Theragnostics for tumor and plaque angiogenesis with perfluorocarbon nanoemulsions (Q30474759)

14 October 2017

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title

Theragnostics for tumor and plaque angiogenesis with perfluorocarbon nanoemulsions (English)

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14 October 2017

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2

P M Winter

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14 October 2017

G M Lanza

1

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14 October 2017

S D Caruthers

3

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14 October 2017

M S Hughes

4

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14 October 2017

Grace Hu

5

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14 October 2017

A H Schmieder

6

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14 October 2017

S A Wickline

7

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14 October 2017

language of work or name

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22 April 2010

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14 October 2017

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14 October 2017

13

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14 October 2017

2

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14 October 2017

189-202

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https://scigraph.springernature.com/pub.10.1007/s10456-010-9166-0

14 October 2017

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20 June 2018

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20 June 2018

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AG-013736, a novel inhibitor of VEGF receptor tyrosine kinases, inhibits breast cancer growth and decreases vascular permeability as detected by dynamic contrast-enhanced magnetic resonance imaging

20 June 2018

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Evaluation of a (99m)Tc-labeled cyclic RGD tetramer for noninvasive imaging integrin alpha(v)beta3-positive breast cancer

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20 June 2018

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The clinical toxicity profile of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) targeting angiogenesis inhibitors; a review

20 June 2018

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Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker

20 June 2018

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Neovascularization in human atherosclerosis

20 June 2018

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20 June 2018

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Sonic activation of molecularly-targeted nanoparticles accelerates transmembrane lipid delivery to cancer cells through contact-mediated mechanisms: implications for enhanced local drug delivery

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20 June 2018

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20 June 2018

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Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy

20 June 2018

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The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations.

20 June 2018

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Quantitative "magnetic resonance immunohistochemistry" with ligand-targeted (19)F nanoparticles.

20 June 2018

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Evaluation of 64Cu- and 125I-radiolabeled bitistatin as potential agents for targeting alpha v beta 3 integrins in tumor angiogenesis

20 June 2018

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18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis

20 June 2018

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The Homeobox Transcription Factor Hox D3 Promotes Integrin α5β1 Expression and Function during Angiogenesis

20 June 2018

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20 June 2018

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Improvements in the ultrasonic contrast of targeted perfluorocarbon nanoparticles using an acoustic transmission line model.

20 June 2018

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20 June 2018

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20 June 2018

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Regulation of integrin alpha vbeta 3-mediated endothelial cell migration and angiogenesis by integrin alpha5beta1 and protein kinase A.

20 June 2018

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20 June 2018

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Regression of metastatic breast cancer in a patient treated with the anti-angiogenic drug TNP-470.

20 June 2018

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Effects of angiogenesis inhibitors on multistage carcinogenesis in mice

20 June 2018

1 reference

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Structure of human methionine aminopeptidase-2 complexed with fumagillin

20 June 2018

1 reference

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Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors

20 June 2018

1 reference

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The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

20 June 2018

1 reference

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TNP-470 (AGM-1470): mechanisms of action and early clinical development.

20 June 2018

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The potential role of perfluorochemicals (PFCs) in diagnostic imaging

20 June 2018

1 reference

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Granulocyte-macrophage and macrophage colony-stimulating factors differentially regulate alpha v integrin expression on cultured human macrophages

20 June 2018

1 reference

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Tumor angiogenesis: therapeutic implications

20 June 2018

1 reference

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20 June 2018

1 reference

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MicroPET imaging of brain tumor angiogenesis with 18F-labeled PEGylated RGD peptide

20 June 2018

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FDA approves sorafenib for patients with inoperable liver cancer

21 January 2018

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26 November 2018

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26 November 2018

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Statin treated patients have reduced intraplaque angiogenesis in carotid endarterectomy specimens.

26 November 2018

1 reference

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26 November 2018

1 reference

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Food and Drug Administration drug approval summary: Sunitinib malate for the treatment of gastrointestinal stromal tumor and advanced renal cell carcinoma.

26 November 2018

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In vitro demonstration using 19F magnetic resonance to augment molecular imaging with paramagnetic perfluorocarbon nanoparticles at 1.5 Tesla

26 November 2018

1 reference

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MR molecular imaging and fluorescence microscopy for identification of activated tumor endothelium using a bimodal lipidic nanoparticle.

26 November 2018

1 reference

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26 November 2018

1 reference

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26 November 2018

1 reference

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26 November 2018

1 reference

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Plaque Neovascularization Is Increased in Ruptured Atherosclerotic Lesions of Human Aorta

26 November 2018

1 reference

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26 November 2018

1 reference

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90Y and 111In complexes of a DOTA-conjugated integrin alpha v beta 3 receptor antagonist: different but biologically equivalent

26 November 2018

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Vascular oxidant stress enhances progression and angiogenesis of experimental atheroma

26 November 2018

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Pharmacokinetics and tumor retention of 125I-labeled RGD peptide are improved by PEGylation

26 November 2018

1 reference

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MicroPET and autoradiographic imaging of breast cancer alpha v-integrin expression using 18F- and 64Cu-labeled RGD peptide

26 November 2018

1 reference

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Molecular imaging of angiogenesis in early-stage atherosclerosis with alpha(v)beta3-integrin-targeted nanoparticles

26 November 2018

1 reference

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Tumor targeting with radiolabeled alpha(v)beta(3) integrin binding peptides in a nude mouse model.

26 November 2018

1 reference

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Statins reduce inflammation in atheroma of nonhuman primates independent of effects on serum cholesterol

26 November 2018

1 reference

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26 November 2018

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Phase I trial of the angiogenesis inhibitor TNP-470 for progressive androgen-independent prostate cancer.

26 November 2018

1 reference

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Size optimization of synthetic graft copolymers for in vivo angiogenesis imaging

26 November 2018

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Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size

26 November 2018

1 reference

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A Phase I and pharmacokinetic study of TNP-470 administered weekly to patients with advanced cancer.

26 November 2018

1 reference

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In vitro characterization of a novel, tissue-targeted ultrasonic contrast system with acoustic microscopy.

26 November 2018

1 reference

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Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging

26 November 2018

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Expression and localization of alpha v integrins and their ligand vitronectin in normal ovarian epithelium and in ovarian carcinoma

26 November 2018

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12 December 2020

Molecular imaging of angiogenesis in nascent Vx-2 rabbit tumors using a novel alpha(nu)beta3-targeted nanoparticle and 1.5 tesla magnetic resonance imaging

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12 December 2020

Radiolabeled alpha(v)beta3 integrin antagonists: a new class of tracers for tumor targeting

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12 December 2020

Complete remission of metastatic cervical cancer with the angiogenesis inhibitor TNP-470

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12 December 2020

Leucocyte recruitment in rupture prone regions of lipid-rich plaques: a prominent role for neovascularization?

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12 December 2020

Fibrin-targeted perfluorocarbon nanoparticles for targeted thrombolysis

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12 December 2020

The angiogenesis inhibitor tnp-470 effectively inhibits human neuroblastoma xenograft growth, especially in the setting of subclinical disease

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12 December 2020

Differential clinical significance of alpha(v)Beta(3) expression in primary lesions of acral lentiginous melanoma and of other melanoma histotypes

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12 December 2020

Temperature dependence of ultrasonic enhancement with a site-targeted contrast agent

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12 December 2020

ACC/AHA/NHLBI Clinical Advisory on the Use and Safety of Statins

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12 December 2020

The activation state of alphavbeta 3 regulates platelet and lymphocyte adhesion to intact and thrombin-cleaved osteopontin

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12 December 2020

Experimental determination of phase velocity of perfluorocarbons: applications to targeted contrast agents

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12 December 2020

A phase I study of TNP-470 administered to patients with advanced squamous cell cancer of the cervix

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12 December 2020

The role of integrins in saphenous vein vascular smooth muscle cell migration

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12 December 2020

Expression of angiogenic factor thymidine phosphorylase and angiogenesis in human atherosclerosis

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12 December 2020

Statin treatment is not associated with consistent alterations in inflammatory status of carotid atherosclerotic plaques: a retrospective study in 378 patients undergoing carotid endarterectomy

1 reference

12 December 2020

Perfluoroctylbromide: a liver/spleen-specific and tumor-imaging ultrasound contrast material

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12 December 2020

Efficacy of an angiogenesis inhibitor, TNP-470, in xenotransplanted human colorectal cancer with high metastatic potential

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12 December 2020

Eliminating plaque angiogenesis

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12 December 2020

FDA drug approval summary: bevacizumab plus FOLFOX4 as second-line treatment of colorectal cancer

1 reference

12 December 2020

A novel site-targeted ultrasonic contrast agent with broad biomedical application

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12 December 2020

Evidence of hypoxic areas within the arterial wall in vivo

1 reference

12 December 2020

Endothelial alpha(v)beta3 integrin-targeted fumagillin nanoparticles inhibit angiogenesis in atherosclerosis

1 reference

12 December 2020

Targeted antiproliferative drug delivery to vascular smooth muscle cells with a magnetic resonance imaging nanoparticle contrast agent: implications for rational therapy of restenosis

1 reference

12 December 2020

Simvastatin decreases aldehyde production derived from lipoprotein oxidation

1 reference

12 December 2020

Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition

1 reference

12 December 2020

Effects of fluvastatin on leukocyte-endothelial cell adhesion in hypercholesterolemic rats

1 reference

12 December 2020

10.1007/S10456-010-9166-0

Identifiers

DOI

1 reference

14 October 2017

1 reference

14 October 2017

1 reference