Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer's-like cognitive decline (Q30572684)

21 August 2017

Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer's-like cognitive decline (English)

1 reference

21 August 2017

1 reference

1 reference

1

Kenneth E Bernstein

1 reference

21 August 2017

Maya Koronyo-Hamaoui

15

1 reference

ORCID Public Data File 2021

author name string

Yosef Koronyo

2

1 reference

21 August 2017

Brenda C Salumbides

3

1 reference

21 August 2017

Julia Sheyn

4

1 reference

21 August 2017

Lindsey Pelissier

5

1 reference

21 August 2017

Dahabada H J Lopes

6

1 reference

21 August 2017

Kandarp H Shah

7

1 reference

21 August 2017

Ellen A Bernstein

8

1 reference

21 August 2017

Dieu-Trang Fuchs

9

1 reference

21 August 2017

Jeff J-Y Yu

10

1 reference

21 August 2017

Michael Pham

11

1 reference

21 August 2017

Keith L Black

12

1 reference

21 August 2017

Xiao Z Shen

13

1 reference

21 August 2017

Sebastien Fuchs

14

1 reference

21 August 2017

language of work or name

English

0 references

publication date

1 March 2014

1 reference

21 August 2017

13

1 reference

Journal of Clinical Investigation

inferred from page(s)

published in

1 reference

21 August 2017

124

1 reference

21 August 2017

3

1 reference

21 August 2017

1000-1012

1 reference

describes a project that uses

21 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3934162/fullTextXML

inferred from PubMed Central ID database lookup

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The biphasic role of microglia in Alzheimer's disease

20 June 2018

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Nontraditional roles of angiotensin-converting enzyme

20 June 2018

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The renin-angiotensin system and antihypertensive drugs in Alzheimer's disease: current standing of the angiotensin hypothesis?

20 June 2018

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Proteolytic processing of Alzheimer's β-amyloid precursor protein

20 June 2018

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The carboxypeptidase ACE shapes the MHC class I peptide repertoire

20 June 2018

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β-Adrenergic receptor antagonism prevents anxiety-like behavior and microglial reactivity induced by repeated social defeat

20 June 2018

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Decreased clearance of CNS beta-amyloid in Alzheimer's disease

20 June 2018

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Angiotensin-converting enzyme overexpression in mouse myelomonocytic cells augments resistance to Listeria and methicillin-resistant Staphylococcus aureus

20 June 2018

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Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice

20 June 2018

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Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model

20 June 2018

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Systemic inflammatory cells fight off neurodegenerative disease

20 June 2018

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IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice

20 June 2018

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Mechanisms of mononuclear phagocyte recruitment in Alzheimer's disease

20 June 2018

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Inflammation, microglia, and Alzheimer's disease

20 June 2018

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Angiotensins in Alzheimer's disease - friend or foe?

20 June 2018

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Abeta42-to-Abeta40- and angiotensin-converting activities in different domains of angiotensin-converting enzyme

20 June 2018

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Angiotensins and Alzheimer's disease: a bench to bedside overview

20 June 2018

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Prolonged microglial cell activation and lymphocyte infiltration following experimental herpes encephalitis

20 June 2018

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Targeting beta-amyloid pathology in Alzheimer's disease with Abeta immunotherapy

20 June 2018

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Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

20 June 2018

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Catabolic attacks of membrane-bound angiotensin-converting enzyme on the N-terminal part of species-specific amyloid-beta peptides

20 June 2018

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Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior

20 June 2018

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Phagocytosis of amyloid-beta and inflammation: two faces of innate immunity in Alzheimer's disease

20 June 2018

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Mice with enhanced macrophage angiotensin-converting enzyme are resistant to melanoma.

20 June 2018

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Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid beta-protein metabolism in mouse models of Alzheimer disease

20 June 2018

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Inflammation in Alzheimer disease: driving force, bystander or beneficial response?

20 June 2018

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Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1

20 June 2018

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Neuroprotective properties of the innate immune system and bone marrow stem cells in Alzheimer's disease

20 June 2018

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Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor

20 June 2018

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Large meta-analysis establishes the ACE insertion-deletion polymorphism as a marker of Alzheimer's disease

20 June 2018

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Quantification of the A beta peptide in Alzheimer's plaques by laser dissection microscopy combined with mass spectrometry

20 June 2018

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The microglial phagocytic role with specific plaque types in the Alzheimer disease brain

20 June 2018

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Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

20 June 2018

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Beta-amyloid production, aggregation, and clearance as targets for therapy in Alzheimer's disease

20 June 2018

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Local neuroinflammation and the progression of Alzheimer's disease

20 June 2018

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Quantitative mRNA expression profiling of ACE 2, a novel homologue of angiotensin converting enzyme

20 June 2018

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Inflammation in neurodegenerative disease--a double-edged sword

20 June 2018

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

20 June 2018

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Resident and infiltrating central nervous system APCs regulate the emergence and resolution of experimental autoimmune encephalomyelitis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

The ACE gene and Alzheimer's disease susceptibility

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Neuroinflammation and Alzheimer's disease: critical roles for cytokine/Abeta-induced glial activation, NF-kappaB, and apolipoprotein E.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Inflammation and Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Cell mediators of inflammation in the Alzheimer disease brain

20 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Complement component C1q modulates the phagocytosis of Abeta by microglia

20 June 2018

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Alzheimer's disease as proteolytic disorders: anabolism and catabolism of beta-amyloid

20 June 2018

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Normal and abnormal biology of the beta-amyloid precursor protein

20 June 2018

1 reference

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Transgenic mice demonstrate a testis-specific promoter for angiotensin-converting enzyme.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Control of murine Ly6Chigh monocyte traffic and immunosuppressive activities by atypical chemokine receptor D6

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Egr1 expression is induced following glatiramer acetate immunotherapy in rodent models of glaucoma and Alzheimer's disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Spatial learning and memory impairment and increased locomotion in a transgenic amyloid precursor protein mouse model of Alzheimer's disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Visuo-spatial learning and memory deficits on the Barnes maze in the 16-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Powerful beneficial effects of macrophage colony-stimulating factor on beta-amyloid deposition and cognitive impairment in Alzheimer's disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Selective ablation of bone marrow-derived dendritic cells increases amyloid plaques in a mouse Alzheimer's disease model.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Impaired spatial learning in the APPSwe + PSEN1DeltaE9 bigenic mouse model of Alzheimer's disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Developmental exposure to corticosterone: behavioral changes and differential effects on leukemia inhibitory factor (LIF) and corticotropin-releasing hormone (CRH) gene expression in the mouse

26 November 2018

1 reference

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Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Reducing cerebral microvascular amyloid-beta protein deposition diminishes regional neuroinflammation in vasculotropic mutant amyloid precursor protein transgenic mice.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

ACE I/D polymorphism is a risk factor of Alzheimer's disease but not of vascular dementia.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

The angiotensin 1-converting enzyme insertion (I)/deletion (D) polymorphism does not influence the extent of amyloid or tau pathology in patients with sporadic Alzheimer's disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Co-expression of multiple transgenes in mouse CNS: a comparison of strategies.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Microglial contribution to oxidative stress in Alzheimer's disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Role of the N-terminal Catalytic Domain of Angiotensin-converting Enzyme Investigated by Targeted Inactivation in Mice

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934162

Mice Lacking Endothelial Angiotensin-Converting Enzyme Have a Normal Blood Pressure

26 November 2018

1 reference

12 December 2020

Angiotensin-converting enzyme converts amyloid beta-protein 1-42 (Abeta(1-42)) to Abeta(1-40), and its inhibition enhances brain Abeta deposition

1 reference

12 December 2020

Common variants of ACE contribute to variable age-at-onset of Alzheimer’s disease

1 reference

12 December 2020

Angiotensin-converting enzyme (ACE) levels and activity in Alzheimer's disease, and relationship of perivascular ACE-1 to cerebral amyloid angiopathy

1 reference

12 December 2020

Inhibition of converting enzyme in brain tissue and cerebrospinal fluid of rats following chronic oral treatment with the converting enzyme inhibitors ramipril and Hoe 288

1 reference

12 December 2020

Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI66541

1 reference

21 August 2017

1 reference

21 August 2017

1 reference