Ipilimumab plus sargramostim vs ipilimumab alone for treatment of metastatic melanoma: a randomized clinical trial (Q30407940)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25369488%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Ipilimumab plus sargramostim vs ipilimumab alone for treatment of metastatic melanoma: a randomized clinical trial (English)

1 reference

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22 February 2020

0 references

0 references

1 reference

5

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22 February 2020

Igor Puzanov

8

1 reference

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22 February 2020

1

F Stephen Hodi

1 reference

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22 February 2020

author name string

Sandra Lee

2

1 reference

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22 February 2020

David F McDermott

3

1 reference

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22 February 2020

Uma N Rao

4

1 reference

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22 February 2020

Ahmad A Tarhini

6

1 reference

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22 February 2020

Philip Leming

7

1 reference

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22 February 2020

Donghoon Shin

9

1 reference

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22 February 2020

John M Kirkwood

10

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22 February 2020

language of work or name

English

0 references

publication date

1 November 2014

1 reference

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The Journal of the American Medical Association

22 February 2020

published in

1 reference

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22 February 2020

volume

312

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22 February 2020

page(s)

1744-1753

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22 February 2020

issue

17

1 reference

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Increased frequency of ICOS+ CD4 T cells as a pharmacodynamic biomarker for anti-CTLA-4 therapy

22 February 2020

cites work

1 reference

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Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway tolerance

20 June 2018

1 reference

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Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

20 June 2018

1 reference

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Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial.

20 June 2018

1 reference

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The ICOS/ICOSL pathway is required for optimal antitumor responses mediated by anti-CTLA-4 therapy

20 June 2018

1 reference

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Ipilimumab plus dacarbazine for previously untreated metastatic melanoma

20 June 2018

1 reference

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Defective leukocyte GM-CSF receptor (CD116) expression and function in inflammatory bowel disease

20 June 2018

1 reference

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GM-CSF: a role in immune and inflammatory reactions in the intestine

20 June 2018

1 reference

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Sipuleucel-T immunotherapy for castration-resistant prostate cancer

20 June 2018

1 reference

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Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

20 June 2018

1 reference

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Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria

20 June 2018

1 reference

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Effect of granulocyte/macrophage colony-stimulating factor on circulating CD8+ and CD4+ T-cell responses to a multipeptide melanoma vaccine: outcome of a multicenter randomized trial

20 June 2018

1 reference

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The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease

20 June 2018

1 reference

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Potentiating endogenous antitumor immunity to prostate cancer through combination immunotherapy with CTLA4 blockade and GM-CSF.

20 June 2018

1 reference

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Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients

20 June 2018

1 reference

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Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4336189

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4336189

MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4336189

Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients

20 June 2018

1 reference

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CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells

20 June 2018

1 reference

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Immunomodulatory effects of human recombinant granulocyte-macrophage colony-stimulating factor (rhuGM-CSF): evidence of antitumour activity

20 June 2018

1 reference

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Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients

20 June 2018

1 reference

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Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accomp

20 June 2018

1 reference

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Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis

20 June 2018

1 reference

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Role of tumor-derived cytokines on the immune system of mice bearing a mammary adenocarcinoma. II. Down-regulation of macrophage-mediated cytotoxicity by tumor-derived granulocyte-macrophage colony-stimulating factor.

20 June 2018

1 reference

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Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

20 June 2018

1 reference

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A Multiple Testing Procedure for Clinical Trials

20 June 2018

1 reference

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Anti-CTLA-4 antibodies of IgG2a isotype enhance antitumor activity through reduction of intratumoral regulatory T cells

20 June 2018

1 reference

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Granulocyte-macrophage colony-stimulating factor autoantibodies in murine ileitis and progressive ileal Crohn's disease.

26 November 2018

1 reference

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Identification of GM-CSF in Paneth cells using single-cell RT-PCR.

26 November 2018

1 reference

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Therapy of advanced prostate cancer with granulocyte macrophage colony-stimulating factor.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4336189

Granulocyte-macrophage colony-stimulating factor activates macrophages derived from bone marrow cultures to synthesis of MHC class II molecules and to augmented antigen presentation function

26 November 2018

1 reference

12 December 2020

Granulocyte-macrophage colony stimulating factor and inflammatory bowel disease: establishing a connection

1 reference

12 December 2020

Identification of a New Subset of Myeloid Suppressor Cells in Peripheral Blood of Melanoma Patients With Modulation by a Granulocyte-Macrophage Colony-Stimulation Factor–Based Antitumor Vaccine

1 reference

12 December 2020

The role of granulocyte macrophage-colony-stimulating factor in acute intestinal inflammation

1 reference

12 December 2020

Human granulocyte-macrophage colony-stimulating factor is a neutrophil activator

1 reference

12 December 2020

Identifiers

DOI

10.1001/JAMA.2014.13943

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25369488%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25369488%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25369488%20AND%20SRC:MED&resulttype=core&format=json