Gangliosides play pivotal roles in the regulation of complement systems and in the maintenance of integrity in nerve tissues (Q30492292)

20 August 2017

Gangliosides play pivotal roles in the regulation of complement systems and in the maintenance of integrity in nerve tissues (English)

1 reference

20 August 2017

Yuhsuke Ohmi

1

1 reference

20 August 2017

Orie Tajima

2

1 reference

20 August 2017

Yuki Ohkawa

3

1 reference

20 August 2017

Atsushi Mori

4

1 reference

20 August 2017

Yasuo Sugiura

5

1 reference

20 August 2017

Keiko Furukawa

6

1 reference

20 August 2017

Koichi Furukawa

7

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20 August 2017

language of work or name

English

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publication date

11 December 2009

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20 August 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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20 August 2017

106

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20 August 2017

52

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20 August 2017

22405-22410

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Biosynthesis, remodelling and functions of mammalian GPI-anchored proteins: recent progress

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Impaired hypoglossal nerve regeneration in mutant mice lacking complex gangliosides: down-regulation of neurotrophic factors and receptors as possible mechanisms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

The classical complement cascade mediates CNS synapse elimination

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Complement deficiencies and systemic lupus erythematosus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Lipid rafts in health and disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Complement: a novel factor in basal and ischemia-induced neurogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Cell-specific deletion of glucosylceramide synthase in brain leads to severe neural defects after birth.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Characterization of C3a and C5a receptors in rat cerebellar granule neurons during maturation. Neuroprotective effect of C5a against apoptotic cell death

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Overexpressed GM1 suppresses nerve growth factor (NGF) signals by modulating the intracellular localization of NGF receptors and membrane fluidity in PC12 cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Lipid rafts: elusive or illusive?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Activation of complement in the central nervous system: roles in neurodegeneration and neuroprotection

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Complement in central nervous system inflammation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Complement in Alzheimer's disease: opportunities for modulating protective and pathogenic events

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Roles of lipid rafts in membrane transport

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

A perspective on inflammation in Alzheimer's disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Detection of complement alternative pathway mRNA and proteins in the Alzheimer's disease brain.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Spontaneous classical pathway activation and deficiency of membrane regulators render human neurons susceptible to complement lysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Complement components of the innate immune system in health and disease in the CNS.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

A vital role for glycosphingolipid synthesis during development and differentiation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Up-regulated production and activation of the complement system in Alzheimer's disease brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Neurons express proteins of the classical complement pathway in Alzheimer disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Functional rafts in cell membranes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Complement activation by beta-amyloid in Alzheimer disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792163

Sensory nerve-dominant nerve degeneration and remodeling in the mutant mice lacking complex gangliosides.

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912336106

Reduced motor and sensory functions and emotional response in GM3-only mice: emergence from early stage of life and exacerbation with aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912336106

The importance of inflammatory mechanisms in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912336106

Complement activation by neurofibrillary tangles in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912336106

Complement C5a receptor-mediated signaling may be involved in neurodegeneration in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912336106

Rafts defined: a report on the Keystone Symposium on Lipid Rafts and Cell Function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912336106

Caveolin-1 is essential for liver regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912336106

Effect of ganglioside and tetraspanins in microdomains on interaction of integrins with fibroblast growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912336106

b-series Ganglioside deficiency exhibits no definite changes in the neurogenesis and the sensitivity to Fas-mediated apoptosis but impairs regeneration of the lesioned hypoglossal nerve

21 January 2018

1 reference

12 December 2020

Induction of decay-accelerating factor by cytokines or the membrane-attack complex protects vascular endothelial cells against complement deposition

1 reference

12 December 2020

Deficiency of complement defense protein CD59 may contribute to neurodegeneration in Alzheimer's disease

1 reference

12 December 2020

Refractory skin injury in complex knock-out mice expressing only the GM3 ganglioside

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0912336106

1 reference

20 August 2017

0 references

1 reference

20 August 2017

PubMed publication ID

20018737

1 reference