Akt1 deficiency in schizophrenia and impairment of hippocampal plasticity and function (Q30458585)

20 September 2017

Akt1 deficiency in schizophrenia and impairment of hippocampal plasticity and function (English)

1 reference

20 September 2017

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7

1 reference

20 September 2017

Darrick T Balu

1

1 reference

ORCID Public Data File 2021

author name string

Gregory C Carlson

2

1 reference

20 September 2017

Konrad Talbot

3

1 reference

20 September 2017

Hala Kazi

4

1 reference

20 September 2017

Tiffany E Hill-Smith

5

1 reference

20 September 2017

Rachel M Easton

6

1 reference

20 September 2017

Irwin Lucki

8

1 reference

20 September 2017

3 November 2010

1 reference

20 September 2017

1 reference

20 September 2017

22

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20 September 2017

2

1 reference

20 September 2017

230-240

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Adult-born hippocampal neurons are more numerous, faster maturing, and more involved in behavior in rats than in mice

20 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Flow cytometric analysis of BrdU incorporation as a high-throughput method for measuring adult neurogenesis in the mouse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Akt/GSK3 signaling in the action of psychotropic drugs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Adult hippocampal neurogenesis: regulation, functional implications, and contribution to disease pathology

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Large recurrent microdeletions associated with schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Rare chromosomal deletions and duplications increase risk of schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Spatial relational memory requires hippocampal adult neurogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Mechanisms and functional implications of adult neurogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Neuroplasticity of neocortical circuits in schizophrenia.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

The cognitive neuroscience of schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

AKT/PKB signaling: navigating downstream

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Physiological roles of PKB/Akt isoforms in development and disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

The role of the phosphatidylinositide 3-kinase-protein kinase B pathway in schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Absence of significant associations between four AKT1 SNP markers and schizophrenia in the Taiwanese population

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

The hippocampus in schizophrenia: a review of the neuropathological evidence and its pathophysiological implications

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Hippocampal modulation of sensorimotor processes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Cognitive function in schizophrenia. Deficits, functional consequences, and future treatment

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

The place of the hippocampus in fear conditioning

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Trk receptors: mediators of neurotrophin action

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Modulation of the startle response and startle laterality in relatives of schizophrenic patients and in subjects with schizotypal personality disorder: evidence of inhibitory deficits

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Cell biology of the hippocampal formation in schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Novel expression mechanism for synaptic potentiation: alignment of presynaptic release site and postsynaptic receptor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

20 June 2018

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.20887

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.20887

Impairment on the hippocampal-dependent virtual Morris water task in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.20887

Ipsilateral associational pathway in the dentate gyrus: an excitatory feedback system that supports N-methyl-D-aspartate-dependent long-term potentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.20887

Signalling mechanisms mediated by the phosphoinositide 3-kinase/Akt cascade in synaptic plasticity and memory in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.20887

Failure to support a genetic contribution of AKT1 polymorphisms and altered AKT signaling in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.20887

Cyclin-dependent kinase-5 is involved in neuregulin-dependent activation of phosphatidylinositol 3-kinase and Akt activity mediating neuronal survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.20887

Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.20887

Neural stem cell proliferation is decreased in schizophrenia, but not in depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.20887

Inhibition of neurogenesis interferes with hippocampus-dependent memory function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.20887

Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.20887

The role of DTNBP1, NRG1, and AKT1 in the genetics of schizophrenia in Finland

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.20887

Association of AKT1 gene polymorphisms with risk of schizophrenia and with response to antipsychotics in the Chinese population

21 January 2018

2 references

https://api.crossref.org/works/10.1002%2FHIPO.20887

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258343

Association of AKT1 haplotype with the risk of schizophrenia in Iranian population

26 November 2018

1 reference

12 December 2020

Neurobiology of schizophrenia

1 reference

12 December 2020

Failure to confirm association between AKT1 haplotype and schizophrenia in a Japanese case-control population

1 reference

12 December 2020

Association of AKT1 with schizophrenia confirmed in a Japanese population

1 reference

12 December 2020

Further evidence for association of variants in the AKT1 gene with schizophrenia in a sample of European sib-pair families

1 reference

12 December 2020

Identifiers

DOI

10.1002/HIPO.20887

1 reference

20 September 2017

1 reference

20 September 2017

1 reference