Hormone and glucose signalling in POMC and AgRP neurons. (Q30380963)

21 June 2017

1 reference

title

Hormone and glucose signalling in POMC and AgRP neurons. (English)

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21 June 2017

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3

Jens C Brüning

1 reference

21 June 2017

Bengt F Belgardt

1

1 reference

PubMed ID

19770186

21 June 2017

Tomoo Okamura

series ordinal

2

1 reference

PubMed ID

19770186

21 June 2017

language of work or name

English

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publication date

21 September 2009

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21 June 2017

Journal of Physiology

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21 June 2017

587

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21 June 2017

Pt 22

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21 June 2017

5305-5314

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Regulation of KATP channel subunit gene expression by hyperglycemia in the mediobasal hypothalamus of female rats.

21 June 2017

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Evidence from glut2-null mice that glucose is a critical physiological regulator of feeding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Triglycerides induce leptin resistance at the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Identification of SOCS-3 as a potential mediator of central leptin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Role of brain insulin receptor in control of body weight and reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Leptin controls adipose tissue lipogenesis via central, STAT3-independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Glucose-sensing neurons of the hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Induction of leptin resistance through direct interaction of C-reactive protein with leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Effects of recombinant leptin therapy in a child with congenital leptin deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Weight-reducing effects of the plasma protein encoded by the obese gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Obese men respond to cognitive but not to catabolic brain insulin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Insulin receptors are widely distributed in the central nervous system of the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Ovarian steroids stimulate adenosine triphosphate-sensitive potassium (KATP) channel subunit gene expression and confer responsiveness of the gonadotropin-releasing hormone pulse generator to KATP channel modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Effects of leptin on rat ventromedial hypothalamic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Topographical distribution of pro-opiomelanocortin-derived peptides (ACTH/beta-END/alpha-MSH) in the rat median eminence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocyte-dependent glucose sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Developmental switch in neuropeptide Y and melanocortin effects in the paraventricular nucleus of the hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Activation of Stat3 signaling in AgRP neurons promotes locomotor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATP channel activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Hypothalamic responses to long-chain fatty acids are nutritionally regulated

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Region-specific leptin resistance within the hypothalamus of diet-induced obese mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Intracellular signalling. Key enzyme in leptin-induced anorexia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

RECIPROCAL ACTIVITIES OF THE VENTROMEDIAL AND LATERAL HYPOTHALAMIC AREAS OF CATS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Rapid rewiring of arcuate nucleus feeding circuits by leptin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Central insulin action in energy and glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Enhanced leptin-stimulated Pi3k activation in the CNS promotes white adipose tissue transdifferentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Different glibenclamide-sensitivity of ATP-sensitive K+ currents using different patch-clamp recording methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Orexigen-sensitive NPY/AgRP pacemaker neurons in the hypothalamic arcuate nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Recruitment of functional GABA(A) receptors to postsynaptic domains by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased pomc expression, mild obesity, and defects in compensatory refeeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Glucokinase regulates reproductive function, glucocorticoid secretion, food intake, and hypothalamic gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Actin cytoskeleton dynamics promotes leptin-induced vascular smooth muscle hypertrophy via RhoA/ROCK- and phosphatidylinositol 3-kinase/protein kinase B-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.179192

Central insulin action regulates peripheral glucose and fat metabolism in mice

21 January 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793863

PI3K integrates the action of insulin and leptin on hypothalamic neurons

26 November 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793863

Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19770186

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19770186

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1113/JPHYSIOL.2009.179192

1 reference

release_crgus5orrra6tmprolysfak7cy

21 June 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/crgus5orrra6tmprolysfak7cy

mapped directly with Wikidata item

24 November 2022

based on heuristic

0 references

1 reference

PubMed ID

19770186