Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4 (Q30498016)

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19 January 2020

title

Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21220308%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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7

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19 January 2020

Mirko Baruscotti

1

1 reference

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19 January 2020

Annalisa Bucchi

2

1 reference

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19 January 2020

Gian Giacomo Consalez

5

1 reference

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19 January 2020

Karina Casali

8

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19 January 2020

Andrea Barbuti

10

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19 January 2020

Dario DiFrancesco

11

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19 January 2020

3

Carlo Viscomi

1 reference

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19 January 2020

author name string

Giacomo Mandelli

4

1 reference

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19 January 2020

Tomaso Gnecchi-Rusconi

6

1 reference

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19 January 2020

Stefano Micheloni

9

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19 January 2020

language of work or name

English

0 references

publication date

10 January 2011

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

19 January 2020

published in

1 reference

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19 January 2020

volume

108

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19 January 2020

page(s)

1705-1710

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19 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21220308%20AND%20SRC:MED&resulttype=core&format=json

Funny channel-based pacemaking

19 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

Hyperpolarization-activated cation channels: from genes to function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

Control of heart rate by cAMP sensitivity of HCN channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

What keeps us ticking: a funny current, a calcium clock, or both?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

Formation of the sinus node head and differentiation of sinus node myocardium are independently regulated by Tbx18 and Tbx3

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

Genesis and regulation of the heart automaticity.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

Tamoxifen-inducible gene deletion in the cardiac conduction system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

Role of pacemaking current in cardiac nodes: insights from a comparative study of sinoatrial node and atrioventricular node

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

Molecular pathway for the localized formation of the sinoatrial node

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

Heart rate lowering by specific and selective I(f) current inhibition with ivabradine: a new therapeutic perspective in cardiovascular disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

Heteromeric HCN1-HCN4 channels: a comparison with native pacemaker channels from the rabbit sinoatrial node

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

Hyperpolarization-activated cation currents: from molecules to physiological function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

Distribution of the pacemaker HCN4 channel mRNA and protein in the rabbit sinoatrial node.

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1010122108

Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1010122108

Slow current systems in the A-V node of the rabbit heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1010122108

Characteristics of single cells isolated from the atrioventricular node of the adult guinea-pig heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1010122108

Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1010122108

Cellular expression and functional characterization of four hyperpolarization-activated pacemaker channels in cardiac and neuronal tissues

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029742

Expression of Kir2.1 and Kir6.2 transgenes under the control of the α-MHC promoter in the sinoatrial and atrioventricular nodes in transgenic mice

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21220308

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential Expression of Ion Channel Transcripts in Atrial Muscle and Sinoatrial Node in Rabbit

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21220308

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Organisation of the mouse sinoatrial node: structure and expression of HCN channels

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21220308

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1010122108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21220308%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21220308%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference