A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation (Q30480370)

12 August 2017

A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation (English)

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positive regulation of microtubule polymerization

12 August 2017

1 reference

GOA release 2020-03-11

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GOA release 2020-03-11

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Lee A Ligon

6

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Erika Holzbaur

12

object named as

Erika L F Holzbaur

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12 August 2017

Jennifer R Levy

1

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12 August 2017

Charlotte J Sumner

2

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12 August 2017

Juliane P Caviston

3

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12 August 2017

Mariko K Tokito

4

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12 August 2017

Srikanth Ranganathan

5

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12 August 2017

Karen E Wallace

7

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12 August 2017

Bernadette H LaMonte

8

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12 August 2017

George G Harmison

9

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12 August 2017

Imke Puls

10

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12 August 2017

Kenneth H Fischbeck

11

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12 August 2017

language of work or name

English

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publication date

1 February 2006

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12 August 2017

13

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inferred from page(s)

published in

Journal of Cell Biology

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12 August 2017

172

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12 August 2017

5

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12 August 2017

733-745

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describes a project that uses

12 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2063705/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Glycine residues appear to be evolutionarily conserved for their ability to inhibit aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Distal spinal and bulbar muscular atrophy caused by dynactin mutation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Unraveling the mechanisms involved in motor neuron degeneration in ALS

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Motor neurons rely on motor proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Roles of molecular chaperones in protein misfolding diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

A role for cytoplasmic dynein and LIS1 in directed cell movement

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

The microtubule plus-end proteins EB1 and dynactin have differential effects on microtubule polymerization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Function of dynein and dynactin in herpes simplex virus capsid transport

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

The balance of power in RNA trafficking

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

The hydroxyl of threonine 13 of the bovine 70-kDa heat shock cognate protein is essential for transducing the ATP-induced conformational change

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Functionally distinct isoforms of dynactin are expressed in human neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Cytoplasmic dynein function is essential in Drosophila melanogaster

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1)

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Analysis of visual system development in Drosophila melanogaster: mutations at the Glued locus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Embryonic mouse spinal cord motor neuron hybrid cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Cytoplasmic dynein participates in the centrosomal localization of the Golgi complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063705

Mutations in dynein link motor neuron degeneration to defects in retrograde transport

20 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200511068

Structural basis for the activation of microtubule assembly by the EB1 and p150Glued complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200511068

Cytoplasmic dynein/dynactin mediates the assembly of aggresomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200511068

Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200511068

Dynein binds to beta-catenin and may tether microtubules at adherens junctions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200511068

Expression of the p150Glued component of the dynactin complex in developing and adult rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200511068

Mutant dynactin in motor neuron disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200511068

A cell culture model for androgen effects in motor neurons

21 January 2018

1 reference

12 December 2020

Colocalization of cytoplasmic dynein with dynactin and CLIP-170 at microtubule distal ends

1 reference

12 December 2020

Extracellular heat shock protein 70: a critical component for motoneuron survival

1 reference

12 December 2020

Functional analysis of CLIP-115 and its binding to microtubules

1 reference

12 December 2020

Subcellular localization of SV2 and other secretory vesicle components in PC12 cells by an efficient method of preembedding EM immunocytochemistry for cell cultures

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200511068

1 reference

release_rmhpejf33re2vokmjg2dlayb44

12 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rmhpejf33re2vokmjg2dlayb44

24 November 2022

mapped directly with Wikidata item

1 reference

12 August 2017

1 reference