Structure, dynamics, and Hck interaction of full-length HIV-1 Nef. (Q30155826)

16 October 2017

Structure, dynamics, and Hck interaction of full-length HIV-1 Nef. (English)

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16 October 2017

4

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16 October 2017

Jinwon Jung

1

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author name string

In-Ja L Byeon

series ordinal

2

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16 October 2017

Jinwoo Ahn

series ordinal

3

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16 October 2017

language of work or name

English

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publication date

1 March 2011

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16 October 2017

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16 October 2017

79

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16 October 2017

5

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16 October 2017

1609-1622

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Crystal Structure of the Src Family Kinase Hck SH3-SH2 Linker Regulatory Region Supports an SH3-dominant Activation Mechanism

16 October 2017

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Pseudo-merohedral twinning and noncrystallographic symmetry in orthorhombic crystals of SIVmac239 Nef core domain bound to different-length TCRζ fragments

3 June 2018

1 reference

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HIV-1 Nef: at the crossroads

3 June 2018

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HIV-1 accessory proteins--ensuring viral survival in a hostile environment

3 June 2018

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Solution structure of a Hck SH3 domain ligand complex reveals novel interaction modes

3 June 2018

1 reference

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HIV-1 Nef selectively activates Src family kinases Hck, Lyn, and c-Src through direct SH3 domain interaction

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Human immunodeficiency virus type 1 Nef: adapting to intracellular trafficking pathways

3 June 2018

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Human immunodeficiency virus type 1 Nef domains required for disruption of major histocompatibility complex class I trafficking are also necessary for coprecipitation of Nef with HLA-A2.

3 June 2018

1 reference

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Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells

3 June 2018

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The Xplor-NIH NMR molecular structure determination package

3 June 2018

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SH3-SH2 domain orientation in Src kinases: NMR studies of Fyn.

3 June 2018

1 reference

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Dynamic coupling between the SH2 and SH3 domains of c-Src and Hck underlies their inactivation by C-terminal tyrosine phosphorylation

3 June 2018

1 reference

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Interactions of HIV-1 nef with the mu subunits of adaptor protein complexes 1, 2, and 3: role of the dileucine-based sorting motif

3 June 2018

1 reference

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HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes

3 June 2018

1 reference

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Interactions of HIV-1 NEF with cellular signal transducing proteins

3 June 2018

1 reference

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Nef-induced major histocompatibility complex class I down-regulation is functionally dissociated from its virion incorporation, enhancement of viral infectivity, and CD4 down-regulation

3 June 2018

1 reference

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Simian immunodeficiency virus and human immunodeficiency virus type 1 nef proteins show distinct patterns and mechanisms of Src kinase activation

3 June 2018

1 reference

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Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Measurement of J and dipolar couplings from simplified two-dimensional NMR spectra

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Solution structure of the human Hck SH3 domain and identification of its ligand binding site

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Determining the structures of large proteins and protein complexes by NMR.

3 June 2018

1 reference

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Lymphoproliferative immune function in the Sydney Blood Bank Cohort, infected with natural nef/long terminal repeat mutants, and in other long-term survivors of transfusion-acquired HIV-1 infection.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Refined solution structure and backbone dynamics of HIV-1 Nef.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Solution structure of a polypeptide from the N terminus of the HIV protein Nef

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Crystal structure of the Src family tyrosine kinase Hck

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects

3 June 2018

1 reference

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Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

3 June 2018

1 reference

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Purification and characterization of human immunodeficiency virus type 1 nef gene product expressed by a recombinant baculovirus

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076547

Domain assembly, surface accessibility and sequence conservation in full length HIV-1 Nef.

3 June 2018

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https://api.crossref.org/works/10.1002%2FPROT.22986

Localizing the NADP+ binding site on the MurB enzyme by NMR.

21 January 2018

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Sequence-dependent correction of random coil NMR chemical shifts

21 January 2018

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NMR: prediction of molecular alignment from structure using the PALES software.

21 January 2018

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A novel interactive tool for rigid-body modeling of multi-domain macromolecules using residual dipolar couplings.

21 January 2018

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Long-range motional restrictions in a multidomain zinc-finger protein from anisotropic tumbling.

21 January 2018

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The tyrosine binding pocket in the adaptor protein 1 (AP-1) mu1 subunit is necessary for Nef to recruit AP-1 to the major histocompatibility complex class I cytoplasmic tail

21 January 2018

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HIV-1 Nef membrane association depends on charge, curvature, composition and sequence.

21 January 2018

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TROSY-type Triple-Resonance Experiments for Sequential NMR Assignments of Large Proteins

21 January 2018

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Rotational diffusion anisotropy of proteins from simultaneous analysis of 15N and 13C alpha nuclear spin relaxation

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21365684

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/PROT.22986

1 reference

release_kdfmafctvrhutcbsbnvwfjnobe

16 October 2017

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Fatcat

https://api.fatcat.wiki/v0/release/kdfmafctvrhutcbsbnvwfjnobe

mapped directly with Wikidata item

24 November 2022

based on heuristic

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16 October 2017

PubMed publication ID

21365684

1 reference