Neuropathological features of corticobasal degeneration presenting as corticobasal syndrome or Richardson syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Regulation of mammalian autophagy in physiology and pathophysiology.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Mechanisms underlying inflammation in neurodegeneration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Methods in mammalian autophagy research

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

An analytical solution to the kinetics of breakable filament assembly

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Specificity and regulation of casein kinase-mediated phosphorylation of alpha-synuclein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

The roles of intracellular protein-degradation pathways in neurodegeneration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Pathological heterogeneity of frontotemporal lobar degeneration with ubiquitin-positive inclusions delineated by ubiquitin immunohistochemistry and novel monoclonal antibodies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Molecular recycling within amyloid fibrils

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Tau suppression in a neurodegenerative mouse model improves memory function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Neurodegenerative tauopathies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Novel cathepsin D inhibitors block the formation of hyperphosphorylated tau fragments in hippocampus.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Immunocytochemical co-localization of the proteasome in ubiquitinated structures in neurodegenerative diseases and the elderly.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Ubiquitin-protein conjugates in Alzheimer's lesions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Multicatalytic proteinase is present in Lewy bodies and neurofibrillary tangles in diffuse Lewy body disease brains.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

A protein factor essential for microtubule assembly

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

20 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.712083

Autophagic degradation of tau in primary neurons and its enhancement by trehalose.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.712083

In search of an "autophagomometer".

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.712083

Amplification of Tau fibrils from minute quantities of seeds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.712083

'Prion-like' propagation of mouse and human tau aggregates in an inducible mouse model of tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.712083

Assembly of A beta amyloid protofibrils: an in vitro model for a possible early event in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.712083

Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.712083

Heterogeneity of ubiquitin immunoreactivity in neurofibrillary tangles of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.712083

Alzheimer's lesions labelled by anti-ubiquitin antibodies: comparison with other staining techniques. A study of 15 cases with graded intellectual status in ageing and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.712083

Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.712083

Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933232

Impaired proteasome function in Alzheimer's disease

25 November 2018

1 reference

12 December 2020

Study of the disassembly-assembly process of alpha-synuclein fibrils by in situ atomic force microscopy

1 reference

12 December 2020

The dynamic nature of amyloid beta (1-40) aggregation

1 reference

12 December 2020

Characterization of two VQIXXK motifs for tau fibrillization in vitro

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M115.712083

1 reference

18 August 2017

1 reference

18 August 2017

1 reference