NAP (davunetide) rescues neuronal dysfunction in a Drosophila model of tauopathy (Q30540857)

19 October 2017

NAP (davunetide) rescues neuronal dysfunction in a Drosophila model of tauopathy (English)

1 reference

19 October 2017

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1 reference

S Quraishe

1

1 reference

19 October 2017

C M Cowan

series ordinal

2

1 reference

19 October 2017

A Mudher

series ordinal

3

1 reference

19 October 2017

language of work or name

English

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publication date

16 April 2013

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19 October 2017

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19 October 2017

18

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19 October 2017

7

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19 October 2017

834-842

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The ADNP derived peptide, NAP modulates the tubulin pool: implication for neurotrophic and neuroprotective activities

19 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

The microtubule-stabilizing agent, epothilone D, reduces axonal dysfunction, neurotoxicity, cognitive deficits, and Alzheimer-like pathology in an interventional study with aged tau transgenic mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Critical appraisal of the role of davunetide in the treatment of progressive supranuclear palsy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Davunetide (NAP) as a preventative treatment for central nervous system complications in a diabetes rat model

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Modulation of protein-protein interactions as a therapeutic strategy for the treatment of neurodegenerative tauopathies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

The characterization of microtubule-stabilizing drugs as possible therapeutic agents for Alzheimer's disease and related tauopathies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Strategies for diminishing katanin-based loss of microtubules in tauopathic neurodegenerative diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Tau pathology and future therapeutics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Alzheimer's disease: clinical trials and drug development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Novel therapeutics for Alzheimer's disease: an update

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Peptide neuroprotection through specific interaction with brain tubulin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

NAP: research and development of a peptide derived from activity-dependent neuroprotective protein (ADNP).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Activity-dependent neurotrophic factor-9 and NAP promote neurite outgrowth in rat hippocampal and cortical cultures

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

NAP mechanisms of neuroprotection

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Microtubule Reduction in Alzheimer's Disease and Aging Is Independent of τ Filament Formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Tau neurofibrillary pathology and microtubule stability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Complete sequence of a novel protein containing a femtomolar-activity-dependent neuroprotective peptide

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

The phosphorylation of tau: a critical stage in neurodevelopment and neurodegenerative processes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

The pathogenesis of Alzheimer disease: an alternative to the amyloid hypothesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Soluble hyper-phosphorylated tau causes microtubule breakdown and functionally compromises normal tau in vivo.

20 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

Over-expression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

Microtubule-stabilising drugs for therapy of Alzheimer's disease and other neurodegenerative disorders with axonal transport impairments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

NAP, a femtomolar-acting peptide, protects the brain against ischemic injury by reducing apoptotic death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

NAP protects memory, increases soluble tau and reduces tau hyperphosphorylation in a tauopathy model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

Increased throughput assays of locomotor dysfunction in Drosophila larvae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

Amyloid peptide toxicity and microtubule-stabilizing drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

NAP, a neuroprotective drug candidate in clinical trials, stimulates microtubule assembly in the living cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

Hyperdynamic microtubules, cognitive deficits, and pathology are improved in tau transgenic mice with low doses of the microtubule-stabilizing agent BMS-241027.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

The peptide NAP promotes neuronal growth and differentiation through extracellular signal-regulated protein kinase and Akt pathways, and protects neurons co-cultured with astrocytes damaged by ethanol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

A femtomolar acting octapeptide interacts with tubulin and protects astrocytes against zinc intoxication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

NAP enhances neurodevelopment of newborn apolipoprotein E-deficient mice subjected to hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

Activity-dependent neuroprotective protein snippet NAP reduces tau hyperphosphorylation and enhances learning in a novel transgenic mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

The neuropeptide NAP provides neuroprotection against retinal ganglion cell damage after retinal ischemia and optic nerve crush

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

A Neuronal Microtubule-Interacting Agent, NAPVSIPQ, Reduces Tau Pathology and Enhances Cognitive Function in a Mouse Model of Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2013.32

A peptide derived from activity-dependent neuroprotective protein (ADNP) ameliorates injury response in closed head injury in mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690421

Intranasal NAP administration reduces accumulation of amyloid peptide and tau hyperphosphorylation in a transgenic mouse model of Alzheimer's disease at early pathological stage

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23587881

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MP.2013.32

1 reference

19 October 2017

1 reference

19 October 2017

1 reference