Calorie restriction effects on silencing and recombination at the yeast rDNA. (Q30430955)

1 September 2017

Calorie restriction effects on silencing and recombination at the yeast rDNA. (English)

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1 September 2017

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Daniel L Smith

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1 September 2017

Chonghua Li

2

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1 September 2017

Mirela Matecic

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1 September 2017

Nazif Maqani

4

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1 September 2017

Mary Bryk

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1 September 2017

Jeffrey S Smith

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1 September 2017

2 September 2009

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1 September 2017

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1 September 2017

6

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1 September 2017

633-642

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describes a project that uses

1 September 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3163344/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Pnc1p-mediated nicotinamide clearance modifies the epigenetic properties of rDNA silencing in Saccharomyces cerevisiae

20 June 2018

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Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

20 June 2018

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SirT1 regulates energy metabolism and response to caloric restriction in mice

20 June 2018

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MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae.

20 June 2018

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Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress

20 June 2018

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SIRT1 transgenic mice show phenotypes resembling calorie restriction

20 June 2018

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Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins

20 June 2018

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Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression

20 June 2018

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Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans

20 June 2018

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Dietary deprivation extends lifespan in Caenorhabditis elegans

20 June 2018

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Sir2 represses endogenous polymerase II transcription units in the ribosomal DNA nontranscribed spacer

20 June 2018

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Extension of chronological life span in yeast by decreased TOR pathway signaling

20 June 2018

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Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

20 June 2018

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Sir2 blocks extreme life-span extension.

20 June 2018

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Recombination Regulation by Transcription-Induced Cohesin Dissociation in rDNA Repeats

20 June 2018

1 reference

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HST2 mediates SIR2-independent life-span extension by calorie restriction

20 June 2018

1 reference

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Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition

20 June 2018

1 reference

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Substrate-specific activation of sirtuins by resveratrol

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Sir2-independent life span extension by calorie restriction in yeast

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

20 June 2018

1 reference

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Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Calorie restriction extends yeast life span by lowering the level of NADH.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Genetics: influence of TOR kinase on lifespan in C. elegans

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Association of the RENT complex with nontranscribed and coding regions of rDNA and a regional requirement for the replication fork block protein Fob1 in rDNA silencing

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

RNA polymerase I propagates unidirectional spreading of rDNA silent chromatin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

High osmolarity extends life span in Saccharomyces cerevisiae by a mechanism related to calorie restriction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Identification and functional analysis of the Saccharomyces cerevisiae nicotinamidase gene, PNC1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Analysis of Sir2p domains required for rDNA and telomeric silencing in Saccharomyces cerevisiae.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Distribution of a limited Sir2 protein pool regulates the strength of yeast rDNA silencing and is modulated by Sir4p

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Extrachromosomal rDNA circles--a cause of aging in yeast

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

An unusual form of transcriptional silencing in yeast ribosomal DNA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

A useful colony colour phenotype associated with the yeast selectable/counter-selectable marker MET15.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

The effect of retarded growth upon the length of life span and upon the ultimate body size. 1935

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Lifespan extension in Caenorhabditis elegans by complete removal of food.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

SIR2 regulates recombination between different rDNA repeats, but not recombination within individual rRNA genes in yeast.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Evidence that Set1, a factor required for methylation of histone H3, regulates rDNA silencing in S. cerevisiae by a Sir2-independent mechanism

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163344

Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast

26 November 2018

1 reference

12 December 2020

Increase in activity during calorie restriction requires Sirt1

1 reference

12 December 2020

Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction"

1 reference

12 December 2020

Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage

1 reference

12 December 2020

Linker histone H1 represses recombination at the ribosomal DNA locus in the budding yeast Saccharomyces cerevisiae

1 reference

12 December 2020

An intervention resembling caloric restriction prolongs life span and retards aging in yeast

1 reference

12 December 2020

Role of NAD(+) in the deacetylase activity of the SIR2-like proteins

1 reference

12 December 2020

Distinct roles of processes modulated by histone deacetylases Rpd3p, Hda1p, and Sir2p in life extension by caloric restriction in yeast

1 reference

12 December 2020

10.1111/J.1474-9726.2009.00516.X

Identifiers

DOI

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1 September 2017

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1 September 2017

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