Evidence for activation of inflammatory lipoxygenase pathways in visceral adipose tissue of obese Zucker rats (Q30429027)

16 October 2017

Evidence for activation of inflammatory lipoxygenase pathways in visceral adipose tissue of obese Zucker rats (English)

1 reference

regulation of gene expression

16 October 2017

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978234

10 August 2024

4

Banumathi K Cole

1 reference

16 October 2017

Yeshao Wen

2

1 reference

16 October 2017

Qian Ma

5

1 reference

16 October 2017

Hong Pei

6

1 reference

16 October 2017

Jiali Gu

11

1 reference

16 October 2017

Swarup K. Chakrabarti

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978234

10 August 2024

Anca D. Dobrian

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978234

10 August 2024

Michael D. Williams

7

1 reference

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10 August 2024

Melissa H. Bevard

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978234

10 August 2024

George E. Vandenhoff

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978234

10 August 2024

Susanna R. Keller

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978234

10 August 2024

Jerry L. Nadler

12

1 reference

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10 August 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20978234

10 August 2024

publication date

26 October 2010

1 reference

full work available at URL

16 October 2017

https://europepmc.org/articles/pmc3023204

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978234

http://intl-ajpendo.physiology.org/cgi/content/abstract/300/1/E175

10 August 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978234

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20978234/?tool=EBI

10 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978234

https://europepmc.org/articles/PMC3023204

10 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978234

https://doi.org/10.1152/ajpendo.00203.2010

10 August 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978234

https://www.physiology.org/doi/pdf/10.1152/ajpendo.00203.2010

10 August 2024

1 reference

10.1152/AJPENDO.00203.2010

DOI

https://api.crossref.org/works/10.1152/AJPENDO.00203.2010

American Journal of Physiology - Endocrinology and Metabolism

10 August 2024

published in

1 reference

16 October 2017

300

1 reference

16 October 2017

1

1 reference

16 October 2017

E175-87

1 reference

Saturated- and n-6 polyunsaturated-fat diets each induce ceramide accumulation in mouse skeletal muscle: reversal and improvement of glucose tolerance by lipid metabolism inhibitors

16 October 2017

1 reference

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12-Lipoxygenase Products Reduce Insulin Secretion and {beta}-Cell Viability in Human Islets

20 June 2018

1 reference

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Macrophage death and defective inflammation resolution in atherosclerosis

20 June 2018

1 reference

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Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice

20 June 2018

1 reference

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Antagonistic effects of thiazolidinediones and cytokines in lipotoxicity

20 June 2018

1 reference

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12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Inflammation and impaired adipogenesis in hypertrophic obesity in man.

20 June 2018

1 reference

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12/15-lipoxygenase products induce inflammation and impair insulin signaling in 3T3-L1 adipocytes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Macrophage-derived human resistin exacerbates adipose tissue inflammation and insulin resistance in mice.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy

20 June 2018

1 reference

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Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

5-Lipoxygenase-activating protein: a potential link between innate and adaptive immunity in atherosclerosis and adipose tissue inflammation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

The role of 12/15-lipoxygenase in the expression of interleukin-6 and tumor necrosis factor-alpha in macrophages

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Mechanisms linking obesity with cardiovascular disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Mechanisms linking obesity to insulin resistance and type 2 diabetes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Synthesis and biological evaluation of lisofylline (LSF) analogs as a potential treatment for Type 1 diabetes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

The 5 lipoxygenase system in the vasculature: emerging role in health and disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Elevated glucose and diabetes promote interleukin-12 cytokine gene expression in mouse macrophages

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Inflamed fat: what starts the fire?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Activation of the 12-lipoxygenase and signal transducer and activator of transcription pathway during neointima formation in a model of the metabolic syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Adipose tissue, inflammation, and cardiovascular disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Activation of 12-lipoxygenase in proinflammatory cytokine-mediated beta cell toxicity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

IKK-beta links inflammation to obesity-induced insulin resistance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Metabolic syndrome: a clinical and molecular perspective

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Lisofylline: a potential lead for the treatment of diabetes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Obesity, Metabolic Syndrome, and Cardiovascular Disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Lipid inflammatory mediators in diabetic vascular disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Autoimmune diabetes is blocked in Stat4-deficient mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Obesity, insulin resistance, and cardiovascular disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Obesity is associated with macrophage accumulation in adipose tissue

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Thiazolidinediones in type 2 diabetes mellitus: current clinical evidence

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: an adipokine-mediated process?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Inflammatory status and insulin resistance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

CAP defines a second signalling pathway required for insulin-stimulated glucose transport

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Plasma interleukin-6, tumour necrosis factor alpha and blood cytokine production in type 2 diabetes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

Obesity and insulin resistance

20 June 2018

1 reference

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Tumor necrosis factor alpha: a key component of the obesity-diabetes link

20 June 2018

1 reference

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Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023204

A simplification of the protein assay method of Lowry et al. which is more generally applicable

20 June 2018

1 reference

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The Zucker-fatty rat: a review

20 June 2018

1 reference

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Systemic inflammation, adipose tissue tumor necrosis factor, and leptin expression.

20 June 2018

1 reference

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Low-grade systemic inflammation and the development of type 2 diabetes: the atherosclerosis risk in communities study

21 January 2018

1 reference

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5-lipoxygenase activating protein signals adipose tissue inflammation and lipid dysfunction in experimental obesity.

21 January 2018

1 reference

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Leukotriene B4 strongly increases monocyte chemoattractant protein-1 in human monocytes

21 January 2018

1 reference

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ALOX5AP expression, but not gene haplotypes, is associated with obesity and insulin resistance

21 January 2018

1 reference

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12-lipoxygenase is increased in glucose-stimulated mesangial cells and in experimental diabetic nephropathy

21 January 2018

1 reference

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Interleukin-6 stimulates hepatic triglyceride secretion in rats

21 January 2018

1 reference

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IKKepsilon: a bridge between obesity and inflammation

21 January 2018

1 reference

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Is type II diabetes mellitus a disease of the innate immune system?

21 January 2018

1 reference

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5-lipoxygenase-derived leukotrienes: mediators also of atherosclerotic inflammation

21 January 2018

1 reference

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Relationship between adipocyte size and adipokine expression and secretion

21 January 2018

1 reference

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Obesity, insulin resistance, diabetes, and cardiovascular risk in children: an American Heart Association scientific statement from the Atherosclerosis, Hypertension, and Obesity in the Young Committee (Council on Cardiovascular Disease in the Young

21 January 2018

1 reference

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Aldosterone increases osteopontin gene expression in rat endothelial cells

21 January 2018

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IL-12 serum levels in patients with type 2 diabetes treated with sulphonylureas

21 January 2018

1 reference

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Obesity and the metabolic syndrome in children and adolescents

21 January 2018

1 reference

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T-ing up inflammation in fat

21 January 2018

1 reference

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Adipose tissue IL-6 content correlates with resistance to insulin activation of glucose uptake both in vivo and in vitro

21 January 2018

1 reference

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Selective pharmacologic inhibition of murine and human IL-12-dependent Th1 differentiation and IL-12 signaling.

26 November 2018

1 reference

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Interleukin-1 beta regulates the expression of a leukocyte type of 12-lipoxygenase in rat islets and RIN m5F cells

26 November 2018

1 reference

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Primary cultures of rat cerebellar granule cells as a model to study neuronal 5-lipoxygenase and FLAP gene expression

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20978234

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Interleukin 12 and autoimmune diabetes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20978234

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Federation Proceedings

9

36

148

Bray GA

1977

1 reference

10.1152/AJPENDO.00203.2010

DOI

https://api.crossref.org/works/10.1152/AJPENDO.00203.2010

10.1152/AJPENDO.00203.2010

10 August 2024

Identifiers

DOI

1 reference

16 October 2017

1 reference

16 October 2017

1 reference