Possible treatment of end-stage hyperammonemic encephalopathy by inhibition of glutamine synthetase (Q30573369)

15 August 2017

Possible treatment of end-stage hyperammonemic encephalopathy by inhibition of glutamine synthetase (English)

1 reference

15 August 2017

Arthur J L Cooper

1

1 reference

15 August 2017

13 October 2012

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15 August 2017

Metabolic Brain Disease

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15 August 2017

28

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15 August 2017

2

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15 August 2017

119-125

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The role of glutamine synthetase and glutamate dehydrogenase in cerebral ammonia homeostasis

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Pathogenesis of hepatic encephalopathy and brain edema in acute liver failure: role of glutamine redefined

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Neuroimaging in acute liver failure.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Compartmentalized Cerebral Metabolism of [1,6-(13)C]Glucose Determined by in vivo (13)C NMR Spectroscopy at 14.1 T.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Astrocyte glutamine synthetase: importance in hyperammonemic syndromes and potential target for therapy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Hepatic glutamate metabolism: a tale of 2 hepatocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Direct molecular and spectroscopic evidence for increased ammonia removal capacity of skeletal muscle in acute liver failure.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

In vivo (13)C NMR measurement of neurotransmitter glutamate cycling, anaplerosis and TCA cycle flux in rat brain during

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Optimal freezing conditions for cerebral metabolites in rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Freeze-blowing: a new technique for the study of brain in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Identification of L-methionine-S-sulfoximine as the convulsant isomer of methionine sulfoximine

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Biochemistry and physiology of brain ammonia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Cerebral ammonia metabolism in hyperammonemic rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Enzymatic reactions of methionine sulfoximine. Conversion to the corresponding alpha-imino and alpha-keto acids and to alpha-ketobutyrate and methane sulfinimide

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

The metabolic fate of 13N-labeled ammonia in rat brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Correlation of plasma and brain amino acid and putative neurotransmitter alterations during acute hepatic coma in the rat

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Fine structural localization of glutamine synthetase in astrocytes of rat brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Differential inhibition of glutamine and gamma-glutamylcysteine synthetases by alpha-alkyl analogs of methionine sulfoximine that induce convulsions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Chronic inhibition of glutamine synthetase is not associated with impairment of learning and memory in mice

20 June 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9338-2

Glycogen, ammonia and related metabolities in the brain during seizures evoked by methionine sulphoximine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9338-2

Effect of reducing brain glutamine synthesis on metabolic symptoms of hepatic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9338-2

A glutamine synthetase inhibitor increases survival and decreases cytokine response in a mouse model of acute liver failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9338-2

Brain metabolism of 13N-ammonia during acute hepatic encephalopathy in cirrhosis measured by positron emission tomography

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9338-2

Correlation between ammonia levels and the severity of hepatic encephalopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9338-2

Studies on the Mechanism of Glutamine Synthesis; Isolation and Properties of the Enzyme from Sheep Brain*

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9338-2

THE NATURE OF THE INHIBITION IN VITRO OF CEREBRAL GLUTAMINE SYNTHETASE BY THE CONVULSANT, METHIONINE SULFOXIMINE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9338-2

Action of nitrogen trichloride on certain proteins. II. Synthesis of methionine sulphoximine and other sulphoximines.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

EFFECT OF AN INHIBITOR OF GLUTAMINE SYNTHESIS (METHIONINE SULFOXIMINE) ON AMMONIA TOXICITY AND METABOLISM

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Cerebral methylations in epileptogenesis

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566340

Methionine Sulphoximine and some Enzyme Systems involving Glutamine

26 November 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9338-2

Effect of methionine sulfoximine in man

21 January 2018

1 reference

12 December 2020

Metabolic abnormalities and grade of encephalopathy in acute hepatic failure

1 reference

12 December 2020

Dist and canine hysteria; experimental production by treated flour

1 reference

12 December 2020

The relative effect of methionine sulfoximine on different animal species

1 reference

12 December 2020

10.1007/S11011-012-9338-2

Identifiers

DOI

1 reference

PMC publication ID

3566340

Dimensions Publication ID

15 August 2017

0 references

1 reference

PMC publication ID

3566340

15 August 2017

PubMed publication ID

23065027

1 reference

PMC publication ID

3566340