The absence of the pro-antioxidant transcription factor Nrf2 exacerbates experimental autoimmune encephalomyelitis (Q30495467)

15 October 2017

The absence of the pro-antioxidant transcription factor Nrf2 exacerbates experimental autoimmune encephalomyelitis (English)

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experimental autoimmune encephalomyelitis

15 October 2017

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author name string

Delinda A Johnson

1

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15 October 2017

Sara Amirahmadi

2

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15 October 2017

Charlotte Ward

3

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15 October 2017

Zsuszanna Fabry

4

1 reference

15 October 2017

Jeffrey A Johnson

5

1 reference

15 October 2017

12 November 2009

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15 October 2017

Toxicological Sciences

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15 October 2017

114

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15 October 2017

237-246

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15 October 2017

2

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describes a project that uses

15 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2902921/fullTextXML

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inferred from PubMed Central ID database lookup

cites work

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Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

20 June 2018

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The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration

20 June 2018

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Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis

20 June 2018

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Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles.

20 June 2018

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The transcription factor Nrf2 is a therapeutic target against brain inflammation

20 June 2018

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Preclinical evaluation of targeting the Nrf2 pathway by triterpenoids (CDDO-Im and CDDO-Me) for protection from LPS-induced inflammatory response and reactive oxygen species in human peripheral blood mononuclear cells and neutrophils

20 June 2018

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Pathogenesis of myelin/oligodendrocyte damage in multiple sclerosis

20 June 2018

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Nrf2-mediated protection against 6-hydroxydopamine

20 June 2018

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Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide

20 June 2018

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NAD(P)H:quinone oxidoreductase 1 expression in multiple sclerosis lesions

20 June 2018

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Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

20 June 2018

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Biozzi mice: of mice and human neurological diseases

20 June 2018

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Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription

20 June 2018

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Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells

20 June 2018

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Genetic dissection of systemic autoimmune disease in Nrf2-deficient mice

20 June 2018

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Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes

20 June 2018

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Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2)

20 June 2018

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Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

20 June 2018

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Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress

20 June 2018

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Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis

20 June 2018

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Expression of inducible nitric oxide synthase and nitrotyrosine in multiple sclerosis lesions

20 June 2018

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An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

20 June 2018

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20 June 2018

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Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

20 June 2018

1 reference

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

20 June 2018

1 reference

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NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development

20 June 2018

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TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination.

20 June 2018

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Electrophilic chemicals but not UV irradiation or reactive oxygen species activate Nrf2 in keratinocytes in vitro and in vivo.

21 January 2018

1 reference

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Lipopolysaccharide and interferon-gamma-induced nitric oxide production and protein oxidation in mouse peritoneal macrophages are affected by glutathione peroxidase-1 gene knockout.

21 January 2018

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Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles

21 January 2018

1 reference

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Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult.

21 January 2018

1 reference

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Neuronal sensitivity to kainic acid is dependent on the Nrf2-mediated actions of the antioxidant response element.

21 January 2018

1 reference

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Nrf2, a multi-organ protector?

21 January 2018

1 reference

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Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP274

Severe oxidative damage in multiple sclerosis lesions coincides with enhanced antioxidant enzyme expression.

21 January 2018

1 reference

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Molecular changes in white matter adjacent to an active demyelinating lesion in early multiple sclerosis.

21 January 2018

1 reference

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Nrf2-deficient female mice develop lupus-like autoimmune nephritis

26 November 2018

1 reference

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26 November 2018

Identifiers

DOI

10.1093/TOXSCI/KFP274

1 reference

15 October 2017

1 reference

15 October 2017

1 reference