A 200-kb region of human chromosome 22q11.2 confers antipsychotic-responsive behavioral abnormalities in mice (Q30476572)

24 September 2017

A 200-kb region of human chromosome 22q11.2 confers antipsychotic-responsive behavioral abnormalities in mice (English)

1 reference

24 September 2017

Bernice Morrow

8

0 references

author name string

Noboru Hiroi

1

1 reference

24 September 2017

Hongwen Zhu

2

1 reference

24 September 2017

Moonsook Lee

3

1 reference

24 September 2017

Birgit Funke

4

1 reference

24 September 2017

Makoto Arai

5

1 reference

24 September 2017

Masanari Itokawa

6

1 reference

24 September 2017

Raju Kucherlapati

7

1 reference

24 September 2017

Takehito Sawamura

9

1 reference

24 September 2017

Soh Agatsuma

10

1 reference

24 September 2017

language of work or name

English

0 references

publication date

19 December 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

24 September 2017

1 reference

24 September 2017

102

1 reference

24 September 2017

52

1 reference

24 September 2017

19132-19137

1 reference

Lower prepulse inhibition in children with the 22q11 deletion syndrome

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Microduplication and triplication of 22q11.2: a highly variable syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Identification of a novel nuclear localization signal in Tbx1 that is deleted in DiGeorge syndrome patients harboring the 1223delC mutation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Tbx1 is required for proper neural crest migration and to stabilize spatial patterns during middle and inner ear development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

The molecular genetics of the 22q11-associated schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

The del22q11.2 candidate gene Tbx1 regulates branchiomeric myogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Glutamate as a therapeutic target in psychiatric disorders

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

MAO-B knockout mice exhibit deficient habituation of locomotor activity but normal nicotine intake

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Full spectrum of malformations in velo-cardio-facial syndrome/DiGeorge syndrome mouse models by altering Tbx1 dosage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

A new genomic duplication syndrome complementary to the velocardiofacial (22q11 deletion) syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Suppression of neural fate and control of inner ear morphogenesis by Tbx1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Role of TBX1 in human del22q11.2 syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Microduplication 22q11.2, an emerging syndrome: clinical, cytogenetic, and molecular analysis of thirteen patients

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

The schizophrenia phenotype in 22q11 deletion syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

TBX1 is required for inner ear morphogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Association between a functional catechol O-methyltransferase gene polymorphism and schizophrenia: meta-analysis of case-control and family-based studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Dopamine D2S and D2L receptors may differentially contribute to the actions of antipsychotic and psychotic agents in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Neuregulin 1 and susceptibility to schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

A systems model of altered consciousness: integrating natural and drug-induced psychoses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor epsilon1 subunit

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Behavioural pharmacology of the new generation of antipsychotic agents

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Neurobiological basis of relapse prediction in stimulant-induced psychosis and schizophrenia: the role of sensitization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Mice with reduced NMDA receptor expression display behaviors related to schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

A common molecular basis for rearrangement disorders on chromosome 22q11

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Antipsychotics from theory to practice: integrating clinical and basic data

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

The gene encoding proline dehydrogenase modulates sensorimotor gating in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Clinical characteristics of schizophrenia associated with velo-cardio-facial syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Molecular analysis of velo-cardio-facial syndrome patients with psychiatric disorders.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Bipolar spectrum disorders in patients diagnosed with velo-cardio-facial syndrome: does a hemizygous deletion of chromosome 22q11 result in bipolar affective disorder?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Child development risk factors for adult schizophrenia in the British 1946 birth cohort

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Childhood antecedents of schizophrenia and affective illness: social adjustment at ages 7 and 11

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Response to divergent selection for nesting behavior in Mus musculus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

High rates of schizophrenia in adults with velo-cardio-facial syndrome.

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509635102

22q11.2 duplication syndrome: two new familial cases with some overlapping features with DiGeorge/velocardiofacial syndromes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509635102

Multicenter linkage study of schizophrenia loci on chromosome 22q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509635102

Mice deleted for the DiGeorge/velocardiofacial syndrome region show abnormal sensorimotor gating and learning and memory impairments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509635102

Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509635102

Mice overexpressing genes from the 22q11 region deleted in velo-cardio-facial syndrome/DiGeorge syndrome have middle and inner ear defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509635102

Chronic low dose risperidone and clozapine alleviate positive but not negative symptoms in the rat neonatal ventral hippocampal lesion model of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509635102

Neuropharmacological profile of a novel potential atypical antipsychotic drug Y-931 (8-fluoro-12-(4-methylpiperazin-1-yl)- 6H-[1]benzothieno[2,3-b][1,5] benzodiazepine maleate).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509635102

Velocardiofacial syndrome in childhood-onset schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509635102

Evaluation of dopamine D-2 receptor occupancy by clozapine, risperidone, and haloperidol in vivo in the rodent and nonhuman primate brain using 18F-fallypride

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509635102

Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: a suggested solution based on in vivo occupancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509635102

Mice lacking leukocyte common antigen-related (LAR) protein tyrosine phosphatase domains demonstrate spatial learning impairment in the two-trial water maze and hyperactivity in multiple behavioural tests

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509635102

Schizophrenia: the fundamental questions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509635102

Obsessive-compulsive disorder in patients with velocardiofacial (22q11 deletion) syndrome

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Severe impairment of NMDA receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant nonhabituating hyperactivity.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Tissue concentrations of clozapine and its metabolites in the rat

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Psychotic illness in patients diagnosed with velo-cardio-facial syndrome and their relatives

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323212

Late‐Onset psychosis in the velo‐cardio‐facial syndrome

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16365290

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A comparison between house mouse lines selected for attack latency or nest-building: evidence for a genetic basis of alternative behavioral strategies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16365290

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Blockade of phencyclidine-induced hyperlocomotion by olanzapine, clozapine and serotonin receptor subtype selective antagonists in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16365290

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0509635102

1 reference

24 September 2017

0 references

1 reference

24 September 2017

1 reference