Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis. (Q30528812)

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10 March 2020

title

Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis (English)

1 reference

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10 March 2020

2

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10 March 2020

Ana C. Carrera

series ordinal

3

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10 March 2020

author name string

Virginia Silió

series ordinal

1

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10 March 2020

publication date

10 October 2012

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Molecular Biology of the Cell

10 March 2020

published in

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10 March 2020

volume

23

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10 March 2020

issue

23

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10 March 2020

page(s)

4526-4542

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describes a project that uses

10 March 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3510015/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Phosphorylation at serine 331 is required for Aurora B activation.

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Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC-spindle interaction to ensure proper microtubule dynamics

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Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction

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Constitutive Mad1 targeting to kinetochores uncouples checkpoint signalling from chromosome biorientation

20 June 2018

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Phosphoinositide 3-kinases p110alpha and p110beta regulate cell cycle entry, exhibiting distinct activation kinetics in G1 phase

20 June 2018

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Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin

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Chromosomal passengers: conducting cell division

20 June 2018

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Detection and correction of merotelic kinetochore orientation by Aurora B and its partners

20 June 2018

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Kinetochore dynein is required for chromosome motion and congression independent of the spindle checkpoint

20 June 2018

1 reference

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The spindle-assembly checkpoint in space and time

20 June 2018

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Cyclin B1/Cdk1 binds and phosphorylates Filamin A and regulates its ability to cross-link actin

20 June 2018

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Phylogenetic and structural analysis of centromeric DNA and kinetochore proteins

20 June 2018

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Phosphoinositide 3-kinase controls early and late events in mammalian cell division

20 June 2018

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Rod-Zw10-Zwilch: a key player in the spindle checkpoint

20 June 2018

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Spindle multipolarity is prevented by centrosomal clustering.

20 June 2018

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Timing and checkpoints in the regulation of mitotic progression

20 June 2018

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Correcting improper chromosome-spindle attachments during cell division

20 June 2018

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Distinct pools of proliferating cell nuclear antigen associated to DNA replication sites interact with the p125 subunit of DNA polymerase delta or DNA ligase I.

20 June 2018

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The mitotic checkpoint: a signaling pathway that allows a single unattached kinetochore to inhibit mitotic exit

20 June 2018

1 reference

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The mammalian passenger protein TD-60 is an RCC1 family member with an essential role in prometaphase to metaphase progression

20 June 2018

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Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension

20 June 2018

1 reference

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Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

20 June 2018

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The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

20 June 2018

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The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity

20 June 2018

1 reference

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Regulation of APC-Cdc20 by the spindle checkpoint

20 June 2018

1 reference

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Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

The kinase activity of aurora B is required for kinetochore-microtubule interactions during mitosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Probing the dynamics and functions of aurora B kinase in living cells during mitosis and cytokinesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Phosphoinositide 3-kinase in immunological systems

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Forkhead transcription factors contribute to execution of the mitotic programme in mammals

20 June 2018

1 reference

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Interaction between the Btk PH domain and phosphatidylinositol-3,4,5-trisphosphate directly regulates Btk.

20 June 2018

1 reference

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Growth-factor-dependent mitogenesis requires two distinct phases of signalling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Dynein is a transient kinetochore component whose binding is regulated by microtubule attachment, not tension

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Mammalian spindle orientation and position respond to changes in cell shape in a dynein-dependent fashion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

INCENP centromere and spindle targeting: identification of essential conserved motifs and involvement of heterochromatin protein HP1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Regulation of the VLA integrin-ligand interactions through the beta 1 subunit

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

PtdIns(3,4,5)P3 regulates spindle orientation in adherent cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Chk1 is required for spindle checkpoint function.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Induction of apoptosis by monastrol, an inhibitor of the mitotic kinesin Eg5, is independent of the spindle checkpoint

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

HURP Is a Ran-Importin β-Regulated Protein that Stabilizes Kinetochore Microtubules in the Vicinity of Chromosomes

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Survivin dynamics increases at centromeres during G2/M phase transition and is regulated by microtubule-attachment and Aurora B kinase activity

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Requirement for phosphatidylinositol-3 kinase activity during progression through S-phase and entry into mitosis.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Dynein and dynactin are localized to astral microtubules and at cortical sites in mitotic epithelial cells.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510015

Identification of centromere proteins in different mammalian cells

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23051731

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Incenp and an Aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23051731

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.E12-05-0371

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23051731%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23051731%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23051731%20AND%20SRC:MED&resulttype=core&format=json