Metabolic engineering with a morphine biosynthetic P450 in opium poppy surpasses breeding (Q30319911)

17 June 2017

Metabolic engineering with a morphine biosynthetic P450 in opium poppy surpasses breeding (English)

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17 June 2017

metabolic engineering

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Susanne Frick

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PubMed ID

17189709

17 June 2017

Robert Kramell

series ordinal

2

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PubMed ID

17189709

17 June 2017

Toni M Kutchan

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3

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17 June 2017

6 November 2006

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17 June 2017

Metabolic Engineering

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17 June 2017

9

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17 June 2017

2

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17 June 2017

169-176

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RNAi-mediated replacement of morphine with the nonnarcotic alkaloid reticuline in opium poppy

17 June 2017

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A tale of three cell types: alkaloid biosynthesis is localized to sieve elements in opium poppy

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A second pathway for the terminal steps in the biosynthesis of morphine

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A brief history of opiates, opioid peptides, and opioid receptors

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Interactions among enzymes of the Arabidopsis flavonoid biosynthetic pathway

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A method for isolation of intact, translationally active ribonucleic acid.

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Antisense-mediated down-regulation of putrescine N-methyltransferase activity in transgenic Nicotiana tabacum L. can lead to elevated levels of anatabine at the expense of nicotine

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Genetic transformation in commercial Tasmanian cultivars of opium poppy, Papaver somniferum, and movement of transgenicpollen in the field

7 January 2021

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Molecular cloning, expression, and induction of berberine bridge enzyme, an enzyme essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack

7 January 2021

1 reference

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Flavonoids and isoflavonoids - a gold mine for metabolic engineering.

7 January 2021

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ALKALOID BIOSYNTHESIS IN PLANTS: Biochemistry, Cell Biology, Molecular Regulation, and Metabolic Engineering Applications

7 January 2021

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Molecular characterization of berberine bridge enzyme genes from opium poppy

7 January 2021

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Transformation of opium poppy (Papaver somniferum L.) with antisense berberine bridge enzyme gene (anti-bbe) via somatic embryogenesis results in an altered ratio of alkaloids in latex but not in roots

7 January 2021

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Comparative qualitative and quantitative determination of alkaloids in narcotic and condiment Papaver somniferum cultivars

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Distribution of morphinan and benzo[c]phenanthridine alkaloid gene transcript accumulation in Papaver somninferum

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Metabolic engineering of plants for alkaloid production.

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Cassava plants with a depleted cyanogenic glucoside content in leaves and tubers. Distribution of cyanogenic glucosides, their site of synthesis and transport, and blockage of the biosynthesis by RNA interference technology

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Metabolon formation and metabolic channeling in the biosynthesis of plant natural products

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A role for intra- and intercellular translocation in natural product biosynthesis

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A DNA transformation-competent Arabidopsis genomic library in Agrobacterium.

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Enhanced triterpene and phytosterol biosynthesis in Panax ginseng overexpressing squalene synthase gene

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Metabolic engineering of essential oil yield and composition in mint by altering expression of deoxyxylulose phosphate reductoisomerase and menthofuran synthase

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Cosuppression of limonene-3-hydroxylase in peppermint promotes accumulation of limonene in the essential oil.

7 January 2021

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Producing decaffeinated coffee plants

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Application of RNAi to confirm theobromine as the major intermediate for caffeine biosynthesis in coffee plants with potential for construction of decaffeinated varieties

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A polyamine metabolon involving aminopropyl transferase complexes in Arabidopsis.

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Antisense RNA-mediated suppression of benzophenanthridine alkaloid biosynthesis in transgenic cell cultures of California poppy

7 January 2021

1 reference

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Modulation of berberine bridge enzyme levels in transgenic root cultures of California poppy alters the accumulation of benzophenanthridine alkaloids

7 January 2021

1 reference

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Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3'-hydroxylase (CYP80B1), a new methyl jasmonate-inducible cytochrome P-450-dependent mono-oxygenase of benzylisoquinoline alkaloid biosynthesis

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Overexpression of tropinone reductases alters alkaloid composition in Atropa belladonna root cultures

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Cloning and heterologous expression of NADPH-cytochrome P450 reductases from the Papaveraceae

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Molecular cloning and functional expression of codeinone reductase: the penultimate enzyme in morphine biosynthesis in the opium poppy Papaver somniferum.

7 January 2021

1 reference

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Engineering the plant cell factory for secondary metabolite production

7 January 2021

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The roles of latex and the vascular bundle in morphine biosynthesis in the opium poppy, Papaver somniferum

7 January 2021

1 reference

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Metabolic channeling in plants.

7 January 2021

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Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells

7 January 2021

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Engineering tropane biosynthetic pathway in Hyoscyamus niger hairy root cultures

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1 reference

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10.1016/J.YMBEN.2006.10.004

7 January 2021

Identifiers

DOI

1 reference

17 June 2017

1 reference

PubMed ID

17189709