Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells (Q30493841)

14 September 2017

Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells (English)

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14 September 2017

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Li Lin

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14 September 2017

Brian Hutzen

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Mingxin Zuo

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Sarah Ball

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Stephanie Deangelis

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Elizabeth Foust

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14 September 2017

Bulbul Pandit

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Michael A Ihnat

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Satyendra S Shenoy

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14 September 2017

Samuel Kulp

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Pui-Kai Li

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14 September 2017

Chenglong Li

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14 September 2017

James Fuchs

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14 September 2017

Jiayuh Lin

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14 September 2017

language of work or name

English

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publication date

9 March 2010

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70

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6

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2445-2454

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describes a project that uses

14 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2843552/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation

20 June 2018

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Stattic: a small-molecule inhibitor of STAT3 activation and dimerization

20 June 2018

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A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo

20 June 2018

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Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane).

20 June 2018

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A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells

20 June 2018

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STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells.

20 June 2018

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The STATs of cancer--new molecular targets come of age

20 June 2018

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STAT-1: a novel regulator of apoptosis

20 June 2018

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Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

20 June 2018

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Curcumin (Diferuloylmethane) Inhibits Constitutive and IL-6-Inducible STAT3 Phosphorylation in Human Multiple Myeloma Cells

20 June 2018

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20 June 2018

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Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells

20 June 2018

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Transcription factors as targets for cancer therapy

20 June 2018

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20 June 2018

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Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention

20 June 2018

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Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells

20 June 2018

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Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation

20 June 2018

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Roles of STAT3 defined by tissue-specific gene targeting

20 June 2018

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20 June 2018

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Stat3 activation by Src induces specific gene regulation and is required for cell transformation

20 June 2018

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Mutational analysis of acute-phase response factor/Stat3 activation and dimerization

20 June 2018

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Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

20 June 2018

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Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma

20 June 2018

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20 June 2018

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Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction

20 June 2018

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Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

20 June 2018

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Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

20 June 2018

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Investigation of the binding determinants of phosphopeptides targeted to the SRC homology 2 domain of the signal transducer and activator of transcription 3. Development of a high-affinity peptide inhibitor

20 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843552

Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843552

Angiogenesis in lipoma: An experimental study in the chick embryo chorioallantoic membrane

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843552

10.1158/0008-5472.CAN-09-2468

26 November 2018

Identifiers

DOI

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14 September 2017

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14 September 2017

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