Organs-on-chips: breaking the in vitro impasse (Q30413796)

21 June 2017

Organs-on-chips: breaking the in vitro impasse (English)

1 reference

21 June 2017

2

Albert van den Berg

1 reference

21 June 2017

Andries D van der Meer

series ordinal

1

1 reference

21 June 2017

5 March 2012

1 reference

21 June 2017

1 reference

21 June 2017

4

1 reference

21 June 2017

461-470

1 reference

21 June 2017

5

1 reference

Use of multiple assay endpoints to investigate the effects of incubation time, dose of toxin, and plating density in cell-based cytotoxicity assays

21 June 2017

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Simplifying complexity: a review of complexity theory

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Microfabrication and microfluidics for tissue engineering: state of the art and future opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Microscale technologies for tissue engineering and biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Engineering tumors with 3D scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Engineered microenvironments for controlled stem cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Matrix elasticity directs stem cell lineage specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Emergence of patterned stem cell differentiation within multicellular structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Designing materials to direct stem-cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

The tumor microenvironment and its role in promoting tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Capturing complex 3D tissue physiology in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Can cancer be reversed by engineering the tumor microenvironment?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Tensional homeostasis and the malignant phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

From 3D cell culture to organs-on-chips

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Reconstituting organ-level lung functions on a chip

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Computer-controlled microcirculatory support system for endothelial cell culture and shearing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Microfluidic cardiac cell culture model (μCCCM).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

BioMEMS: state-of-the-art in detection, opportunities and prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

The origins and the future of microfluidics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Biomimetics: lessons from nature--an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Mechanical control of tissue and organ development

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Mechanical control of tissue growth: function follows form

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Cell culture models of the respiratory tract relevant to pulmonary drug delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Epithelium damage and protection during reopening of occluded airways in a physiologic microfluidic pulmonary airway model

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Combination of fluid and solid mechanical stresses contribute to cell death and detachment in a microfluidic alveolar model

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Endothelial injury in the initiation and progression of vascular disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Images in cardiovascular medicine. Avoiding papillary muscle infarction with myocardial contrast echocardiographic guidance of nonsurgical septal reduction therapy for hypertrophic obstructive cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Adhesion mechanisms in platelet function

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Molecular basis of the effects of shear stress on vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Microfluidic technology in vascular research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Endothelialized networks with a vascular geometry in microfabricated poly(dimethyl siloxane).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Analyzing shear stress-induced alignment of actin filaments in endothelial cells with a microfluidic assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

A microfluidic membrane device to mimic critical components of the vascular microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Idiosyncratic drug hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Trends in the development of microfluidic cell biochips for in vitro hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Microfluidic devices for in vitro studies on liver drug metabolism and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Microscale culture of human liver cells for drug development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Perfused multiwell plate for 3D liver tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Rapid heterogeneous liver-cell on-chip patterning via the enhanced field-induced dielectrophoresis trap

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Microfluidic environment for high density hepatocyte culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

A microfluidic bioreactor with integrated transepithelial electrical resistance (TEER) measurement electrodes for evaluation of renal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Engineered approaches to the stem cell microenvironment for cardiac tissue regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Microscale 3-D hydrogel scaffold for biomimetic gastrointestinal (GI) tract model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Application of microfluidic technology to pancreatic islet research: first decade of endeavor

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Microfluidics: a new cosset for neurobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Towards a human-on-chip: culturing multiple cell types on a chip with compartmentalized microenvironments

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Incorporation of 3T3-L1 cells to mimic bioaccumulation in a microscale cell culture analog device for toxicity studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

A microfluidic device for a pharmacokinetic-pharmacodynamic (PK-PD) model on a chip

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Metabolic control through hepatocyte and adipose tissue cross-talk in a multicompartmental modular bioreactor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Micro total bioassay system for ingested substances: assessment of intestinal absorption, hepatic metabolism, and bioactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Characterization of drug metabolites and cytotoxicity assay simultaneously using an integrated microfluidic device

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

A microfluidic approach for in vitro assessment of interorgan interactions in drug metabolism using intestinal and liver slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Miniaturized total chemical analysis systems: A novel concept for chemical sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Electrochemistry-on-chip for on-line conversions in drug metabolism studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Role of smooth muscle cells in the initiation and early progression of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Vascular smooth muscle phenotypic diversity and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Multi-channel peristaltic pump for microfluidic applications featuring monolithic PDMS inlay

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Computerized microfluidic cell culture using elastomeric channels and Braille displays

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Passive microfluidic pumping using coupled capillary/evaporation effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Flow rate analysis of a surface tension driven passive micropump.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

A passive pumping method for microfluidic devices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Gravity-induced convective flow in microfluidic systems: electrochemical characterization and application to enzyme-linked immunosorbent assay tests.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Rapid prototyping of arrayed microfluidic systems in polystyrene for cell-based assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Microfluidics and photonics for Bio-System-on-a-Chip: a review of advancements in technology towards a microfluidic flow cytometry chip

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

PCR microfluidic devices for DNA amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Microfluidic polyacrylamide gel electrophoresis with in situ immunoblotting for native protein analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Differentiation of human oligodendrocytes from pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Generation of complex, static solution gradients in microfluidic channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Biological applications of microfluidic gradient devices

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Engineering challenges of BioNEMS: the integration of microfluidics, micro- and nanodevices, models and external control for systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Microfluidic chemostat and turbidostat with flow rate, oxygen, and temperature control for dynamic continuous culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Quantitative measurement and control of oxygen levels in microfluidic poly(dimethylsiloxane) bioreactors during cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Microfluidics meet cell biology: bridging the gap by validation and application of microscale techniques for cell biological assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Automated cell culture in high density tubeless microfluidic device arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

A microfluidic chip for electrochemical conversions in drug metabolism studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

Subcellular positioning of small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00176D

21 January 2018

Identifiers

DOI

10.1039/C2IB00176D

1 reference

21 June 2017

1 reference

PubMed ID

22388577