Proteasome inhibition drives HDAC6-dependent recruitment of tau to aggresomes (Q30502900)

15 October 2017

Proteasome inhibition drives HDAC6-dependent recruitment of tau to aggresomes (English)

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15 October 2017

Chris R Guthrie

1

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15 October 2017

Brian C Kraemer

series ordinal

2

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15 October 2017

language of work or name

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22 February 2011

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Journal of Molecular Neuroscience

15 October 2017

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15 October 2017

45

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15 October 2017

32-41

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15 October 2017

1

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https://scigraph.springernature.com/pub.10.1007/s12031-011-9502-x

15 October 2017

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Concentration-dependent effects of proteasomal inhibition on tau processing in a cellular model of tauopathy.

20 June 2018

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20 June 2018

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Histone deacetylase 6 interacts with the microtubule-associated protein tau

20 June 2018

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Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease

20 June 2018

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The ubiquitin-proteasome system in Alzheimer's disease

20 June 2018

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Aggresome formation and neurodegenerative diseases: therapeutic implications

20 June 2018

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Autophagy, amyloidogenesis and Alzheimer disease

20 June 2018

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Tau aggregation and toxicity in a cell culture model of tauopathy

20 June 2018

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Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

20 June 2018

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Tau phosphorylation and proteolysis: insights and perspectives.

20 June 2018

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Inducible expression of Tau repeat domain in cell models of tauopathy: aggregation is toxic to cells but can be reversed by inhibitor drugs

20 June 2018

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HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

20 June 2018

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Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation

20 June 2018

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Phosphorylated tau and the neurodegenerative foldopathies

20 June 2018

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The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

20 June 2018

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CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell Survival

20 June 2018

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Proteasome Inhibition Stabilizes Tau Inclusions in Oligodendroglial Cells that Occur after Treatment with Okadaic Acid

20 June 2018

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Intracellular clusterin causes juxtanuclear aggregate formation and mitochondrial alteration

20 June 2018

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The role of tau in Alzheimer's disease

20 June 2018

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Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells

20 June 2018

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Tau phosphorylation at serine 396 and serine 404 by human recombinant tau protein kinase II inhibits tau's ability to promote microtubule assembly

20 June 2018

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Aggresomes: a cellular response to misfolded proteins

20 June 2018

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The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology.

20 June 2018

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A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B

20 June 2018

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Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

20 June 2018

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Proteasomal degradation of tau protein

21 January 2018

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Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules

21 January 2018

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Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17.

21 January 2018

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Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform

21 January 2018

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Tau--an inhibitor of deacetylase HDAC6 function.

21 January 2018

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Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau.

21 January 2018

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Huntingtin fragments form aggresome-like inclusion bodies in mammalian cells

21 January 2018

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Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease

26 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145040

Differential inhibition of calpain and proteasome activities by peptidyl aldehydes of di-leucine and tri-leucine

26 November 2018

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12 December 2020

Polymerization of tau peptides into fibrillar structures. The effect of FTDP-17 mutations

1 reference

12 December 2020

Effects of frontotemporal dementia FTDP-17 mutations on heparin-induced assembly of tau filaments

1 reference

12 December 2020

Lactacystin, a specific inhibitor of the proteasome, induces apoptosis in human monoblast U937 cells

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12 December 2020

Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias

1 reference

12 December 2020

10.1007/S12031-011-9502-X

Identifiers

DOI

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Dimensions Publication ID

15 October 2017

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15 October 2017

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