Mixing omics: combining genetics and metabolomics to study rheumatic diseases (Q30238656)

12 June 2017

Mixing omics: combining genetics and metabolomics to study rheumatic diseases (English)

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12 June 2017

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Jonas Zierer

2

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Cristina Menni

object named as

Cristina Menni

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1

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Ana M. Valdes

object named as

Ana M Valdes

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3

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Tim D. Spector

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4

object named as

Tim D Spector

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PubMed ID

28148918

12 June 2017

language of work or name

English

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publication date

2 February 2017

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Nature Reviews Rheumatology

12 June 2017

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12 June 2017

13

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12 June 2017

3

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12 June 2017

174-181

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Systems biology: Metabonomics

12 June 2017

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Validity of clinical associations of biomarkers in translational research studies: the case of systemic autoimmune diseases

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Metabolic profiling predicts response to anti-tumor necrosis factor α therapy in patients with rheumatoid arthritis

21 January 2018

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A genome-wide association study of metabolic traits in human urine

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Human metabolic individuality in biomedical and pharmaceutical research

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A genome-wide perspective of genetic variation in human metabolism

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An atlas of genetic influences on human blood metabolites

21 January 2018

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A genome-wide association study of the human metabolome in a community-based cohort

21 January 2018

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Genome-wide association study identifies multiple loci influencing human serum metabolite levels

21 January 2018

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HMDB 3.0--The Human Metabolome Database in 2013

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A positive/negative ion-switching, targeted mass spectrometry-based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue

21 January 2018

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NMR spectroscopy for metabolomics and metabolic profiling.

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Innovation: Metabolomics: the apogee of the omics trilogy

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Application of metabolomics to cardiovascular biomarker and pathway discovery

21 January 2018

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Application of (1)H NMR-based serum metabolomic studies for monitoring female patients with rheumatoid arthritis.

21 January 2018

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Association of urinary metabolites with radiographic progression of knee osteoarthritis in overweight and obese adults: an exploratory study

21 January 2018

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Metabolomic analysis of human plasma reveals that arginine is depleted in knee osteoarthritis patients

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Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate

21 January 2018

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Circulating levels of antioxidant vitamins correlate with better lung function and reduced exposure to ambient pollution

21 January 2018

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Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information

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NMR techniques in biomedical and pharmaceutical analysis

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Targeted metabolomics for biomarker discovery.

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Challenges in mass spectrometry based targeted metabolomics

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Metabolomics in rheumatic diseases: desperately seeking biomarkers

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An introduction to biological NMR spectroscopy

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Quantitative serum nuclear magnetic resonance metabolomics in cardiovascular epidemiology and genetics

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The future of NMR-based metabolomics

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Mass spectrometry strategies in metabolomics

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Mass spectrometry in systems biology: an overview.

21 January 2018

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FiehnLib: Mass Spectral and Retention Index Libraries for Metabolomics Based on Quadrupole and Time-of-Flight Gas Chromatography/Mass Spectrometry

21 January 2018

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Statistical analysis and modeling of mass spectrometry-based metabolomics data

21 January 2018

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Chemometrics in metabolomics--a review in human disease diagnosis

21 January 2018

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Metabolomics in hypertension.

21 January 2018

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Group testing for pathway analysis improves comparability of different microarray datasets.

21 January 2018

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Global functional profiling of gene expression.

21 January 2018

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

21 January 2018

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Causal analysis approaches in Ingenuity Pathway Analysis

21 January 2018

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Database resources of the National Center for Biotechnology Information

21 January 2018

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From genomics to chemical genomics: new developments in KEGG

21 January 2018

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The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases.

21 January 2018

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ChEBI in 2016: Improved services and an expanding collection of metabolites

21 January 2018

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Urinary metabolomic study of systemic lupus erythematosus based on gas chromatography/mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2017.5

Diagnostic properties of metabolic perturbations in rheumatoid arthritis

21 January 2018

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Serum branched-chain amino acid to histidine ratio: a novel metabolomic biomarker of knee osteoarthritis

21 January 2018

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The impact of inflammation on metabolomic profiles in patients with arthritis

21 January 2018

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Metabolic disturbances associated with systemic lupus erythematosus

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Comprehensive metabolome analyses reveal N-acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin

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LC-MS metabolomics of psoriasis patients reveals disease severity-dependent increases in circulating amino acids that are ameliorated by anti-TNFα treatment

21 January 2018

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¹H-NMR-Based Metabolomic Study for Identifying Serum Profiles Associated with the Response to Etanercept in Patients with Rheumatoid Arthritis

21 January 2018

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Estrone/17beta-estradiol conversion to, and tumor necrosis factor inhibition by, estrogen metabolites in synovial cells of patients with rheumatoid arthritis and patients with osteoarthritis

21 January 2018

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Serum metabolic signatures of four types of human arthritis

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Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

21 January 2018

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Genetics of rheumatoid arthritis contributes to biology and drug discovery

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Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility

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Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians

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Comorbidities in rheumatoid arthritis

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Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability.

21 January 2018

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Interleukin 17 inhibits progenitor cells in rheumatoid arthritis cartilage

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Genome-wide association studies with metabolomics

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Autoantibodies in inflammatory arthritis

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Mendelian randomization: genetic anchors for causal inference in epidemiological studies

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Mendelian randomization: prospects, potentials, and limitations

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Association of systemic lupus erythematosus with decreased immunosuppressive potential of the IgG glycome

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Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

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HLA-B27 and human β2-microglobulin affect the gut microbiota of transgenic rats

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Heterogeneity of chronic pain

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Metabolic analysis of knee synovial fluid as a potential diagnostic approach for osteoarthritis.

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Exploration of the serum metabolite signature in patients with rheumatoid arthritis using gas chromatography-mass spectrometry

21 January 2018

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Serum metabolomic profiling in patients with systemic lupus erythematosus by GC/MS.

21 January 2018

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Metabolic changes in psoriatic skin under topical corticosteroid treatment

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Metabolite profiling reveals new insights into the regulation of serum urate in humans

21 January 2018

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Identification of an urinary metabolite profile associated with osteoarthritis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2017.5

Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis

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Applications of NMR spectroscopy to systems biochemistry

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MetaboLights: An Open-Access Database Repository for Metabolomics Data

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Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

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Regulation of apoptosis and inflammatory responses by insulin-like growth factor binding protein 3 in fibroblast-like synoviocytes and experimental animal models of rheumatoid arthritis

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¹H NMR-based metabolomic study of metabolic profiling for systemic lupus erythematosus

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A metabolic profiling analysis of symptomatic gout in human serum and urine using high performance liquid chromatography-diode array detector technique

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31 March 2020

Identifiers

DOI

10.1038/NRRHEUM.2017.5

1 reference

PubMed ID

28148918

Dimensions Publication ID

12 June 2017

0 references

1 reference

PubMed ID

28148918