Dichloroacetate inhibits glycolysis and augments insulin-stimulated glycogen synthesis in rat muscle (Q30449376)

24 September 2017

Dichloroacetate inhibits glycolysis and augments insulin-stimulated glycogen synthesis in rat muscle (English)

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24 September 2017

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A S Clark

1

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24 September 2017

W E Mitch

2

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24 September 2017

M N Goodman

3

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24 September 2017

J M Fagan

4

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24 September 2017

M A Goheer

5

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24 September 2017

R T Curnow

6

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24 September 2017

language of work or name

English

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publication date

1 February 1987

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Journal of Clinical Investigation

24 September 2017

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24 September 2017

79

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24 September 2017

2

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24 September 2017

588-594

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Branched-chain amino acid metabolism and alanine formation in rat diaphragm muscle in vitro. Effects of dichloroacetate

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Systemic response to thermal injury in rats. Accelerated protein degradation and altered glucose utilization in muscle

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Lactate metabolism in the perfused rat hindlimb

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

The rate of substrate cycling between fructose 6-phosphate and fructose 1,6-bisphosphate in skeletal muscle

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Muscle protein turnover and glucose uptake in acutely uremic rats. Effects of insulin and the duration of renal insufficiency

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Comparison of protein synthesis and degradation in incubated and perfused muscle

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Treatment of Lactic Acidosis with Dichloroacetate in Dogs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

The effects of starvation and alloxan-diabetes on the contents of citrate and other metabolic intermediates in rat liver

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Effects of dichloroacetate on the metabolism of glucose, pyruvate, acetate, 3-hydroxybutyrate and palmitate in rat diaphragm and heart muscle in vitro and on extraction of glucose, lactate, pyruvate and free fatty acids by dog heart in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

The pentose cycle and insulin release in mouse pancreatic islets

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Mechanism of activation of pyruvate dehydrogenase by dichloroacetate and other halogenated carboxylic acids

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Effects of dichloroacetate in the treatment of hypoxic lactic acidosis in dogs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Selectivity of the insulin-like actions of vanadate on glucose and protein metabolism in skeletal muscle

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Specific defects in insulin-mediated muscle metabolism in acute uremia.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Glucose and amino acid metabolism in perfused skeletal muscle. Effect of dichloroacetate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Mechanism responsible for the hypoglycemic actions of dichloroacetate and 2-chloropropionate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Glycogen synthesis from lactate in the three types of skeletal muscle

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Recycling of Glucose by Rat Hepatocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Metabolic interactions of dichloroacetate and insulin in experimental diabetic ketoacidosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Rabbit skeletal muscle glycogen synthase. II. Enzyme phosphorylation state and effector concentrations as interacting control parameters

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Estimation of the fructose diphosphatase-phosphofructokinase substrate cycle in the flight muscle of Bombus affinis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424134

Contribution of the liver and extrasplanchnic tissues to the hypoglycemic action of dichloroacetate in the conscious dog

26 November 2018

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12 December 2020

Effect of dichloroacetate on gluconeogenesis in isolated rat hepatocytes

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12 December 2020

The regulation of pyruvate dehydrogenase in the isolated perfused rat heart

1 reference

12 December 2020

Estimation of pyruvate decarboxylation in perfused rat skeletal muscle

1 reference

12 December 2020

1 reference

12 December 2020

Radioactive method for the assay of glycogen phosphorylases

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12 December 2020

Treatment of lactic acidosis with dichloroacetate

1 reference

12 December 2020

Prolonged hypolactatemia and increased total pyruvate dehydrogenase activity by dichloroacetate

1 reference

12 December 2020

Effect of dichloroacetate on gluconeogenesis in vivo in the presence of a fixed gluconeogenic substrate supply to the liver

1 reference

12 December 2020

Therapeutic benefit of dichloroacetate in experimentally induced hypoxic lactic acidosis

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12 December 2020

Product Inhibition of the Hexokinases

1 reference

12 December 2020

Metabolic effects and pharmacokinetics of intravenously administered dichloroacetate in humans

1 reference

12 December 2020

Glucose-2-t as a Tracer for Glucose Metabolism*

1 reference

12 December 2020

A rapid filter paper assay for UDPglucose-glycogen glucosyltransferase, including an improved biosynthesis of UDP-14C-glucose

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI112851

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24 September 2017

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24 September 2017

PubMed publication ID

3543056

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