Nontarget DNA binding shapes the dynamic landscape for enzymatic recognition of DNA damage (Q30488332)

19 August 2017

Nontarget DNA binding shapes the dynamic landscape for enzymatic recognition of DNA damage (English)

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19 August 2017

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Joshua I Friedman

1

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19 August 2017

Ananya Majumdar

series ordinal

2

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19 August 2017

James T Stivers

series ordinal

3

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19 August 2017

language of work or name

English

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publication date

1 April 2009

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19 August 2017

Nucleic Acids Research

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19 August 2017

37

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19 August 2017

11

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19 August 2017

3493-3500

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Uracil DNA glycosylase uses DNA hopping and short-range sliding to trap extrahelical uracils

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

Characterization of enzyme motions by solution NMR relaxation dispersion.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

Extrahelical damaged base recognition by DNA glycosylase enzymes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

Enzymatic capture of an extrahelical thymine in the search for uracil in DNA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

Genomic uracil and human disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

Relating protein motion to catalysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

Intrinsic dynamics of an enzyme underlies catalysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

NMR chemical shift and relaxation measurements provide evidence for the coupled folding and binding of the p53 transactivation domain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

Dynamic opening of DNA during the enzymatic search for a damaged base

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

ElNemo: a normal mode web server for protein movement analysis and the generation of templates for molecular replacement

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

A mechanistic perspective on the chemistry of DNA repair glycosylases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

Nuclear magnetic resonance methods for quantifying microsecond-to-millisecond motions in biological macromolecules

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

Solution-state NMR investigations of triosephosphate isomerase active site loop motion: ligand release in relation to active site loop dynamics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

Kinetic mechanism of damage site recognition and uracil flipping by Escherichia coli uracil DNA glycosylase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

The catalytic power of uracil DNA glycosylase in the opening of thymine base pairs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

DNA recognition by the brinker repressor--an extreme case of coupling between binding and folding.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

The origins of high-affinity enzyme binding to an extrahelical DNA base

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

NMR R1 rho rotating-frame relaxation with weak radio frequency fields.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699497

[13C]-constant-time [15N,1H]-TROSY-HNCA for sequential assignments of large proteins

26 November 2018

1 reference

12 December 2020

A TROSY CPMG sequence for characterizing chemical exchange in large proteins

1 reference

12 December 2020

Two-state allosteric behavior in a single-domain signaling protein

1 reference

12 December 2020

Improved 3D triple resonance experiments, HNN and HN(C)N, for HN and 15N sequential correlations in (13C, 15N) labeled proteins: application to unfolded proteins

1 reference

12 December 2020

Evidence for flexibility in the function of ribonuclease A

1 reference

12 December 2020

NMR characterization of the dynamics of biomacromolecules

1 reference

12 December 2020

Flap opening and dimer-interface flexibility in the free and inhibitor-bound HIV protease, and their implications for function

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKP161

1 reference

19 August 2017

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19 August 2017

1 reference