Probing Small-Molecule Binding to the Liver-X Receptor: A Mixed-Model QSAR Study (Q30391044)

21 June 2017

Probing Small-Molecule Binding to the Liver-X Receptor: A Mixed-Model QSAR Study (English)

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21 June 2017

4

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author name string

Morena Spreafico

1

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21 June 2017

Martin Smiesko

2

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21 June 2017

Ourania Peristera

3

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21 June 2017

Angelo Vedani

5

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21 June 2017

1 January 2010

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21 June 2017

Molecular Informatics

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21 June 2017

29

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21 June 2017

1-2

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21 June 2017

27-36

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Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

21 June 2017

1 reference

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The three-dimensional structure of the liver X receptor beta reveals a flexible ligand-binding pocket that can accommodate fundamentally different ligands

8 April 2023

1 reference

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Macromodel?an integrated software system for modeling organic and bioorganic molecules using molecular mechanics

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Cholestenoic Acid Is a Naturally Occurring Ligand for Liver X Receptor α

8 April 2023

1 reference

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VirtualToxLab - in silico prediction of the toxic potential of drugs and environmental chemicals: evaluation status and internet access protocol.

8 April 2023

1 reference

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X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by a histidine-tryptophan switch

8 April 2023

1 reference

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A new force field for molecular mechanical simulation of nucleic acids and proteins

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1 reference

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4-(3-aryloxyaryl)quinoline alcohols are liver X receptor agonists

8 April 2023

1 reference

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Prediction of protein-ligand interactions. Docking and scoring: successes and gaps

8 April 2023

1 reference

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Class IV charge models: A new semiempirical approach in quantum chemistry

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1 reference

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Design, synthesis, and structure-activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis

8 April 2023

1 reference

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The important role of residue F268 in ligand binding by LXRbeta

8 April 2023

1 reference

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Crystal structure of the heterodimeric complex of LXR and RXR ligand-binding domains in a fully agonistic conformation

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1 reference

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The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism

8 April 2023

1 reference

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Diterpenoid, steroid, and triterpenoid agonists of liver X receptors from diversified terrestrial plants and marine sources

8 April 2023

1 reference

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Further modification on phenyl acetic acid based quinolines as liver X receptor modulators.

8 April 2023

1 reference

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Combining protein modeling and 6D-QSAR. Simulating the binding of structurally diverse ligands to the estrogen receptor.

8 April 2023

1 reference

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Novel ligands for the chemokine receptor-3 (CCR3): a receptor-modeling study based on 5D-QSAR.

8 April 2023

1 reference

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Crystal structure of the human liver X receptor beta ligand-binding domain in complex with a synthetic agonist

8 April 2023

1 reference

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Multiple-conformation and protonation-state representation in 4D-QSAR: the neurokinin-1 receptor system.

8 April 2023

1 reference

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Thyroid toxicants: assessing reproductive health effects

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1 reference

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A natural product ligand of the oxysterol receptor, liver X receptor.

8 April 2023

1 reference

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Indazole-based liver X receptor (LXR) modulators with maintained atherosclerotic lesion reduction activity but diminished stimulation of hepatic triglyceride synthesis

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900064

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

8 April 2023

1 reference

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Raptor: combining dual-shell representation, induced-fit simulation, and hydrophobicity scoring in receptor modeling: application toward the simulation of structurally diverse ligand sets

8 April 2023

1 reference

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Simulating alpha/beta selectivity at the human thyroid hormone receptor: consensus scoring using multidimensional QSAR

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900064

Aryl-hydrocarbon receptor-dependent pathway and toxic effects of TCDD in humans: a population-based study in Seveso, Italy

8 April 2023

1 reference

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Xenoendocrine disrupters: laboratory studies on male reproductive effects

8 April 2023

1 reference

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5D-QSAR: the key for simulating induced fit?

8 April 2023

1 reference

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SAR studies: designing potent and selective LXR agonists

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900064

Two- and three-dimensional quantitative structure-activity relationships studies on a series of liver x receptor ligands.

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900064

Discovery of phenyl acetic acid substituted quinolines as novel liver X receptor agonists for the treatment of atherosclerosis

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900064

Liver X Receptor Signaling Pathways in Cardiovascular Disease

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900064

BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900064

The liver X receptor gene team: potential new players in atherosclerosis

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900064

Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900064

8 April 2023

Identifiers

DOI

10.1002/MINF.200900064

1 reference

21 June 2017

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