Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content (Q30479724)

10 August 2017

Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content (English)

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10 August 2017

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Marya F McCarty

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10 August 2017

Ray J Somcio

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10 August 2017

Oliver Stoeltzing

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10 August 2017

Jane Wey

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10 August 2017

Fan Fan

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10 August 2017

Wenbiao Liu

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10 August 2017

Corazon Bucana

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10 August 2017

Lee M Ellis

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10 August 2017

language of work or name

English

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publication date

1 August 2007

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Journal of Clinical Investigation

10 August 2017

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10 August 2017

117

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10 August 2017

8

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10 August 2017

2114-2122

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describes a project that uses

10 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1913488/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Pericytes and vascular stability

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Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model.

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Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors

20 June 2018

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Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

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Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment

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Diversity within pericytes

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Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal

20 June 2018

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Expression in lung carcinomas of platelet-derived growth factor and its receptors.

20 June 2018

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Pericyte loss and microaneurysm formation in PDGF-B-deficient mice

20 June 2018

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Platelet-derived growth factor in human glioma

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Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

20 June 2018

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Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.

20 June 2018

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Transforming potential of human c-sis nucleotide sequences encoding platelet-derived growth factor.

20 June 2018

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Transformation of NIH 3T3 cells by a human c-sis cDNA clone

20 June 2018

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Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells

20 June 2018

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Human melanoma cell lines of primary and metastatic origin express the genes encoding the chains of platelet-derived growth factor (PDGF) and produce a PDGF-like growth factor

20 June 2018

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An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes

20 June 2018

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Effects of hyperoxia on microvascular cells in vitro

20 June 2018

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Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival

20 June 2018

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Tyrosine kinase inhibition of multiple angiogenic growth factor receptors improves survival in mice bearing colon cancer liver metastases by inhibition of endothelial cell survival mechanisms

26 November 2018

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Heterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapies.

26 November 2018

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Platelet-derived growth factor-B/v-sis confers a tumorigenic and metastatic phenotype to human T98G glioblastoma cells

26 November 2018

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Induction of VEGF in perivascular cells defines a potential paracrine mechanism for endothelial cell survival

26 November 2018

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12 December 2020

TGF beta is required for the formation of capillary-like structures in three-dimensional cocultures of 10T1/2 and endothelial cells

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12 December 2020

Tumor-derived platelet-derived growth factor-BB plays a critical role in osteosclerotic bone metastasis in an animal model of human breast cancer

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12 December 2020

Growth factor production by human colon carcinoma cell lines

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12 December 2020

Expression of several growth factors and their receptor genes in human colon carcinomas

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12 December 2020

Stromal expression of platelet-derived growth factor beta-receptor and platelet-derived growth factor B-chain in colorectal cancer

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12 December 2020

Expression of platelet-derived growth factor and its receptors by two pre-B acute lymphocytic leukemia cell lines

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12 December 2020

Detection of c- sis Transcripts and Synthesis of PDGF-Like Proteins by Human Osteosarcoma Cells

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12 December 2020

Coexpression of a PDGF-like growth factor and PDGF receptors in a human osteosarcoma cell line: Implications for autocrine receptor activation

1 reference

12 December 2020

Induction of platelet-derived growth factor A and B chains and over-expression of their receptors in human pancreatic cancer

1 reference

12 December 2020

Platelet-derived growth factor (PDGF) BB acts as a chemoattractant for human malignant mesothelioma cells via PDGF receptor beta-integrin alpha3beta1 interaction

1 reference

12 December 2020

Endothelial Cells Modulate the Proliferation of Mural Cell Precursors via Platelet-Derived Growth Factor-BB and Heterotypic Cell Contact

1 reference

12 December 2020

Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumors

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI31334

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10 August 2017

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10 August 2017

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