AlkB mystery solved: oxidative demethylation of N1-methyladenine and N3-methylcytosine adducts by a direct reversal mechanism. (Q30332381)

18 June 2017

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title

AlkB mystery solved: oxidative demethylation of N1-methyladenine and N3-methylcytosine adducts by a direct reversal mechanism. (English)

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18 June 2017

Thomas J Begley

1

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PubMed ID

12517444

18 June 2017

Leona D Samson

series ordinal

2

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18 June 2017

1 January 2003

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18 June 2017

4

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Trends in Biochemical Sciences

inferred from page(s)

published in

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18 June 2017

28

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18 June 2017

2-5

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18 June 2017

1

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A new gene (alkB) of Escherichia coli that controls sensitivity to methyl methane sulfonate

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1 reference

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Molecular cloning and characterization of the alkB gene of Escherichia coli

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The Escherichia coli AlkB protein protects human cells against alkylation-induced toxicity

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Suppression of Escherichia coli alkB mutants by Saccharomyces cerevisiae genes

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Repair in Escherichia coli alkB mutants of abasic sites and 3-methyladenine residues in DNA.

1 reference

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The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases

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The 2-His-1-carboxylate facial triad--an emerging structural motif in mononuclear non-heme iron(II) enzymes

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Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes

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Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

1 reference

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7 January 2021

AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli

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The suicidal DNA repair methyltransferases of microbes

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A new pathway for DNA repair in Escherichia coli

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An adaptive response of E. coli to low levels of alkylating agent: Comparison with previously characterised DNA repair pathways

1 reference

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Regulation and expression of the adaptive response to alkylating agents

1 reference

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Transcriptional activation of the Escherichia coli adaptive response gene aidB is mediated by binding of methylated Ada protein. Evidence for a new consensus sequence for Ada-binding sites.

1 reference

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Adaptation to alkylation resistance involves the induction of a DNA glycosylase

1 reference

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Endogenous genotoxic agents and processes as a basis of spontaneous carcinogenesis

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7 January 2021

10.1016/S0968-0004(02)00010-5

Identifiers

DOI

1 reference

18 June 2017

1 reference

PubMed ID

12517444