Pdx1 and BETA2/NeuroD1 participate in a transcriptional complex that mediates short-range DNA looping at the insulin gene (Q30439989)

14 August 2017

Pdx1 and BETA2/NeuroD1 participate in a transcriptional complex that mediates short-range DNA looping at the insulin gene (English)

1 reference

14 August 2017

Daniella A Babu

1

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14 August 2017

Swarup K Chakrabarti

series ordinal

2

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14 August 2017

James C Garmey

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3

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14 August 2017

Raghavendra G Mirmira

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4

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14 August 2017

language of work or name

English

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publication date

4 February 2008

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Journal of Biological Chemistry

14 August 2017

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14 August 2017

283

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13

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8164-8172

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describes a project that uses

14 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2276387/fullTextXML

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inferred from PubMed Central ID database lookup

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2276387/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis

14 July 2018

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Role of chromatin accessibility in the occupancy and transcription of the insulin gene by the pancreatic and duodenal homeobox factor 1.

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Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription

14 July 2018

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Histone modifications defining active genes persist after transcriptional and mitotic inactivation

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Proendocrine genes coordinate the pancreatic islet differentiation program in vitro

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Acetylation of the BETA2 transcription factor by p300-associated factor is important in insulin gene expression

14 July 2018

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Transcription factors direct the development and function of pancreatic beta cells

14 July 2018

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Looping and interaction between hypersensitive sites in the active beta-globin locus

14 July 2018

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Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding

14 July 2018

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Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47.

14 July 2018

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CREB-binding protein and p300 in transcriptional regulation

14 July 2018

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14 July 2018

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Transcription factor BETA2 acts cooperatively with E2A and PDX1 to activate the insulin gene promoter

14 July 2018

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The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter

14 July 2018

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Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus

14 July 2018

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Glucose stimulates translocation of the homeodomain transcription factor PDX1 from the cytoplasm to the nucleus in pancreatic beta-cells

14 July 2018

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p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene

14 July 2018

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Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

14 July 2018

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Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1

14 July 2018

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PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

14 July 2018

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Insulin-promoter-factor 1 is required for pancreas development in mice

14 July 2018

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Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor

14 July 2018

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Murine pancreatic ductal adenocarcinoma produced by in vitro transduction of polyoma middle T oncogene into the islets of Langerhans

14 July 2018

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A mutational analysis of the insulin gene transcription control region: expression in beta cells is dependent on two related sequences within the enhancer

14 July 2018

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Neogenesis of beta-cells in adult BETA2/NeuroD-deficient mice

14 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M800336200

21 January 2018

Identifiers

DOI

10.1074/JBC.M800336200

1 reference

14 August 2017

1 reference

14 August 2017

1 reference