Structure and kinetics of a transient antibody binding intermediate reveal a kinetic discrimination mechanism in antigen recognition (Q30476133)

11 November 2017

Structure and kinetics of a transient antibody binding intermediate reveal a kinetic discrimination mechanism in antigen recognition (English)

1 reference

11 November 2017

1 reference

Leo C James

1

1 reference

PMCID

1200256

11 November 2017

Dan S Tawfik

series ordinal

2

1 reference

PMCID

1200256

11 November 2017

language of work or name

English

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publication date

29 August 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

11 November 2017

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11 November 2017

102

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11 November 2017

12730-12735

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11 November 2017

36

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The CCP4 suite: programs for protein crystallography

11 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

Conformational changes associated with protein-protein interactions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

X-ray snapshots of the maturation of an antibody response to a protein antigen

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

Antibody multispecificity mediated by conformational diversity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

Extraordinarily slow binding of guanosine to the Tetrahymena group I ribozyme: implications for RNA preorganization and function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

Molecular recognition in antibody-antigen complexes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

G protein mechanisms: insights from structural analysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

Shape complementarity at protein/protein interfaces

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

Major antigen-induced domain rearrangements in an antibody

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

Conformational isomerism and the diversity of antibodies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

Antibody-antigen interactions: new structures and new conformational changes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

Kinetic maturation of an immune response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

Mechanism of allergic cross-reactions—I. Multispecific binding of ligands to a mouse monoclonal anti-DNP IgE antibody

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

Structural evidence for induced fit as a mechanism for antibody-antigen recognition

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1200256

T cell receptors: affinities, cross-reactivities, and a conformer model

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500909102

"Induced-fit" mechanism for catecholamine binding to the beta2-adrenergic receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500909102

The specificity of cross‐reactivity: Promiscuous antibody binding involves specific hydrogen bonds rather than nonspecific hydrophobic stickiness

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500909102

The morph server: a standardized system for analyzing and visualizing macromolecular motions in a database framework

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500909102

Protein dynamics and the immunological evolution of molecular recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500909102

Flexibility and molecular recognition in the immune system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500909102

Early high-affinity neutralizing anti-viral IgG responses without further overall improvements of affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500909102

A very high level of crossreactivity is an essential feature of the T-cell receptor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16129832

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Maturation of an antibody response is governed by modulations in flexibility of the antigen-combining site

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16129832

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0500909102

1 reference

11 November 2017

0 references

1 reference

11 November 2017

1 reference

PMCID

1200256