Modification of anxiety-like behaviors by nociceptin/orphanin FQ (N/OFQ) and time-dependent changes in N/OFQ-NOP gene expression following ethanol withdrawal (Q30525737)

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English	Modification of anxiety-like behaviors by nociceptin/orphanin FQ (N/OFQ) and time-dependent changes in N/OFQ-NOP gene expression following ethanol withdrawal	scientific article

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

Modification of anxiety-like behaviors by nociceptin/orphanin FQ (N/OFQ) and time-dependent changes in N/OFQ-NOP gene expression following ethanol withdrawal (English)

1 reference

Europe PubMed Central

13 August 2017

0 references

1 reference

based on heuristic

inferred from title

Roberto Ciccocioppo

4

object named as

Roberto Ciccocioppo

1 reference

Europe PubMed Central

13 August 2017

author name string

Harinder Aujla

1

1 reference

Europe PubMed Central

13 August 2017

Rosalia Cannarsa

2

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Europe PubMed Central

13 August 2017

Patrizia Romualdi

3

1 reference

Europe PubMed Central

13 August 2017

Rémi Martin-Fardon

5

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Europe PubMed Central

13 August 2017

Friedbert Weiss

6

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Europe PubMed Central

13 August 2017

publication date

15 July 2012

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Europe PubMed Central

13 August 2017

Addiction Biology

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Europe PubMed Central

13 August 2017

18

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Europe PubMed Central

13 August 2017

467-479

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Europe PubMed Central

13 August 2017

3

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Europe PubMed Central

13 August 2017

Activation of brain NOP receptors attenuates acute and protracted alcohol withdrawal symptoms in the rat.

1 reference

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Direct inhibition of hypocretin/orexin neurons in the lateral hypothalamus by nociceptin/orphanin FQ blocks stress-induced analgesia in rats

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20 June 2018

Effects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependence

1 reference

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Revisiting intragastric ethanol intubation as a dependence induction method for studies of ethanol reward and motivation in rats

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Role of innate and drug-induced dysregulation of brain stress and arousal systems in addiction: Focus on corticotropin-releasing factor, nociceptin/orphanin FQ, and orexin/hypocretin

1 reference

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Nociceptin/orphanin FQ and NOP receptor gene regulation after acute or repeated social defeat stress

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Neurotransmitter systems in alcohol dependence

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Neurobiological substrates for the dark side of compulsivity in addiction

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A role for brain stress systems in addiction

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Dysregulation of nociceptin/orphanin FQ activity in the amygdala is linked to excessive alcohol drinking in the rat.

1 reference

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20 June 2018

Association between the nociceptin receptor gene (OPRL1) single nucleotide polymorphisms and alcohol dependence

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Synaptic plasticity and addiction

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20 June 2018

Stress, dysregulation of drug reward pathways, and the transition to drug dependence

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20 June 2018

Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stress

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477306

20 June 2018

Nociceptin/orphanin FQ presynaptically decreases GABAergic transmission and blocks the ethanol-induced increase of GABA release in central amygdala

1 reference

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20 June 2018

The orexin system regulates alcohol-seeking in rats

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20 June 2018

Anxiogenic and aversive effects of corticotropin-releasing factor (CRF) in the bed nucleus of the stria terminalis in the rat: role of CRF receptor subtypes.

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20 June 2018

Nociceptin/orphanin FQ acts as a functional antagonist of corticotropin-releasing factor to inhibit its anorectic effect

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477306

20 June 2018

Attenuation of ethanol self-administration and of conditioned reinstatement of alcohol-seeking behaviour by the antiopioid peptide nociceptin/orphanin FQ in alcohol-preferring rats

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20 June 2018

The bed nucleus is a neuroanatomical substrate for the anorectic effect of corticotropin-releasing factor and for its reversal by nociceptin/orphanin FQ.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477306

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Reversal of stress- and CRF-induced anorexia in rats by the synthetic nociceptin/orphanin FQ receptor agonist, Ro 64-6198.

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20 June 2018

Pharmacological profile of nociceptin/orphanin FQ receptors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477306

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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20 June 2018

Nocistatin: a novel neuropeptide encoded by the gene for the nociceptin/orphanin FQ precursor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477306

20 June 2018

The orphanin FQ/nociceptin gene: structure, tissue distribution of expression and functional implications obtained from knockout mice

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20 June 2018

Nociceptin prevents stress-induced ethanol- but not cocaine-seeking behavior in rats.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477306

20 June 2018

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477306

20 June 2018

Orphanin FQ acts as an anxiolytic to attenuate behavioral responses to stress

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477306

20 June 2018

Nociceptin stimulates locomotion and exploratory behaviour in mice.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477306

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Rats rapidly develop tolerance to the locomotor-inhibiting effects of the novel neuropeptide orphanin FQ.

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Corticosteroids and the control of function in the hypothalamo-pituitary-adrenal (HPA) axis.

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Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin

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Rats with extended access to cocaine exhibit increased stress reactivity and sensitivity to the anxiolytic-like effects of the mGluR 2/3 agonist LY379268 during abstinence

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21 January 2018

Effect of nociceptin on alcohol intake in alcohol-preferring rats.

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21 January 2018

Stimuli linked to ethanol availability activate hypothalamic CART and orexin neurons in a reinstatement model of relapse.

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Nociceptin/orphanin FQ increases anxiety-related behavior and circulating levels of corticosterone during neophobic tests of anxiety.

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https://api.crossref.org/works/10.1111%2FJ.1369-1600.2012.00466.X

21 January 2018

Effects of nociceptin on the exploratory behavior of mice in the hole-board test

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Nocistatin and its derivatives antagonize the impairment of short-term acquisition induced by nociceptin.

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21 January 2018

Excitotoxic lesions of the septum produce anxiolytic effects in the elevated plus-maze and the shock-probe burying tests

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Microinjection of a corticotropin-releasing factor antagonist into the central nucleus of the amygdala reverses anxiogenic-like effects of ethanol withdrawal.

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21 January 2018

Functional antagonism between nociceptin/orphanin FQ (N/OFQ) and corticotropin-releasing factor (CRF) in the rat brain: evidence for involvement of the bed nucleus of the stria terminalis.

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Nociceptin/orphanin FQ modulates spatial learning via ORL-1 receptors in the dorsal hippocampus of the rat.

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21 January 2018

Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: regulation by corticotropin-releasing factor

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Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinence

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Association analysis of genes encoding the nociceptin receptor (OPRL1) and its endogenous ligand (PNOC) with alcohol or illicit drug dependence

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Subtype-selective corticotropin-releasing factor receptor agonists exert contrasting, but not opposite, effects on anxiety-related behavior in rats.

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Remission and resurgence of anxiety-like behavior across protracted withdrawal stages in ethanol-dependent rats.

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Changes in levels of regional CRF-like-immunoreactivity and plasma corticosterone during protracted drug withdrawal in dependent rats

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Different alcohol exposures induce selective alterations on the expression of dynorphin and nociceptin systems related genes in rat brain

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Localization of orphanin FQ (nociceptin) peptide and messenger RNA in the central nervous system of the rat.

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Time-dependent quantifiable withdrawal from ethanol in the rat: effect of method of dependence induction

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Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response

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https://pubmed.ncbi.nlm.nih.gov/22804785

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10.1111/J.1369-1600.2012.00466.X

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Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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