Essential role for the C-terminal noncatalytic region of SHIP in FcgammaRIIB1-mediated inhibitory signaling (Q30305586)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10779347%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Essential role for the C-terminal noncatalytic region of SHIP in FcgammaRIIB1-mediated inhibitory signaling (English)

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6 November 2019

3

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6 November 2019

author name string

M J Aman

1

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6 November 2019

S F Walk

2

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6 November 2019

H P Su

4

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6 November 2019

D J Carver

5

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6 November 2019

K S Ravichandran

6

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6 November 2019

language of work or name

English

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publication date

1 May 2000

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Molecular and Cellular Biology

6 November 2019

published in

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6 November 2019

volume

20

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6 November 2019

issue

10

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6 November 2019

page(s)

3576-3589

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The B cell antigen receptor activates the Akt (protein kinase B)/glycogen synthase kinase-3 signaling pathway via phosphatidylinositol 3-kinase

6 November 2019

cites work

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3 June 2018

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FcgammaRIIb modulation of surface immunoglobulin-induced Akt activation in murine B cells

3 June 2018

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The src homology domain 2-containing inositol phosphatase SHIP forms a ternary complex with Shc and Grb2 in antigen receptor-stimulated B lymphocytes

3 June 2018

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SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival

3 June 2018

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3 June 2018

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A novel spliced form of SH2-containing inositol phosphatase is expressed during myeloid development

3 June 2018

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The SH2 domain-containing inositol 5'-phosphatase (SHIP) recruits the p85 subunit of phosphoinositide 3-kinase during FcgammaRIIb1-mediated inhibition of B cell receptor signaling

3 June 2018

1 reference

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Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells.

3 June 2018

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The inositol phosphatase SHIP inhibits Akt/PKB activation in B cells

3 June 2018

1 reference

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Role of the inositol phosphatase SHIP in B cell receptor-induced Ca2+ oscillatory response.

3 June 2018

1 reference

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The inositol polyphosphate 5-phosphatase ship is a crucial negative regulator of B cell antigen receptor signaling

3 June 2018

1 reference

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Involvement of guanosine triphosphatases and phospholipase C-gamma2 in extracellular signal-regulated kinase, c-Jun NH2-terminal kinase, and p38 mitogen-activated protein kinase activation by the B cell antigen receptor.

3 June 2018

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The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation

3 June 2018

1 reference

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Multiple forms of the SH2-containing inositol phosphatase, SHIP, are generated by C-terminal truncation.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

Signaling from the IL-2 receptor to the nucleus

3 June 2018

1 reference

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SHIP modulates immune receptor responses by regulating membrane association of Btk.

3 June 2018

1 reference

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Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation

3 June 2018

1 reference

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Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals

3 June 2018

1 reference

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Cell lines from kidney proximal tubules of a patient with Lowe syndrome lack OCRL inositol polyphosphate 5-phosphatase and accumulate phosphatidylinositol 4,5-bisphosphate

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling

3 June 2018

1 reference

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Shc interaction with Src homology 2 domain containing inositol phosphatase (SHIP) in vivo requires the Shc-phosphotyrosine binding domain and two specific phosphotyrosines on SHIP

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

The Src homology 2 (SH2) domain of SH2-containing inositol phosphatase (SHIP) is essential for tyrosine phosphorylation of SHIP, its association with Shc, and its induction of apoptosis

3 June 2018

1 reference

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The human SHIP gene is differentially expressed in cell lineages of the bone marrow and blood

3 June 2018

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3 June 2018

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Signaling inositol polyphosphate-5-phosphatase. Characterization of activity and effect of GRB2 association.

3 June 2018

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Growth and differentiation signals regulated by the M-CSF receptor

3 June 2018

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A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

3 June 2018

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The inositol 5'-phosphatase SHIP binds to immunoreceptor signaling motifs and responds to high affinity IgE receptor aggregation

3 June 2018

1 reference

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Cloning and characterization of human SHIP, the 145-kD inositol 5-phosphatase that associates with SHC after cytokine stimulation

3 June 2018

1 reference

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Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.

3 June 2018

1 reference

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Negative signaling in B lymphocytes induces tyrosine phosphorylation of the 145-kDa inositol polyphosphate 5-phosphatase, SHIP.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

Cloning and expression of a human placenta inositol 1,3,4,5-tetrakisphosphate and phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

Activation-induced association of a 145-kDa tyrosine-phosphorylated protein with Shc and Syk in B lymphocytes and macrophages

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

Increased intracellular Ca2+ induces Ca2+ influx in human T lymphocytes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

Erythropoietin stimulates the tyrosine phosphorylation of Shc and its association with Grb2 and a 145-Kd tyrosine phosphorylated protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

Both phosphatidylinositol 3-kinase and phosphatidylinositol 4-kinase products are increased by antigen receptor signaling in B cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways

3 June 2018

1 reference

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B cell antigen receptor stimulation induces formation of a Shc-Grb2 complex containing multiple tyrosine-phosphorylated proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

B cell antigen receptor cross-linking induces phosphorylation of the p21ras oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kDa tyrosine-phosphorylated protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

Multiple Cytokines Stimulate the Binding of a Common 145-Kilodalton Protein to Shc at the Grb2 Recognition Site of Shc

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

Cross-linking of Fc gamma receptor to surface immunoglobulin on B cells provides an inhibitory signal that closes the plasma membrane calcium channel

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

Positive and negative roles of the tyrosine kinase Lyn in B cell function

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85650

Conformational stability, folding, and ligand-binding affinity of single-chain Fv immunoglobulin fragments expressed in Escherichia coli

26 November 2018

1 reference

12 December 2020

Regulation of lymphocyte activation by the cell-surface molecule CD22

1 reference

12 December 2020

Fc receptor off-signal in the B cell involves apoptosis

1 reference

12 December 2020

Negative signaling in B cells causes reduced Ras activity by reducing Shc-Grb2 interactions

1 reference

12 December 2020

Co-ligation of the antigen and Fc receptors gives rise to the selective modulation of intracellular signaling in B cells. Regulation of the association of phosphatidylinositol 3-kinase and inositol 5'-phosphatase with the antigen receptor complex

1 reference

12 December 2020

Divergent roles for Fc receptors and complement in vivo

1 reference

12 December 2020

Growth hormone-induced tyrosine phosphorylation of EGF receptor as an essential element leading to MAP kinase activation and gene expression

1 reference

12 December 2020

Signal TransductionThrough Cytokine Receptors

1 reference

12 December 2020

SHIP recruitment attenuates Fc gamma RIIB-induced B cell apoptosis

1 reference

12 December 2020

10.1128/MCB.20.10.3576-3589.2000

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10779347%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10779347%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

10779347

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10779347%20AND%20SRC:MED&resulttype=core&format=json