Ii-Key/MHC class II epitope hybrids: a strategy that enhances MHC class II epitope loading to create more potent peptide vaccines. (Q30359230)

20 June 2017

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title

Ii-Key/MHC class II epitope hybrids: a strategy that enhances MHC class II epitope loading to create more potent peptide vaccines. (English)

1 reference

20 June 2017

Nikoletta L Kallinteris

1

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20 June 2017

Xueqing Lu

2

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20 June 2017

Catherine E Blackwell

3

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20 June 2017

Eric von Hofe

4

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20 June 2017

Robert E Humphreys

5

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20 June 2017

Minzhen Xu

6

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20 June 2017

language of work or name

English

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publication date

1 December 2006

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Expert Opinion on Biological Therapy

20 June 2017

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20 June 2017

6

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20 June 2017

12

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20 June 2017

1311-1321

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Enhancing antitumor immune responses: intracellular peptide delivery and identification of MHC class II-restricted tumor antigens

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Diversity of endogenous epitopes bound to MHC class II molecules limited by invariant chain

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Cathepsin B cleavage and release of invariant chain from MHC class II molecules follow a staged pattern

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More efficient peptide binding to MHC class II molecules during cathepsin B digestion of Ii than after Ii release

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Invariant chain dissociation from class II MHC is a catalyst for foreign peptide binding

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MHC class II-associated invariant chain contains a sorting signal for endosomal compartments

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Inhibition by leupeptin and antipain of the intracellular proteolysis of Ii.

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Role for cathepsin F in invariant chain processing and major histocompatibility complex class II peptide loading by macrophages

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Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading

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Trafficking of MHC class II molecules in the late secretory pathway

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HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides

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An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules

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HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilitates peptide loading

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Tumor antigen-specific T helper cells in cancer immunity and immunotherapy

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CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.

21 January 2018

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Activation of tumor-specific CD4(+) T lymphocytes by major histocompatibility complex class II tumor cell vaccines: a novel cell-based immunotherapy.

21 January 2018

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Specific T helper cell requirement for optimal induction of cytotoxic T lymphocytes against major histocompatibility complex class II negative tumors

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Multiple HLA class II-restricted melanocyte differentiation antigens are recognized by tumor-infiltrating lymphocytes from a patient with melanoma

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Complementary role of CD4+ T cells and secondary lymphoid tissues for cross-presentation of tumor antigen to CD8+ T cells.

21 January 2018

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CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.

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Identification of multiple HLA-DR-restricted epitopes of the tumor-associated antigen CAMEL by CD4+ Th1/Th2 lymphocytes

21 January 2018

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Acute hepatitis C without and with schistosomiasis: correlation with hepatitis C-specific CD4(+) T-cell and cytokine response.

21 January 2018

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21 January 2018

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21 January 2018

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A peptide binding weakly to the major histocompatibility molecule augments T cell responses

21 January 2018

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Selective release of some invariant chain-derived peptides from HLA-DR1 molecules at endosomal pH

21 January 2018

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Self-release of CLIP in peptide loading of HLA-DR molecules

21 January 2018

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21 January 2018

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Quantitative analysis of peptide-MHC class II interaction

21 January 2018

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ISCOM-based vaccines: the second decade.

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Bacterial heat shock proteins promote CD91-dependent class I MHC cross-presentation of chaperoned peptide to CD8+ T cells by cytosolic mechanisms in dendritic cells versus vacuolar mechanisms in macrophages.

21 January 2018

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The L.E.A.P.S. approach to vaccine development

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21 January 2018

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21 January 2018

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An accessory peptide binding site with allosteric effect on the formation of peptide-MHC-II complexes?

21 January 2018

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Functionally divergent T lymphocyte responses induced by modification of a self-peptide from a tumor-associated antigen

21 January 2018

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10.1517/14712598.6.12.1311

21 January 2018

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20 June 2017

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