Complement is activated by IgG hexamers assembled at the cell surface (Q30409381)

12 November 2017

Complement is activated by IgG hexamers assembled at the cell surface (English)

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12 November 2017

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12 November 2017

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12 November 2017

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12 November 2017

Christoph A Diebolder

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Ian Andrew Wilson

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object named as

Ian A Wilson

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12 November 2017

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Dennis R Burton

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12 November 2017

Frank J Beurskens

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12 November 2017

Kristin Strumane

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12 November 2017

Margaret A Lindorfer

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12 November 2017

Marleen Voorhorst

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12 November 2017

Deniz Ugurlar

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12 November 2017

Sara Rosati

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12 November 2017

Jan G J van de Winkel

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12 November 2017

Ronald P Taylor

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12 November 2017

Janine Schuurman

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12 November 2017

Piet Gros

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12 November 2017

language of work or name

English

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publication date

1 March 2014

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12 November 2017

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12 November 2017

343

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12 November 2017

6176

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12 November 2017

1260-1263

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Immunoglobulin flexibility in complement activation.

12 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Structural Basis for Enhanced HIV-1 Neutralization by a Dimeric Immunoglobulin G Form of the Glycan-Recognizing Antibody 2G12

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Complement: a key system for immune surveillance and homeostasis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Complement and its role in innate and adaptive immune responses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

The human IgM pentamer is a mushroom-shaped molecule with a flexural bias

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): considerably higher levels of CDC are induced by OFA than by RTX.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

The biological activity of human CD20 monoclonal antibodies is linked to unique epitopes on CD20.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Structure and activation of the C1 complex of complement: unraveling the puzzle.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

C1q: structure, function, and receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Convergent solutions to binding at a protein-protein interface

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Complement Fixation on Cell Surfaces by 19 S and 7 S Antibodies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Quantitative immunology of immune hemolytic anemia. I. The fixation of C1 by autoimmune antibody and heterologous anti-IgG antibody

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Cooperative binding of a complement component to antigen-antibody complexes. II. Effect of variations in temperature and ionic strength

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Immunoglobulin G: functional sites

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Antibody: the flexible adaptor molecule

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Reaction between the isolated globular sub-units of the complement component Clq and IgG-complexes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250092

Importance of antigen specificity for complement-mediated lysis by monoclonal antibodies.

20 June 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Crystallization and preliminary structure determination of an intact human immunoglobulin, b12: an antibody that broadly neutralizes primary isolates of HIV-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Complement-Dependent Tumor Cell Lysis Triggered by Combinations of Epidermal Growth Factor Receptor Antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Effect of Target Dynamics on Pharmacokinetics of a Novel Therapeutic Antibody against the Epidermal Growth Factor Receptor: Implications for the Mechanisms of Action

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Crosstalk between human IgG isotypes and murine effector cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Quantitative Analysis of the Interaction Strength and Dynamics of Human IgG4 Half Molecules by Native Mass Spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Computer visualization of three-dimensional image data using IMOD

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Dual-axis tomography: an approach with alignment methods that preserve resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

The molecular architecture of axonemes revealed by cryoelectron tomography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

CTF determination and correction in electron cryotomography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Clustering and variance maps for cryo-electron tomography using wedge-masked differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

VADAR: a web server for quantitative evaluation of protein structure quality

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Hydration structure of a collagen peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

X-ray structure of the Ca2+-binding interaction domain of C1s. Insights into the assembly of the C1 complex of complement

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Crystal structure of the CUB1-EGF-CUB2 domain of human MASP-1/3 and identification of its interaction sites with mannan-binding lectin and ficolins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Structural basis of mannan-binding lectin recognition by its associated serine protease MASP-1: implications for complement activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Using Sculptor and Situs for simultaneous assembly of atomic components into low-resolution shapes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Using Situs for the integration of multi-resolution structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

UCSF Chimera--a visualization system for exploratory research and analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Atomic resolution model of the antibody Fc interaction with the complement C1q component

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Circular-dichroism and electron-microscopy studies of human subcomponent C1q before and after limited proteolysis by pepsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Molecular modelling of human complement subcomponent C1q and its complex with C1r2C1s2 derived from neutron-scattering curves and hydrodynamic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Identification of the C1q-binding Sites of Human C1r and C1s: a refined three-dimensional model of the C1 complex of complement

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Analogous interactions in initiating complexes of the classical and lectin pathways of complement

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Crystal structure of the catalytic domain of human complement c1s: a serine protease with a handle

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

The effect of the source pressure on the abundance of ions of noncovalent protein assemblies in an electrospray ionization orthogonal time-of-flight instrument

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Improving the Performance of a Quadrupole Time-of-Flight Instrument for Macromolecular Mass Spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1248943

Antibody density on rat red cells determines the rate of activation of the complement component C1

21 January 2018

1 reference

12 December 2020

Activation of complement pathways by univalent antibody derivatives with intact Fc zones

1 reference

12 December 2020

Is IgM-like dislocation a common feature of antibody function?

1 reference

12 December 2020

Human leukocyte antigen antibodies and human complement activation: role of IgG subclass, specificity, and cytotoxic potential

1 reference

12 December 2020

Measurement of antibody-dependent binding, proteolysis, and turnover of C1s on liposomal antigens localizes the fluidity-dependent step in C1 activation

1 reference

12 December 2020

Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen

1 reference

12 December 2020

Structural characteristics of hemolytic antibodies as determined by the effects of ionizing radiation

1 reference

12 December 2020

Identifiers

DOI

10.1126/SCIENCE.1248943

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12 November 2017

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12 November 2017

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