Blocking the immune response in ischemic acute kidney injury: the role of adenosine 2A agonists (Q30441415)

21 June 2017

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title

Blocking the immune response in ischemic acute kidney injury: the role of adenosine 2A agonists (English)

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21 June 2017

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1

Li Li

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21 June 2017

2

Mark D Okusa

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21 June 2017

1 August 2006

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Nature Clinical Practice Nephrology

21 June 2017

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21 June 2017

2

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21 June 2017

432-444

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21 June 2017

8

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The pathophysiological implications of medullary hypoxia

21 June 2017

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

A2A adenosine receptor induction inhibits IFN-gamma production in murine CD4+ T cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

Injury in renal ischemia-reperfusion is independent from immunoglobulins and T lymphocytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: the role of CD4+ T cells and IFN-gamma

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

B cell deficiency confers protection from renal ischemia reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

Mature dendritic cells derived from human monocytes within 48 hours: a novel strategy for dendritic cell differentiation from blood precursors

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

TNF skews monocyte differentiation from macrophages to dendritic cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

The Ly-6Chigh monocyte subpopulation transports Listeria monocytogenes into the brain during systemic infection of mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

Vasoconstrictor and vasodilator effects of adenosine in the kidney.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

Region-specific alterations of adenosine receptors expression level in kidney of diabetic rat.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

Ligand-activation of the adenosine A2a receptors inhibits IL-12 production by human monocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

Adenosine attenuates oxidant injury in human proximal tubular cells via A(1) and A(2a) adenosine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

Recent advances in the pathophysiology of ischemic acute renal failure

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Hospital-acquired renal insufficiency

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

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Treatment of acute renal failure

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7 January 2021

Independent association between acute renal failure and mortality following cardiac surgery

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7 January 2021

Prevention of contrast-induced nephropathy with sodium bicarbonate: a randomized controlled trial

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7 January 2021

Comparison of two hemofiltration protocols for prevention of contrast-induced nephropathy in high-risk patients.

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7 January 2021

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

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7 January 2021

Is acetylcysteine effective in preventing contrast-related nephropathy? A meta-analysis.

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Acute renal failure: definitions, diagnosis, pathogenesis, and therapy

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Microvascular endothelial injury and dysfunction during ischemic acute renal failure.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

The inflammatory cascade in acute ischemic renal failure

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Osteogenic protein-1 (bone morphogenetic protein-7) reduces severity of injury after ischemic acute renal failure in rat.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

EPO and alpha-MSH prevent ischemia/reperfusion-induced down-regulation of AQPs and sodium transporters in rat kidney

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Monocyte and macrophage heterogeneity

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

The T cell as a bridge between innate and adaptive immune systems: implications for the kidney

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Signaling danger: toll-like receptors and their potential roles in kidney disease

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Innate immune recognition

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Blood monocytes consist of two principal subsets with distinct migratory properties

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Immunobiology of dendritic cells

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Dendritic cells: specialized and regulated antigen processing machines

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Alpha-melanocyte-stimulating hormone protects against renal injury after ischemia in mice and rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Inflammatory cells in ischemic acute renal failure

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Alpha-melanocyte-stimulating hormone inhibits renal injury in the absence of neutrophils

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Blocking P-selectin protects from ischemia/reperfusion-induced acute renal failure.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney. Inhibition by a soluble P-selectin ligand

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Effects of combined T- and B-cell deficiency on murine ischemia reperfusion injury

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Peripheral CD4 T-cell depletion is not sufficient to prevent ischemic acute renal failure

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Cold liver ischemia-reperfusion injury critically depends on liver T cells and is improved by donor pretreatment with interleukin 10 in mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Cytotoxic T lymphocytes are activated following myocardial infarction and can recognize and kill healthy myocytes in vitro

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

CD4(+) T-lymphocytes mediate ischemia/reperfusion-induced inflammatory responses in mouse liver

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Identification of the CD4(+) T cell as a major pathogenic factor in ischemic acute renal failure

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

CD28-b7 blockade in organ dysfunction secondary to cold ischemia/reperfusion injury

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

CC chemokine receptor 7-dependent and -independent pathways for lymphocyte homing: modulation by FTY720.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

The NKT cell system: bridging innate and acquired immunity

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Macrophages and the kidney

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

A Clonogenic Bone Marrow Progenitor Specific for Macrophages and Dendritic Cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Interferon-gamma switches monocyte differentiation from dendritic cells to macrophages

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

IL-6 switches the differentiation of monocytes from dendritic cells to macrophages

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Multiple facets of macrophages in renal injury

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

CCR2 signaling contributes to ischemia-reperfusion injury in kidney

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Macrophages contribute to the initiation of ischaemic acute renal failure in rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Dendritic cell maturation by innate lymphocytes: coordinated stimulation of innate and adaptive immunity

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Alternative activation of macrophages

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

The crucial role of macrophages in lymphangiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow-derived cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Prominent and sustained up-regulation of gp130-signaling cytokines and the chemokine MIP-2 in murine renal ischemia-reperfusion injury

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Antigen presentation by dendritic cells in renal lymph nodes is linked to systemic and local injury to the kidney.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Role of the T-cell receptor in kidney ischemia-reperfusion injury

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Interactions between human mesenchymal stem cells and natural killer cells

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7 January 2021

Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells

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7 January 2021

A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Design, synthesis, and evaluation of novel A2A adenosine receptor agonists

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Gene expression of adenosine receptors along the nephron

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Paracrine regulation of the renal microcirculation

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Adenosine signaling in outer medullary descending vasa recta

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

A(2A) adenosine receptors in human peripheral blood cells

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

Molecular approach to adenosine receptors: receptor-mediated mechanisms of tissue protection

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7 January 2021

A1 adenosine receptor activation inhibits inflammation, necrosis, and apoptosis after renal ischemia-reperfusion injury in mice

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https://api.crossref.org/works/10.1038%2FNCPNEPH0238

7 January 2021

The 'danger' sensors that STOP the immune response: the A2 adenosine receptors?

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7 January 2021

Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage

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7 January 2021

Cyclic AMP-dependent inhibition of human neutrophil oxidative activity by substituted 2-propynylcyclohexyl adenosine A(2A) receptor agonists

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7 January 2021

Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors

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7 January 2021

Adenosine A2A agonists in development for the treatment of inflammation

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7 January 2021

Neutrophil A2A adenosine receptor inhibits inflammation in a rat model of meningitis: synergy with the type IV phosphodiesterase inhibitor, rolipram

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7 January 2021

Activation of A2A adenosine receptors inhibits expression of alpha 4/beta 1 integrin (very late antigen-4) on stimulated human neutrophils

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7 January 2021

Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms

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7 January 2021

T-cell costimulatory pathways in allograft rejection and tolerance

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cAMP inhibits induction of interleukin 2 but not of interleukin 4 in T cells

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7 January 2021

Adenosine response of the rat kidney after saline loading, sodium restriction and hemorrhagia

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7 January 2021

Systemic adenosine given after ischemia protects renal function via A(2a) adenosine receptor activation

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7 January 2021

Reduction of infarct size and postischemic inflammation from ATL-146e, a highly selective adenosine A2A receptor agonist, in reperfused canine myocardium

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7 January 2021

Selective adenosine-A2A activation reduces lung reperfusion injury following transplantation.

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7 January 2021

Adenosine A2A analogue reduces long-term neurologic injury after blunt spinal trauma

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7 January 2021

Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease

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7 January 2021

The many roles of chemokines and chemokine receptors in inflammation

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7 January 2021

Identifiers

DOI

10.1038/NCPNEPH0238

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21 June 2017

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PubMed ID

16932478