Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions (Q30557795)

19 August 2017

Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions (English)

1 reference

19 August 2017

4

1 reference

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4 June 2020

Robert C. Ford

8

1 reference

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4 June 2020

Julie Forman-Kay

9

1 reference

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4 June 2020

author name string

Zoltan Bozoky

1

1 reference

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4 June 2020

Mickael Krzeminski

2

1 reference

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4 June 2020

Ranjith Muhandiram

3

1 reference

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4 June 2020

Ateeq Al-Zahrani

5

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4 June 2020

Philip J Thomas

6

1 reference

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4 June 2020

Raymond A Frizzell

7

1 reference

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4 June 2020

language of work or name

English

0 references

publication date

4 November 2013

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 August 2017

1 reference

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4 June 2020

volume

110

1 reference

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4 June 2020

issue

47

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4 June 2020

page(s)

E4427-36

1 reference

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Allosteric coupling between the intracellular coupling helix 4 and regulatory sites of the first nucleotide-binding domain of CFTR

4 June 2020

cites work

1 reference

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Intrinsically disordered proteins: a 10-year recap

20 June 2018

1 reference

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Interactions via intrinsically disordered regions: what kind of motifs?

20 June 2018

1 reference

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Phosphorylation-dependent 14-3-3 protein interactions regulate CFTR biogenesis

20 June 2018

1 reference

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Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR): THREE-DIMENSIONAL STRUCTURE AND LOCALIZATION OF A CHANNEL GATE

20 June 2018

1 reference

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Fuzziness: linking regulation to protein dynamics

20 June 2018

1 reference

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Structure/function implications in a dynamic complex of the intrinsically disordered Sic1 with the Cdc4 subunit of an SCF ubiquitin ligase

20 June 2018

1 reference

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Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant

20 June 2018

1 reference

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Bioinformatic and experimental survey of 14-3-3-binding sites.

20 June 2018

1 reference

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The role of dynamic conformational ensembles in biomolecular recognition

20 June 2018

1 reference

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ANCHOR: web server for predicting protein binding regions in disordered proteins.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Molecular models of the open and closed states of the whole human CFTR protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Protein dynamics and conformational disorder in molecular recognition

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Prediction of protein binding regions in disordered proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Three-dimensional reconstruction of human cystic fibrosis transmembrane conductance regulator chloride channel revealed an ellipsoidal structure with orifices beneath the putative transmembrane domain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Regulation of cell division by intrinsically unstructured proteins: intrinsic flexibility, modularity, and signaling conduits

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Local structural disorder imparts plasticity on linear motifs.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Intrinsic disorder is a common feature of hub proteins from four eukaryotic interactomes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Flexible nets. The roles of intrinsic disorder in protein interaction networks.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Disordered p27Kip1 exhibits intrinsic structure resembling the Cdk2/cyclin A-bound conformation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Phosphorylation of CFTR by PKA promotes binding of the regulatory domain

20 June 2018

1 reference

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RECOORD: a recalculated coordinate database of 500+ proteins from the PDB using restraints from the BioMagResBank

20 June 2018

1 reference

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Gating of CFTR by the STAS domain of SLC26 transporters

20 June 2018

1 reference

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Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life

20 June 2018

1 reference

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The importance of intrinsic disorder for protein phosphorylation

20 June 2018

1 reference

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HADDOCK: a protein-protein docking approach based on biochemical or biophysical information

20 June 2018

1 reference

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Effects of C-terminal deletions on cystic fibrosis transmembrane conductance regulator function in cystic fibrosis airway epithelia

20 June 2018

1 reference

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Roles of phosphorylation and helix propensity in the binding of the KIX domain of CREB-binding protein by constitutive (c-Myb) and inducible (CREB) activators

20 June 2018

1 reference

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Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation

20 June 2018

1 reference

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Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by its R domain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Severed channels probe regulation of gating of cystic fibrosis transmembrane conductance regulator by its cytoplasmic domains

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

A functional R domain from cystic fibrosis transmembrane conductance regulator is predominantly unstructured in solution

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Attenuated T2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Backbone 1H and 15N resonance assignments of the N-terminal SH3 domain of drk in folded and unfolded states using enhanced-sensitivity pulsed field gradient NMR techniques

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Domain location within the cystic fibrosis transmembrane conductance regulator protein investigated by electron microscopy and gold labelling.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Regulation of CFTR trafficking by its R domain

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Disorder and sequence repeats in hub proteins and their implications for network evolution.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839774

Stimulation of CFTR activity by its phosphorylated R domain.

26 November 2018

1 reference

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Conformational diversity and protein evolution--a 60-year-old hypothesis revisited

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24191035

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1315104110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24191035%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

0 references

1 reference

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4 June 2020

1 reference