FTDP-17 mutations in Tau alter the regulation of microtubule dynamics: an "alternative core" model for normal and pathological Tau action. (Q30485126)

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24 December 2019

title

FTDP-17 mutations in Tau alter the regulation of microtubule dynamics: an "alternative core" model for normal and pathological Tau action (English)

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24 December 2019

1

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24 December 2019

author name string

Sasha F Levy

2

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24 December 2019

Michelle Gaylord

3

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24 December 2019

Arnab Bhattacharya

4

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Ambuj K Singh

5

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24 December 2019

Mary Ann Jordan

6

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24 December 2019

Leslie Wilson

7

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24 December 2019

Stuart C Feinstein

8

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24 December 2019

language of work or name

English

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publication date

21 October 2008

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Journal of Biological Chemistry

24 December 2019

published in

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24 December 2019

volume

283

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issue

52

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24 December 2019

page(s)

36406-36415

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A general modeling and visualization tool for comparing different members of a group: application to studying tau-mediated regulation of microtubule dynamics.

24 December 2019

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Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics

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In vitro polymerization of tau protein monitored by laser light scattering: method and application to the study of FTDP-17 mutants

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau

20 June 2018

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20 June 2018

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Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17.

20 June 2018

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Three- and four-repeat tau regulate the dynamic instability of two distinct microtubule subpopulations in qualitatively different manners. Implications for neurodegeneration

21 January 2018

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Kinetic Stabilization of Microtubule Dynamics at Steady State by Tau and Microtubule-Binding Domains of Tau

21 January 2018

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Structural and functional differences between 3-repeat and 4-repeat tau isoforms. Implications for normal tau function and the onset of neurodegenetative disease

21 January 2018

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Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

21 January 2018

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Untangling memory deficits.

21 January 2018

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FTDP-17 mutations compromise the ability of tau to regulate microtubule dynamics in cells

21 January 2018

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Functional characterization of FTDP-17 tau gene mutations through their effects on Xenopus oocyte maturation.

21 January 2018

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Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

21 January 2018

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Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

21 January 2018

1 reference

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FTDP-17 mutations N279K and S305N in tau produce increased splicing of exon 10

21 January 2018

1 reference

12 December 2020

Polymerization of tau peptides into fibrillar structures. The effect of FTDP-17 mutations

1 reference

12 December 2020

Effects of frontotemporal dementia FTDP-17 mutations on heparin-induced assembly of tau filaments

1 reference

12 December 2020

Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias

1 reference

12 December 2020

Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure

1 reference

12 December 2020

Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M803519200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18940799%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18940799%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

PubMed publication ID

18940799

1 reference