In vitro scanning saturation mutagenesis of an antibody binding pocket (Q30426325)

11 August 2017

In vitro scanning saturation mutagenesis of an antibody binding pocket (English)

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11 August 2017

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Burks EA

1

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11 August 2017

Chen G

series ordinal

2

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11 August 2017

Georgiou G

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3

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11 August 2017

Iverson BL

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4

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11 August 2017

language of work or name

English

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publication date

1 January 1997

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11 August 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

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published in

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11 August 2017

94

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11 August 2017

412-417

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11 August 2017

2

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Immunization with phage-displayed mimotopes.

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

A rapid screen of active site mutants in glycinamide ribonucleotide transformylase.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Minimizing a binding domain from protein A.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Saturation mutagenesis of the WSXWS motif of the erythropoietin receptor.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Binding in the growth hormone receptor complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Production and fluorescence-activated cell sorting of Escherichia coli expressing a functional antibody fragment on the external surface

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Activation and release of enzymatically inactive, full-length rhodanese that is bound to ribosomes as peptidyl-tRNA.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Contribution of a single heavy chain residue to specificity of an anti-digoxin monoclonal antibody

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

In vitro antibody maturation. Improvement of a high affinity, neutralizing antibody against IL-1 beta.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Human antibodies from combinatorial libraries.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Structural features of the reactions between antibodies and protein antigens.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Enhancement and destruction of antibody function by somatic mutation: unequal occurrence is controlled by V gene combinatorial associations.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Rapid, high-yield recovery of a recombinant digoxin binding single chain Fv from Escherichia coli

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Affinity maturation of the BR96 anti-carcinoma antibody by codon-based mutagenesis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Contribution of antibody heavy chain CDR1 to digoxin binding analyzed by random mutagenesis of phage-displayed Fab 26-10.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Receptor and antibody epitopes in human growth hormone identified by homolog-scanning mutagenesis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Probing the combining site of an anti-carbohydrate antibody by saturation-mutagenesis: role of the heavy-chain CDR3 residues.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Heavy chain position 50 is a determinant of affinity and specificity for the anti-digoxin antibody 26-10.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19525

Characterization of antibodies of high affinity and specificity for the digitalis glycoside digoxin

26 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.94.2.412

Analysis of amino acid indices and mutation matrices for sequence comparison and structure prediction of proteins

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.94.2.412

Characterization of an anti-digoxin antibody binding site by site-directed in vitro mutagenesis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.94.2.412

Electrochemiluminescence detection for development of immunoassays and DNA probe assays for clinical diagnostics

21 January 2018

1 reference

12 December 2020

High-affinity monoclonal antibodies to the cardiac glycoside, digoxin

1 reference

12 December 2020

Modulation of antibody affinity by an engineered amino acid substitution

1 reference

12 December 2020

Effects of substitutions of closely related amino acids at the contact surface in an antigen-antibody complex on thermodynamic parameters

1 reference

12 December 2020

Tolerance of single, but not multiple, amino acid replacements in antibody VH CDR 2: a means of minimizing B cell wastage from somatic hypermutation?

1 reference

12 December 2020

Screening of phage antibody libraries

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.94.2.412

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11 August 2017

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11 August 2017

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