In vitro cell transformation assays for an integrated, alternative assessment of carcinogenicity: a data-based analysis (Q30576475)

25 June 2017

In vitro cell transformation assays for an integrated, alternative assessment of carcinogenicity: a data-based analysis (English)

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25 June 2017

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Olga Tcheremenskaia

3

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Cecilia Bossa

object named as

Cecilia Bossa

series ordinal

2

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Romualdo Benigni

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1

object named as

Romualdo Benigni

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25 June 2017

6 November 2012

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25 June 2017

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25 June 2017

28

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25 June 2017

1

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25 June 2017

107-116

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The multitude and diversity of environmental carcinogens

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Mechanisms of chemical carcinogenicity and mutagenicity: a review with implications for predictive toxicology

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15 million new cancer cases per year by 2020, says WHO

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Avoided and avoidable risks of cancer

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Cancer incidences in Europe related to mortalities, and ethnohistoric, genetic, and geographic distances

21 January 2018

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Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland

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Carcinogenesis bioassays: study duration and biological relevance.

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Alleged misconceptions' distort perceptions of environmental cancer risks.

21 January 2018

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Doses in rodent cancer studies: sorting fact from fiction

21 January 2018

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Predictive strategies for selecting 379 NCI/NTP chemicals evaluated for carcinogenic potential: scientific and public health impact

21 January 2018

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Scientific concepts, value, and significance of chemical carcinogenesis studies

21 January 2018

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Identification of carcinogenic agents and primary prevention of cancer

21 January 2018

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Historical perspective on the development of the genetic toxicity test battery in the United States

21 January 2018

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Identification of rodent carcinogens and noncarcinogens using genetic toxicity tests: premises, promises, and performance.

21 January 2018

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Structure-activity relationships of chemical mutagens and carcinogens

21 January 2018

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The expanding role of predictive toxicology: an update on the (Q)SAR models for mutagens and carcinogens

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Toward a quantitative comparative toxicology of organic compounds.

21 January 2018

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Using chemical categories to fill data gaps in hazard assessment.

21 January 2018

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Research on early-stage carcinogenesis: are we approaching paradigm instability?

21 January 2018

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Alternatives to the carcinogenicity bioassay for toxicity prediction: are we there yet?

21 January 2018

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Series: 'Current issues in mutagenesis and carcinogenesis.' No. 42. Strategies and philosophies of genotoxicity testing: what is the question?

21 January 2018

1 reference

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Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens III. Appropriate follow-up testing in vivo

21 January 2018

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Current and future application of genetic toxicity assays: the role and value of in vitro mammalian assays

21 January 2018

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Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity

21 January 2018

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Alternatives to the carcinogenicity bioassay: in silico methods, and the in vitro and in vivo mutagenicity assays

21 January 2018

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The new ISSMIC database on in vivo micronucleus and its role in assessing genotoxicity testing strategies.

21 January 2018

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21 January 2018

More Toxin Tests Needed

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Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach

21 January 2018

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Evidence for the progressive nature of neoplastic transformation in vitro

21 January 2018

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IN VITRO CELL TRANSFORMATION WITH CHEMICAL CARCINOGENS.

21 January 2018

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OECD Detailed Review Paper (DRP) number 31 on "Cell Transformation Assays for Detection of Chemical Carcinogens": main results and conclusions

21 January 2018

1 reference

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ECVAM prevalidation study on in vitro cell transformation assays: general outline and conclusions of the study

21 January 2018

1 reference

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Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics

21 January 2018

1 reference

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Alternative strategies for carcinogenicity assessment: an efficient and simplified approach based on in vitro mutagenicity and cell transformation assays.

21 January 2018

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A Bhas 42 cell transformation assay on 98 chemicals: the characteristics and performance for the prediction of chemical carcinogenicity

21 January 2018

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Mechanisms of chemical carcinogenesis

21 January 2018

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Structure alerts for carcinogenicity, and the Salmonella assay system: a novel insight through the chemical relational databases technology.

21 January 2018

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Measuring the accuracy of diagnostic systems

21 January 2018

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Cell transformation assays for prediction of carcinogenic potential: state of the science and future research needs

21 January 2018

1 reference

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The syrian hamster embryo (SHE) cell transformation assay: review of the methods and results

21 January 2018

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Efficient immortalization of primary human cells by p16INK4a-specific short hairpin RNA or Bmi-1, combined with introduction of hTERT.

21 January 2018

1 reference

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21 January 2018

Fibroblasts in cancer

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The tissue organization field theory of cancer: a testable replacement for the somatic mutation theory

21 January 2018

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Morphogens, morphostats, microarchitecture and malignancy

21 January 2018

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Toxicity testing in the 21st century: implications for human health risk assessment

21 January 2018

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Adverse outcome pathways: a conceptual framework to support ecotoxicology research and risk assessment

21 January 2018

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Can cell systems biology rescue drug discovery?

21 January 2018

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Non-genotoxic mechanisms of carcinogenesis: studies of cell transformation and gap junctional intercellular communication.

21 January 2018

1 reference

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Partition coefficients and the structure-activity relation of the anesthetic gases

21 January 2018

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Exploring In Vitro/In Vivo Correlation: Lessons Learned from Analyzing Phase I Results of the US EPA's ToxCast Project

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1093/MUTAGE/GES059

1 reference

25 June 2017

1 reference

PubMed ID

23132285