How does the apolipoprotein E genotype modulate the brain in aging and in Alzheimer's disease? A review of neuroimaging studies (Q30599020)

25 June 2017

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title

How does the apolipoprotein E genotype modulate the brain in aging and in Alzheimer's disease? A review of neuroimaging studies (English)

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25 June 2017

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4

Soininen H

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25 June 2017

Lehtovirta M

1

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PubMed ID

10867214

25 June 2017

Laakso MP

series ordinal

2

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PubMed ID

10867214

25 June 2017

Frisoni GB

series ordinal

3

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25 June 2017

1 March 2000

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25 June 2017

Neurobiology of Aging

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25 June 2017

21

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25 June 2017

2

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25 June 2017

293-300

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Are genetic factors important in the aetiology of leukoaraiosis? Results from a memory clinic population.

25 June 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Synaptic pathology in Alzheimer's disease: relation to severity of dementia, but not to senile plaques, neurofibrillary tangles, or the ApoE4 allele.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

White matter lesions in Alzheimer patients are influenced by apolipoprotein E genotype.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Longitudinal changes in cognitive function and regional cerebral function in Alzheimer's disease: a SPECT blood flow study.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

No difference in cerebral glucose metabolism in patients with Alzheimer disease and differing apolipoprotein E genotypes.

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https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Accelerated decline in apolipoprotein E-epsilon4 homozygotes with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Apolipoprotein E genotype and rate of decline in probable Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Presymptomatic hippocampal atrophy in Alzheimer's disease. A longitudinal MRI study.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Gene dose of the epsilon 4 allele of apolipoprotein E and disease progression in sporadic late-onset Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Apolipoprotein E genotype and hippocampal asymmetry in Alzheimer's disease: a volumetric MRI study

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https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

APOE-epsilon4 is associated with less frontal and more medial temporal lobe atrophy in AD.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Clinical and pathological correlates of apolipoprotein E ?4 in Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Apolipoprotein E genotype does not influence rates of cognitive decline in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Regional cerebral glucose utilization is modulated by the dosage of apolipoprotein E type 4 allele and alpha1-antichymotrypsin type A allele in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Lack of association of apolipoprotein E epsilon4 allele dose with cerebral glucose metabolism in Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Apolipoprotein E and the neuropathology of dementia.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Rate of medial temporal lobe atrophy in typical aging and Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Hippocampal atrophy and apolipoprotein E genotype are independently associated with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Initiation and propagation stages of beta-amyloid are associated with distinctive apolipoprotein E, age, and gender profiles.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Major decrease in the volume of the entorhinal cortex in patients with Alzheimer's disease carrying the apolipoprotein E epsilon4 allele

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Deficits in cerebral glucose metabolism demonstrated by positron emission tomography in individuals at risk of familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Metabolic alterations in postmortem Alzheimer's disease brain are exaggerated by Apo-E4.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Apolipoprotein E epsilon 4 allele, cognitive decline, and deterioration of everyday performance in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Longitudinal SPECT study in Alzheimer's disease: relation to apolipoprotein E polymorphism

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Volumes of hippocampus, amygdala and frontal lobe in Alzheimer patients with different apolipoprotein E genotypes.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

SPECT and MRI analysis in Alzheimer's disease: relation to apolipoprotein E epsilon 4 allele

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Apolipoprotein E polymorphism influences the cerebral metabolic pattern in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Influence of the apolipoprotein E genotype on amyloid deposition and neurofibrillary tangle formation in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Apolipoprotein E polymorphism influences not only cerebral senile plaque load but also Alzheimer-type neurofibrillary tangle formation

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Astrogliosis and the ApoE genotype. an immunohistochemical study of postmortem human brain tissue.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Apolipoprotein E (apoE) levels in brains from Alzheimer disease patients and controls.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Apolipoprotein E epsilon 4 allele and hippocampal volume in twins with normal cognition.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Apolipoprotein E, Dementia, and Cortical Deposition of β-Amyloid Protein

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Relationship between cognitive and morphological asymmetry in dementia of the Alzheimer type: a CT scan study.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Hippocampal volumes in cognitively normal persons at genetic risk for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Tetrahydroaminoacridine improves the recency effect in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Longitudinal study of cerebral blood flow in Alzheimer's disease using single photon emission tomography

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Probable Alzheimer disease: diagnosis with proton MR spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

A severe loss of choline acetyltransferase in the frontal cortex of Alzheimer patients carrying apolipoprotein epsilon 4 allele

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Increased acetylcholinesterase activity in the CSF of Alzheimer patients carrying apolipoprotein epsilon4 allele.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Decreased hippocampal volume asymmetry on MRIs in nondemented elderly subjects carrying the apolipoprotein E epsilon 4 allele.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Inferior temporal lobe atrophy and APOE genotypes in Alzheimer's disease. X-ray computed tomography, magnetic resonance imaging and Xe-133 SPECT studies.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Reduced size of right hippocampus in 39- to 80-year-old normal subjects carrying the apolipoprotein E epsilon4 allele

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Inheritance of the ApoE epsilon4 allele increases the rate of brain atrophy in dementia patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Absence of an apolipoprotein E epsilon4 allele is associated with increased parietal regional cerebral blood flow asymmetry in Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Specific regional transcription of apolipoprotein E in human brain neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

Temporal progression of hippocampal atrophy and apolipoprotein E gene in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2800%2900120-2

7 January 2021

10.1016/S0197-4580(00)00120-2

Identifiers

DOI

1 reference

25 June 2017

1 reference

PubMed ID

10867214