A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis (Q30535900)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23243209%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis (English)

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2

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20 February 2020

12

Craig Morrell

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20 February 2020

18

Jun-Ichi Abe

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20 February 2020

author name string

Nhat-Tu Le

1

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20 February 2020

Yuichiro Takei

3

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20 February 2020

Hakjoo Lee

4

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Chang-Hoon Woo

5

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Eugene Chang

6

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20 February 2020

Carolyn McClain

7

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Cheryl Hurley

8

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Xin Wang

9

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20 February 2020

Faqian Li

10

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20 February 2020

Haodong Xu

11

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20 February 2020

Mark A Sullivan

13

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Michael S Cohen

14

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Iana M Serafimova

15

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Jack Taunton

16

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20 February 2020

Keigi Fujiwara

17

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20 February 2020

language of work or name

English

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publication date

14 December 2012

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20 February 2020

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20 February 2020

volume

127

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20 February 2020

page(s)

486-499

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20 February 2020

issue

4

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p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction.

20 February 2020

cites work

1 reference

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Activation of protein kinase C isoforms and its impact on diabetic complications

28 July 2018

1 reference

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Hyperglycemia-induced reactive oxygen species increase expression of the receptor for advanced glycation end products (RAGE) and RAGE ligands

28 July 2018

1 reference

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Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology

28 July 2018

1 reference

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Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms.

28 July 2018

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Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2

28 July 2018

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Role of p90 ribosomal S6 kinase (p90RSK) in reactive oxygen species and protein kinase C beta (PKC-beta)-mediated cardiac troponin I phosphorylation

28 July 2018

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Hyperglycaemia-induced superoxide production decreases eNOS expression via AP-1 activation in aortic endothelial cells

28 July 2018

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Glycation, inflammation, and RAGE: a scaffold for the macrovascular complications of diabetes and beyond

28 July 2018

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ERK5 MAPK regulates embryonic angiogenesis and acts as a hypoxia-sensitive repressor of vascular endothelial growth factor expression

28 July 2018

1 reference

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Mechanisms underlying endothelial dysfunction in diabetes mellitus

28 July 2018

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Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

28 July 2018

1 reference

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ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain

28 July 2018

1 reference

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28 July 2018

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Endothelial dysfunction, hemodynamic forces, and atherogenesis

28 July 2018

1 reference

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Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice

28 July 2018

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Leukocyte-endothelial interaction is augmented by high glucose concentrations and hyperglycemia in a NF-kB-dependent fashion

28 July 2018

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Endothelial function in the isolated perfused mesentery and aortae of rats with streptozotocin-induced diabetes: effect of treatment with the aldose reductase inhibitor, ponalrestat

28 July 2018

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Extracellular signal-regulated kinase 5 SUMOylation antagonizes shear stress-induced antiinflammatory response and endothelial nitric oxide synthase expression in endothelial cells.

28 July 2018

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The MAP kinase ERK5 binds to and phosphorylates p90 RSK.

26 November 2018

1 reference

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Targeted deletion of BMK1/ERK5 in adult mice perturbs vascular integrity and leads to endothelial failure.

26 November 2018

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Mechanisms of amelioration of glucose-induced endothelial dysfunction following inhibition of protein kinase C in vivo

26 November 2018

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Chronic physiological shear stress inhibits tumor necrosis factor-induced proinflammatory responses in rabbit aorta perfused ex vivo

26 November 2018

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12 December 2020

The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma1 (PPARgamma1) mediates interaction with extracellular signal-regulated kinase 5 and PPARgamma1 transcriptional activation: involvement in flow-induced PPARgamma activation

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12 December 2020

A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice

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12 December 2020

Evidence for direct regulation of myocardial Na+/H+ exchanger isoform 1 phosphorylation and activity by 90-kDa ribosomal S6 kinase (RSK): effects of the novel and specific RSK inhibitor fmk on responses to alpha1-adrenergic stimulation

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12 December 2020

Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras

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12 December 2020

10.1161/CIRCULATIONAHA.112.116988

Identifiers

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20 February 2020

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20 February 2020

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