Huntingtin differentially regulates the axonal transport of a sub-set of Rab-containing vesicles in vivo. (Q30683859)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450517%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

title

Huntingtin differentially regulates the axonal transport of a sub-set of Rab-containing vesicles in vivo (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450517%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

6

1 reference

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26 February 2020

author name string

Joseph A White

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450517%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Eric Anderson

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450517%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Katherine Zimmerman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450517%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Kan Hong Zheng

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450517%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Roza Rouhani

5

1 reference

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26 February 2020

publication date

8 October 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450517%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

published in

Human Molecular Genetics

1 reference

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26 February 2020

volume

24

1 reference

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26 February 2020

issue

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450517%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

page(s)

7182-7195

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450517%20AND%20SRC:MED&resulttype=core&format=json

Disruption of axonal transport perturbs bone morphogenetic protein (BMP)--signaling and contributes to synaptic abnormalities in two neurodegenerative diseases

26 February 2020

cites work

1 reference

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Rab18 and a Rab18 GEF complex are required for normal ER structure

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Rab-mediated trafficking role in neurite formation

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The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation

28 July 2018

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Modeling Huntington disease in Drosophila: Insights into axonal transport defects and modifiers of toxicity.

28 July 2018

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Presenilin controls kinesin-1 and dynein function during APP-vesicle transport in vivo

28 July 2018

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Defective axonal transport of Rab7 GTPase results in dysregulated trophic signaling.

28 July 2018

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Huntingtin's function in axonal transport is conserved in Drosophila melanogaster

28 July 2018

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Vesicular glycolysis provides on-board energy for fast axonal transport

28 July 2018

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Discovery of Novel DENN Proteins: Implications for the Evolution of Eukaryotic Intracellular Membrane Structures and Human Disease

28 July 2018

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Reticulon-like-1, the Drosophila orthologue of the hereditary spastic paraplegia gene reticulon 2, is required for organization of endoplasmic reticulum and of distal motor axons

28 July 2018

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Rab11 rescues synaptic dysfunction and behavioural deficits in a Drosophila model of Huntington's disease

28 July 2018

1 reference

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Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila

28 July 2018

1 reference

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Apolipoprotein E promotes β-amyloid trafficking and degradation by modulating microglial cholesterol levels

28 July 2018

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Systematic discovery of Rab GTPases with synaptic functions in Drosophila

28 July 2018

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Rab GTPases and microtubule motors

28 July 2018

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Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes

28 July 2018

1 reference

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In vivo visualization of synaptic vesicles within Drosophila larval segmental axons

28 July 2018

1 reference

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Aberrant Rab11-dependent trafficking of the neuronal glutamate transporter EAAC1 causes oxidative stress and cell death in Huntington's disease

28 July 2018

1 reference

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FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport

28 July 2018

1 reference

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Mutant huntingtin impairs vesicle formation from recycling endosomes by interfering with Rab11 activity

28 July 2018

1 reference

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Rab GTPases as coordinators of vesicle traffic

28 July 2018

1 reference

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The Rip11/Rab11-FIP5 and kinesin II complex regulates endocytic protein recycling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4664163

Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4664163

Rab4 and Rab11 coordinately regulate the recycling of angiotensin II type I receptor as demonstrated by fluorescence resonance energy transfer microscopy

28 July 2018

1 reference

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Functional characterization of Rab7 mutant proteins associated with Charcot-Marie-Tooth type 2B disease

28 July 2018

1 reference

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Huntingtin facilitates dynein/dynactin-mediated vesicle transport.

28 July 2018

1 reference

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Thirty-one flavors of Drosophila rab proteins.

28 July 2018

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Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathway

28 July 2018

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Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease

28 July 2018

1 reference

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Purification and functional properties of a Rab8-specific GEF (Rabin3) in action remodeling and polarized transport

28 July 2018

1 reference

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Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons

28 July 2018

1 reference

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Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

28 July 2018

1 reference

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Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

28 July 2018

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Rab14 is involved in membrane trafficking between the Golgi complex and endosomes

28 July 2018

1 reference

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Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease.

28 July 2018

1 reference

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The mechanisms of vesicle budding and fusion

28 July 2018

1 reference

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Human VPS34 and p150 are Rab7 Interacting Partners

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4664163

Dual prenylation is required for Rab protein localization and function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4664163

The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4664163

Role of Rab3 GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction

28 July 2018

1 reference

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Rab proteins as membrane organizers

28 July 2018

1 reference

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A Rab11/Rip11 protein complex regulates apical membrane trafficking via recycling endosomes

28 July 2018

1 reference

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FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4664163

Rab7: a key to lysosome biogenesis

28 July 2018

1 reference

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A human HAP1 homologue. Cloning, expression, and interaction with huntingtin

28 July 2018

1 reference

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Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4664163

A GDP-bound of rab1 inhibits protein export from the endoplasmic reticulum and transport between Golgi compartments

28 July 2018

1 reference

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Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

28 July 2018

1 reference

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Widespread expression of Huntington's disease gene (IT15) protein product

28 July 2018

1 reference

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A huntingtin-associated protein enriched in brain with implications for pathology

28 July 2018

1 reference

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Do GTPases direct membrane traffic in secretion?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4664163

The GTP-binding protein Ypt1 is required for transport in vitro: the Golgi apparatus is defective in ypt1 mutants

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4664163

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

28 July 2018

1 reference

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GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4664163

Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys

28 July 2018

1 reference

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Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila

28 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV415

In-vivo evidence for the disruption of Rab11 vesicle transport by loss of huntingtin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV415

The Connecdenn DENN domain: a GEF for Rab35 mediating cargo-specific exit from early endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV415

Rab35 regulates Arf6 activity through centaurin-β2 (ACAP2) during neurite outgrowth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV415

Rab10 GTPase regulates ER dynamics and morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV415

Blue light-dependent interaction of CRY2 with SPA1 regulates COP1 activity and floral initiation in Arabidopsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV415

The neuronal endoplasmic reticulum: Its cytochemistry and contribution to the endomembrane system. II. Axons and terminals

21 January 2018

1 reference

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Mutant huntingtin inhibits clathrin-independent endocytosis and causes accumulation of cholesterol in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV415

LC3 binding to the scaffolding protein JIP1 regulates processive dynein-driven transport of autophagosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV415

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV415

Dendritic spine loss and neurodegeneration is rescued by Rab11 in models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV415

The recycling endosome and its role in neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV415

Endogenous GSK-3/shaggy regulates bidirectional axonal transport of the amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV415

Rab6 is a modulator of the unfolded protein response: implications for Alzheimer's disease.

21 January 2018

1 reference

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Vesicle trafficking: a Rab family profile

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4664163

Rough surfaced smooth endoplasmic reticulum in rat and mouse cerebellar Purkinje cells visualized by quick-freezing techniques.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4664163

Role of Rab5 in the Recruitment of hVps34/p150 to the Early Endosome

25 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26450517

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Golgi fragmentation is Rab and SNARE dependent in cellular models of Parkinson's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26450517

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDV415

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450517%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450517%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

PubMed publication ID

26450517

1 reference