Inhibition of telomerase recruitment and cancer cell death (Q30457044)

19 August 2017

Inhibition of telomerase recruitment and cancer cell death (English)

1 reference

19 August 2017

1 reference

Jayakrishnan Nandakumar

object named as

Jayakrishnan Nandakumar

series ordinal

2

0 references

Kelly D Sullivan

object named as

Kelly D Sullivan

series ordinal

3

0 references

Thomas Cech

series ordinal

5

object named as

Thomas R Cech

1 reference

19 August 2017

4

Joaquín M Espinosa

1 reference

19 August 2017

Mai Nakashima

1

1 reference

PMCID

3829164

19 August 2017

language of work or name

English

0 references

publication date

4 October 2013

1 reference

Journal of Biological Chemistry

19 August 2017

1 reference

19 August 2017

288

1 reference

19 August 2017

46

1 reference

19 August 2017

33171-33180

1 reference

PMCID

3829164

describes a project that uses

19 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3829164/fullTextXML

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3829164/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Highly prevalent TERT promoter mutations in aggressive thyroid cancers

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829164

Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss

20 June 2018

1 reference

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TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829164

Highly recurrent TERT promoter mutations in human melanoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829164

TERT promoter mutations in familial and sporadic melanoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829164

Finding the end: recruitment of telomerase to telomeres

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829164

The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829164

Specificity requirements for human telomere protein interaction with telomerase holoenzyme

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829164

TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends

20 June 2018

1 reference

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TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829164

POT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829164

A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis

20 June 2018

1 reference

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How shelterin protects mammalian telomeres

20 June 2018

1 reference

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TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829164

Selective cytotoxicity and telomere damage in leukemia cells using the telomerase inhibitor BIBR1532.

20 June 2018

1 reference

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DNA damage foci at dysfunctional telomeres

20 June 2018

1 reference

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Induction of apoptosis by telomere 3' overhang-specific DNA.

20 June 2018

1 reference

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Mechanism of human telomerase inhibition by BIBR1532, a synthetic, non-nucleosidic drug candidate.

20 June 2018

1 reference

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A highly selective telomerase inhibitor limiting human cancer cell proliferation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829164

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829164

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829164

Reverse transcriptase motifs in the catalytic subunit of telomerase

20 June 2018

1 reference

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Specific association of human telomerase activity with immortal cells and cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829164

Telomere end-replication problem and cell aging

20 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M113.518175

Highly prevalent TERT promoter mutations in bladder cancer and glioblastoma

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M113.518175

Human telomerase RNA accumulation in Cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24097987

12 December 2020

inferred from PubMed ID database lookup

Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24097987

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M113.518175

1 reference

19 August 2017

1 reference

19 August 2017

1 reference

PMCID

3829164