Structure of a TCR-Mimic Antibody with Target Predicts Pharmacogenetics. (Q30382749)

14 August 2017

Structure of a TCR-Mimic Antibody with Target Predicts Pharmacogenetics. (English)

1 reference

14 August 2017

4

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9 June 2020

Ho Leung Ng

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9 June 2020

author name string

Niloufar Ataie

1

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9 June 2020

Jingyi Xiang

2

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9 June 2020

Neal Cheng

3

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9 June 2020

Wenjie Lu

5

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9 June 2020

David A Scheinberg

6

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9 June 2020

Cheng Liu

7

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9 June 2020

language of work or name

English

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publication date

11 December 2015

1 reference

Journal of Molecular Biology

14 August 2017

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9 June 2020

volume

428

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9 June 2020

issue

1

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9 June 2020

page(s)

194-205

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Therapeutic bispecific T-cell engager antibody targeting the intracellular oncoprotein WT1.

9 June 2020

cites work

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FEM: feature-enhanced map.

14 July 2018

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YASARA View - molecular graphics for all devices - from smartphones to workstations

14 July 2018

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Deconstructing the Peptide-MHC Specificity of T Cell Recognition

14 July 2018

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Therapeutic efficacy of an Fc-enhanced TCR-like antibody to the intracellular WT1 oncoprotein

14 July 2018

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A TCR-mimic antibody to WT1 bypasses tyrosine kinase inhibitor resistance in human BCR-ABL+ leukemias

14 July 2018

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Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma.

14 July 2018

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Targeting the intracellular WT1 oncogene product with a therapeutic human antibody.

14 July 2018

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14 July 2018

The cation-π interaction

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Linking Crystallographic Model and Data Quality

14 July 2018

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Antibody therapy of cancer

14 July 2018

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T-cell-receptor-like antibodies - generation, function and applications

14 July 2018

1 reference

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TCR-like biomolecules target peptide/MHC Class I complexes on the surface of infected and cancerous cells

14 July 2018

1 reference

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Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics

14 July 2018

1 reference

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Allele frequency net: a database and online repository for immune gene frequencies in worldwide populations

14 July 2018

1 reference

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Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A0201: Implications for WT1-based cancer therapeutics

14 July 2018

1 reference

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Safety and immunotoxicity assessment of immunomodulatory monoclonal antibodies

14 July 2018

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

14 July 2018

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14 July 2018

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T Cell Receptor Cross-reactivity Directed by Antigen-Dependent Tuning of Peptide-MHC Molecular Flexibility

14 July 2018

1 reference

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Molecular replacement with MOLREP

14 July 2018

1 reference

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Potential energy curves for cation-pi interactions: off-axis configurations are also attractive

14 July 2018

1 reference

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The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research

14 July 2018

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Phasercrystallographic software

14 July 2018

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Rational development of high-affinity T-cell receptor-like antibodies

14 July 2018

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New paradigm for macromolecular crystallography experiments at SSRL: automated crystal screening and remote data collection

14 July 2018

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How a T Cell Receptor-like Antibody Recognizes Major Histocompatibility Complex-bound Peptide

14 July 2018

1 reference

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Thermodynamics of T-cell receptor-peptide/MHC interactions: progress and opportunities

14 July 2018

1 reference

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NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8-11

14 July 2018

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Inference of macromolecular assemblies from crystalline state

14 July 2018

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Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry

14 July 2018

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A tumor suppressor and oncogene: the WT1 story.

14 July 2018

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14 July 2018

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Refinement of macromolecular structures by the maximum-likelihood method

14 July 2018

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A point-charge force field for molecular mechanics simulations of proteins based on condensed-phase quantum mechanical calculations

14 July 2018

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CDR3 loop flexibility contributes to the degeneracy of TCR recognition

14 July 2018

1 reference

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Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells

14 July 2018

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TCR-like human antibodies expressed on human CTLs mediate antibody affinity-dependent cytolytic activity.

14 July 2018

1 reference

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HLA class I-restricted lysis of leukemia cells by a CD8(+) cytotoxic T-lymphocyte clone specific for WT1 peptide

14 July 2018

1 reference

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Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical

14 July 2018

1 reference

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Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids

14 July 2018

1 reference

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Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

14 July 2018

1 reference

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Amino-aromatic interactions in proteins

14 July 2018

1 reference

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Wilms' tumour gene 1 (WT1) in human neoplasia.

14 July 2018

1 reference

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A major histocompatibility complex-peptide-restricted antibody and t cell receptor molecules recognize their target by distinct binding modes: crystal structure of human leukocyte antigen (HLA)-A1-MAGE-A1 in complex with FAB-HYB3.

26 November 2018

1 reference

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TCR binding to peptide-MHC stabilizes a flexible recognition interface

26 November 2018

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12 December 2020

Human cytotoxic T-lymphocyte responses specific for peptides of the wild-type Wilms' tumor gene (WT1 ) product

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12 December 2020

Frequencies of HLA-A2 alleles in five U.S. population groups. Predominance Of A*02011 and identification of HLA-A*0231

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12 December 2020

Two different T cell receptors use different thermodynamic strategies to recognize the same peptide/MHC ligand

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12 December 2020

Cation-π, amino-π, π-π, and H-bond interactions stabilize antigen-antibody interfaces

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12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

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12 December 2020

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9 June 2020

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