The size of blood-brain barrier opening induced by focused ultrasound is dictated by the acoustic pressure (Q30407897)

5 November 2017

The size of blood-brain barrier opening induced by focused ultrasound is dictated by the acoustic pressure (English)

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5 November 2017

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2

Elisa E Konofagou

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5 November 2017

Hong Chen

1

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5 November 2017

30 April 2014

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Journal of Cerebral Blood Flow & Metabolism

5 November 2017

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5 November 2017

34

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5 November 2017

7

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5 November 2017

1197-1204

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PMCID

4083385

describes a project that uses

5 November 2017

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Targeted drug delivery with focused ultrasound-induced blood-brain barrier opening using acoustically-activated nanodroplets.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Noninvasive and targeted gene delivery into the brain using microbubble-facilitated focused ultrasound

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Focal Delivery of AAV2/1-transgenes Into the Rat Brain by Localized Ultrasound-induced BBB Opening.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Noninvasive and targeted drug delivery to the brain using focused ultrasound

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Improved anti-tumor effect of liposomal doxorubicin after targeted blood-brain barrier disruption by MRI-guided focused ultrasound in rat glioma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Dynamic study of blood-brain barrier closure after its disruption using ultrasound: a quantitative analysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Temporary disruption of the blood-brain barrier by use of ultrasound and microbubbles: safety and efficacy evaluation in rhesus macaques

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Activation of signaling pathways following localized delivery of systemically administered neurotrophic factors across the blood-brain barrier using focused ultrasound and microbubbles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Blood-brain barrier: real-time feedback-controlled focused ultrasound disruption by using an acoustic emissions-based controller

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Ultrasound-induced blood-brain barrier opening

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

The mechanism of interaction between focused ultrasound and microbubbles in blood-brain barrier opening in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Targeted drug delivery across the blood-brain barrier using ultrasound technique

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Feasibility of noninvasive cavitation-guided blood-brain barrier opening using focused ultrasound and microbubbles in nonhuman primates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Focused ultrasound-mediated bbb disruption is associated with an increase in activation of AKT: experimental study in rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

In vivo transcranial cavitation threshold detection during ultrasound-induced blood-brain barrier opening in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Multi-modality safety assessment of blood-brain barrier opening using focused ultrasound and definity microbubbles: a short-term study.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Antibodies targeted to the brain with image-guided focused ultrasound reduces amyloid-beta plaque load in the TgCRND8 mouse model of Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Reorganization of gap junctions after focused ultrasound blood-brain barrier opening in the rat brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Molecules of various pharmacologically-relevant sizes can cross the ultrasound-induced blood-brain barrier opening in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Microbubble-size dependence of focused ultrasound-induced blood-brain barrier opening in mice in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Ultrasound enhanced delivery of molecular imaging and therapeutic agents in Alzheimer's disease mouse models

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Permeability of blood-brain barrier to various sized molecules.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Size selectivity of blood-brain barrier permeability at various times after osmotic opening

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083385

Targeted gene delivery to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption.

20 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.71

Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.71

Vibrating microbubbles poking individual cells: drug transfer into cells via sonoporation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.71

Blood vessel deformations on microsecond time scales by ultrasonic cavitation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.71

Targeted disruption of the blood-brain barrier with focused ultrasound: association with cavitation activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.71

MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.71

Noninvasive, transcranial and localized opening of the blood-brain barrier using focused ultrasound in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.71

Drug delivery through the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.71

Drug transport across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.71

21 January 2018

Identifiers

DOI

10.1038/JCBFM.2014.71

1 reference

5 November 2017

1 reference

5 November 2017

1 reference

PMCID

4083385