SuperBiHelix method for predicting the pleiotropic ensemble of G-protein-coupled receptor conformations. (Q30356936)

20 August 2017

SuperBiHelix method for predicting the pleiotropic ensemble of G-protein-coupled receptor conformations. (English)

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G protein-coupled receptor

20 August 2017

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1 reference

Ravinder Abrol

2

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Bartosz Trzaskowski

object named as

Bartosz Trzaskowski

4

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author name string

Jenelle K Bray

1

1 reference

20 August 2017

William A Goddard

3

1 reference

20 August 2017

Caitlin E Scott

5

1 reference

20 August 2017

language of work or name

English

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publication date

16 December 2013

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Proceedings of the National Academy of Sciences of the United States of America

20 August 2017

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20 August 2017

111

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20 August 2017

E72-8

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20 August 2017

1

1 reference

Flat-Bottom Strategy for Improved Accuracy in Protein Side-Chain Placements

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Use of G-protein-coupled and -uncoupled CCR5 receptors by CCR5 inhibitor-resistant and -sensitive human immunodeficiency virus type 1 variants.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Computationally-predicted CB1 cannabinoid receptor mutants show distinct patterns of salt-bridges that correlate with their level of constitutive activity reflected in G protein coupling levels, thermal stability, and ligand binding

3 June 2018

1 reference

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Molecular basis for dramatic changes in cannabinoid CB1 G protein-coupled receptor activation upon single and double point mutations

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Structure of the agonist-bound neurotensin receptor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Critical analysis of the successes and failures of homology models of G protein-coupled receptors.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Identification and characterization of an activating F229V substitution in the V2 vasopressin receptor in an infant with NSIAD.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Characterizing and predicting the functional and conformational diversity of seven-transmembrane proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Bihelix: Towards de novo structure prediction of an ensemble of G-protein coupled receptor conformations

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Structure-based prediction of subtype selectivity of histamine H3 receptor selective antagonists in clinical trials

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Crystal structure of the β2 adrenergic receptor-Gs protein complex

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Predicted structures of agonist and antagonist bound complexes of adenosine A3 receptor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Structure of an agonist-bound human A2A adenosine receptor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Crystal structure of metarhodopsin II

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Predicted structures and dynamics for agonists and antagonists bound to serotonin 5-HT2B and 5-HT2C receptors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

G-protein-coupled receptor structures were not built in a day

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Structural diversity of G protein-coupled receptors and significance for drug discovery

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Latest development in drug discovery on G protein-coupled receptors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

OPM: orientations of proteins in membranes database

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Drug design strategies for targeting G-protein-coupled receptors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

Predicted 3D structures for adenosine receptors bound to ligands: comparison to the crystal structure

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1321233111

Genetically encoded photo-cross-linkers map the binding site of an allosteric drug on a G protein-coupled receptor.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1321233111

3D structure prediction of TAS2R38 bitter receptors bound to agonists phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP).

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1321233111

Structure prediction of G protein-coupled receptors and their ensemble of functionally important conformations.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890820

26 November 2018

Identifiers

DOI

10.1073/PNAS.1321233111

1 reference

release_svnpxjvkyrhqrkblgzyfkkygdq

20 August 2017

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1 reference

Fatcat

https://api.fatcat.wiki/v0/release/svnpxjvkyrhqrkblgzyfkkygdq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

20 August 2017

1 reference