An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors (Q30159709)

8 June 2017

An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors (English)

1 reference

8 June 2017

Carly Huitema

5

0 references

Lindsay D. Eltis

object named as

Lindsay D Eltis

7

0 references

John Christopher Vederas

object named as

John C Vederas

8

0 references

author name string

Jiang Yin

1

1 reference

8 June 2017

Maia M Cherney

2

1 reference

8 June 2017

Ernst M Bergmann

3

1 reference

8 June 2017

Jianmin Zhang

4

1 reference

8 June 2017

Hanna Pettersson

6

1 reference

8 June 2017

Michael N G James

9

1 reference

8 June 2017

language of work or name

English

0 references

publication date

7 July 2006

1 reference

Journal of Molecular Biology

8 June 2017

1 reference

8 June 2017

361

1 reference

8 June 2017

4

1 reference

8 June 2017

673-686

1 reference

The refined crystal structure of the 3C gene product from hepatitis A virus: specific proteinase activity and RNA recognition

8 June 2017

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

Mechanisms of sulfanyl (RS) migrations: synthesis of heterocycles

1 reference

12 December 2020

In vitro and ex vivo inhibition of hepatitis A virus 3C proteinase by a peptidyl monofluoromethyl ketone.

1 reference

12 December 2020

Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs

1 reference

12 December 2020

The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

1 reference

12 December 2020

Cysteine proteases of positive strand RNA viruses and chymotrypsin-like serine proteases. A distinct protein superfamily with a common structural fold

1 reference

12 December 2020

LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

1 reference

12 December 2020

Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes

1 reference

12 December 2020

Crystal structure of foot-and-mouth disease virus 3C protease. New insights into catalytic mechanism and cleavage specificity

1 reference

12 December 2020

Crystal structures of the main peptidase from the SARS coronavirus inhibited by a substrate-like aza-peptide epoxide.

1 reference

12 December 2020

Proteolytic processing of picornaviral polyprotein

1 reference

12 December 2020

The CCP4 suite: programs for protein crystallography

1 reference

12 December 2020

Viral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implications

1 reference

12 December 2020

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

1 reference

12 December 2020

Efficient anisotropic refinement of macromolecular structures using FFT

1 reference

12 December 2020

Inhibition of serine proteases by peptidyl fluoromethyl ketones

1 reference

12 December 2020

Picornaviral 3C cysteine proteinases have a fold similar to chymotrypsin-like serine proteinases

1 reference

12 December 2020

Selective five- and six-membered cyclic amine syntheses via capture of episulfonium ions

1 reference

12 December 2020

Economic costs of the foot and mouth disease outbreak in the United Kingdom in 2001.

1 reference

12 December 2020

Evidence for hemiketals as intermediates in the inactivation of serine proteinases with halomethyl ketones

1 reference

12 December 2020

Synthesis and properties of peptidyl derivatives of arginylfluoromethanes

1 reference

12 December 2020

Synthesis and evaluation of keto-glutamine analogues as inhibitors of hepatitis A virus 3C proteinase

1 reference

12 December 2020

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

1 reference

12 December 2020

Chloroketone hydrolysis by chymotrypsin and N-methylhistidyl-57-chymotrypsin: implications for the mechanism of chymotrypsin inactivation by chloroketones

1 reference

12 December 2020

Hepatitis A virus 3C proteinase substrate specificity

1 reference

12 December 2020

Binding of chloromethyl ketone substrate analogues to crystalline papain

1 reference

12 December 2020

An x-ray crystallographic study of the binding of peptide chloromethyl ketone inhibitors to subtilisin BPN'

1 reference

12 December 2020

X-ray structures and anionotropic rearrangements of Di-tert-butyl-substituted thiiranium and thiirenium ions. A structure-reactivity relationship

1 reference

12 December 2020

Three-dimensional structure of chymotrypsin inactivated with (2S)-N-acetyl-L-alanyl-L-phenylalanyl alpha-chloroethane: implications for the mechanism of inactivation of serine proteases by chloroketones

1 reference

12 December 2020

Crystal structure of an inhibitor complex of the 3C proteinase from hepatitis A virus (HAV) and implications for the polyprotein processing in HAV

1 reference

12 December 2020

Dual modes of modification of hepatitis A virus 3C protease by a serine-derived beta-lactone: selective crystallization and formation of a functional catalytic triad in the active site

1 reference

12 December 2020

On the size of the active site in proteases. I. Papain

1 reference

12 December 2020

10.1016/J.JMB.2006.06.047

Identifiers

DOI

1 reference

8 June 2017

0 references

1 reference