Novel ubiquitin-derived high affinity binding proteins with tumor targeting properties (Q30317537)

21 August 2017

Novel ubiquitin-derived high affinity binding proteins with tumor targeting properties (English)

1 reference

21 August 2017

Susan Lorey

1

1 reference

21 August 2017

Erik Fiedler

2

1 reference

21 August 2017

Anja Kunert

3

1 reference

21 August 2017

Jörg Nerkamp

4

1 reference

21 August 2017

Christian Lange

5

1 reference

21 August 2017

Markus Fiedler

6

1 reference

21 August 2017

Eva Bosse-Doenecke

7

1 reference

21 August 2017

Maren Meysing

8

1 reference

21 August 2017

Manja Gloser

9

1 reference

21 August 2017

Chris Rundfeldt

10

1 reference

21 August 2017

Una Rauchhaus

11

1 reference

21 August 2017

Ilka Hänssgen

12

1 reference

21 August 2017

Thomas Göttler

13

1 reference

21 August 2017

Arnd Steuernagel

14

1 reference

21 August 2017

Ulrike Fiedler

15

1 reference

21 August 2017

Ulrich Haupts

16

1 reference

21 August 2017

language of work or name

English

0 references

publication date

28 January 2014

1 reference

Journal of Biological Chemistry

21 August 2017

15

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

21 August 2017

289

1 reference

21 August 2017

12

1 reference

21 August 2017

8493-8507

1 reference

The emerging role of new protein scaffold-based agents for treatment of cancer

21 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Production and binding analyses of a humanised scFv against a cryptic epitope on tumour-associated fibronectin.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Combinatorial design of an Anticalin directed against the extra-domain b for the specific targeting of oncofetal fibronectin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Rebinding: or why drugs may act longer in vivo than expected from their in vitro target residence time

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Mechanisms of glomerular albumin filtration and tubular reabsorption

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Initial assessment of the role of CXC chemokine receptor 4 after polytrauma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Effects of exogenous ubiquitin in a polytrauma model with blunt chest trauma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

New binding mode to TNF-alpha revealed by ubiquitin-based artificial binding protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Neonatal Fc receptor and IgG-based therapeutics

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Structural determinants of ubiquitin-CXC chemokine receptor 4 interaction

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Strategies for extended serum half-life of protein therapeutics

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

The CXC chemokine receptor 4 ligands ubiquitin and stromal cell-derived factor-1α function through distinct receptor interactions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

DARPins and other repeat protein scaffolds: advances in engineering and applications

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Investigation of the pharmacokinetics of romiplostim in rodents with a focus on the clearance mechanism

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Ubiquitin receptor binding and signaling in primary human leukocytes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Radiolabeled affibody-albumin bioconjugates for HER2-positive cancer targeting

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Phase I and pharmacokinetic study of CT-322 (BMS-844203), a targeted Adnectin inhibitor of VEGFR-2 based on a domain of human fibronectin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Extracellular ubiquitin: immune modulator and endogenous opponent of damage-associated molecular pattern molecules

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Delivering cytokines at tumor site: The immunocytokine-conjugated anti-EDB-fibronectin antibody case.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Engineered protein scaffolds as next-generation antibody therapeutics.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Therapeutic antibodies: successes, limitations and hopes for the future

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Principles of ubiquitin and SUMO modifications in DNA repair.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

The ubiquitylation machinery of the endoplasmic reticulum

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Affilin-novel binding molecules based on human gamma-B-crystallin, an all beta-sheet protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

ElaD, a Deubiquitinating protease expressed by E. coli

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Ribosome display: selecting and evolving proteins in vitro that specifically bind to a target

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Crystal structure and solution NMR studies of Lys48-linked tetraubiquitin at neutral pH

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

A novel, non-immunogenic Fyn SH3-derived binding protein with tumor vascular targeting properties

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Ubiquitin: a small protein folding paradigm.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

PEGylation, successful approach to drug delivery

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Protein PEGylation decreases observed target association rates via a dual blocking mechanism

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Artificial, non-antibody binding proteins for pharmaceutical and industrial applications

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

ED-B fibronectin as a target for antibody-based cancer treatments

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

A twin-arginine translocation (Tat)-mediated phage display system

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Serum concentrations of free ubiquitin and multiubiquitin chains

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Enhanced binding and inertness to dehalogenation of alpha-melanotropic peptides labeled using N-succinimidyl 3-iodobenzoate

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Determination of the immunoreactive function of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Structure of ubiquitin refined at 1.8 A resolution

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Multiple sites of alternative splicing of the rat fibronectin gene transcript

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3961674

Marketed therapeutic antibodies compendium

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

Molecular imaging of HER2-expressing malignant tumors in breast cancer patients using synthetic 111In- or 68Ga-labeled affibody molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

Treatment of diabetic macular edema with a designed ankyrin repeat protein that binds vascular endothelial growth factor: a phase I/II study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

Therapeutic potential of exogenous ubiquitin during resuscitation from severe trauma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

Effects of exogenous ubiquitin in lethal endotoxemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

Selective targeting of tumour neovasculature by a radiohalogenated human antibody fragment specific for the ED-B domain of fibronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

Expression of the oncofetal ED-B-containing fibronectin isoform in hematologic tumors enables ED-B-targeted 131I-L19SIP radioimmunotherapy in Hodgkin lymphoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

The tumour-targeting human L19-IL2 immunocytokine: preclinical safety studies, phase I clinical trial in patients with solid tumours and expansion into patients with advanced renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

Phase I/II study of the tumour-targeting human monoclonal antibody-cytokine fusion protein L19-TNF in patients with advanced solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

Selective targeted delivery of TNFalpha to tumor blood vessels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

Size comparison between proteins PEGylated with branched and linear poly(ethylene glycol) molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

Folding and stability of a tryptophan-containing mutant of ubiquitin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

Ubiquitin reduces fluid shifts after traumatic brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

Albumin binding to FcRn: distinct from the FcRn-IgG interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

Structural, kinetic, and thermodynamic analysis of the binding of the 40 kDa PEG-interferon-alpha2a and its individual positional isomers to the extracellular domain of the receptor IFNAR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

Selective targeting of tumoral vasculature: Comparison of different formats of an antibody (L19) to the ED-B domain of fibronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

High yield production of recombinant native and modified peptides exemplified by ligands for G-protein coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.519884

Conditions of radioiodination with iodogen as oxidizing agent

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24474690

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Extracellular ubiquitin inhibits the TNF-alpha response to endotoxin in peripheral blood mononuclear cells and regulates endotoxin hyporesponsiveness in critical illness

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24474690

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M113.519884

1 reference

21 August 2017

1 reference

21 August 2017

1 reference