Polypeptide release factors and stop codon recognition in the apicoplast and mitochondrion of Plasmodium falciparum (Q30039559)

peptide chain release factor 2

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peptide chain release factor 1

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peptide chain release factor 1

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peptidyl-tRNA hydrolase ICT1

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peptidyl-tRNA hydrolase ICT1

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Suniti Vaishya

1

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Vikash Kumar

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Ankit Gupta

3

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Mohammad Imran Siddiqi

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Saman Habib

Ribosome rescue and translation termination at non-standard stop codons by ICT1 in mammalian mitochondria.

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language of work or name

English

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publication date

June 2016

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published in

Molecular Microbiology

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volume

100

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issue

6

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page(s)

1080-95

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cites work

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Mutations in C12orf65 in patients with encephalomyopathy and a mitochondrial translation defect

21 January 2018

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Overcoming codon bias: a method for high-level overexpression of Plasmodium and other AT-rich parasite genes in Escherichia coli.

21 January 2018

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Interaction of apicoplast-encoded elongation factor (EF) EF-Tu with nuclear-encoded EF-Ts mediates translation in the Plasmodiumfalciparum plastid

21 January 2018

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Plasmodium falciparum apicoplast drugs: targets or off-targets?

21 January 2018

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Escherichia coli YaeJ protein mediates a novel ribosome-rescue pathway distinct from SsrA- and ArfA-mediated pathways.

21 January 2018

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The apicoplast of Plasmodium falciparum is translationally active.

21 January 2018

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Computational method to predict mitochondrially imported proteins and their targeting sequences

21 January 2018

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Apicoplast translation, transcription and genome replication: targets for antimalarial antibiotics

21 January 2018

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Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum

21 January 2018

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Peptidyl-tRNA hydrolase and its critical role in protein biosynthesis

21 January 2018

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Evidence for a Single Origin of the 35 kb Plastid DNA in Apicomplexans.

21 January 2018

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Evolution and diversification of the organellar release factor family.

21 January 2018

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Homologies between the contiguous and fragmented rRNAs of the two Plasmodium falciparum extrachromosomal DNAs are limited to core sequences

21 January 2018

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The fragmented mitochondrial ribosomal RNAs of Plasmodium falciparum.

21 January 2018

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A plastid organelle as a drug target in apicomplexan parasites.

21 January 2018

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Histidine 197 in release factor 1 is essential for a site binding and peptide release

21 January 2018

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Dissecting apicoplast targeting in the malaria parasite Plasmodium falciparum

21 January 2018

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Release factor RF3 in E.coli accelerates the dissociation of release factors RF1 and RF2 from the ribosome in a GTP-dependent manner

21 January 2018

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Ultrasensitive fluorescence-based detection of nascent proteins in gels

21 January 2018

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Ycf93 (Orf105), a small apicoplast-encoded membrane protein in the relict plastid of the malaria parasite Plasmodium falciparum that is conserved in Apicomplexa

21 January 2018

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The effects of anti-bacterials on the malaria parasite Plasmodium falciparum.

21 January 2018

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Localization and characterization of the gene encoding release factor RF3 in Escherichia coli

21 January 2018

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Recycling factors for ribosome disassembly in the apicoplast and mitochondrion of Plasmodium falciparum

21 January 2018

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The effect of fusidic acid on Plasmodium falciparum elongation factor G (EF-G).

21 January 2018

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Reduced ribosomes of the apicoplast and mitochondrion of Plasmodium spp. and predicted interactions with antibiotics

21 January 2018

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Targeting and function of proteins mediating translation initiation in organelles of Plasmodium falciparum

21 January 2018

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YaeJ is a novel ribosome-associated protein in Escherichia coli that can hydrolyze peptidyl-tRNA on stalled ribosomes

21 January 2018

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Kinetics of stop codon recognition by release factor 1.

21 January 2018

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Single amino acid substitution in prokaryote polypeptide release factor 2 permits it to terminate translation at all three stop codons

21 January 2018

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Protein translation in Plasmodium parasites.

21 January 2018

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Characterization of two malaria parasite organelle translation elongation factor G proteins: the likely targets of the anti-malarial fusidic acid

21 January 2018

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Conditionally lethal and recessive UGA-suppressor mutations in the prfB gene encoding peptide chain release factor 2 of Escherichia coli

21 January 2018

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Release of ribosome-bound ribosome recycling factor by elongation factor G.

21 January 2018

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Structure of the Escherichia coli ribosomal termination complex with release factor 2

21 January 2018

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Identification of residues required for stalled-ribosome rescue in the codon-independent release factor YaeJ

21 January 2018

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Structural aspects of translation termination on the ribosome

21 January 2018

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Crystal structure of a translation termination complex formed with release factor RF2

21 January 2018

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PDBsum: summaries and analyses of PDB structures

21 January 2018

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PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

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Structural basis for translation termination on the 70S ribosome

21 January 2018

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Phylogenetic distribution of translational GTPases in bacteria

21 January 2018

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Mitochondrial drug targets in apicomplexan parasites.

21 January 2018

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Identification of the prfC gene, which encodes peptide-chain-release factor 3 of Escherichia coli

21 January 2018

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Stop codon recognition and interactions with peptide release factor RF3 of truncated and chimeric RF1 and RF2 from Escherichia coli.

21 January 2018

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Targeting the mitochondrial electron transport chain of Plasmodium falciparum: new strategies towards the development of improved antimalarials for the elimination era.

21 January 2018

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N-terminal labeling of proteins using initiator tRNA.

21 January 2018

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Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon

21 January 2018

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UCSF Chimera--a visualization system for exploratory research and analysis

21 January 2018

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Mitochondrial translation in absence of local tRNA aminoacylation and methionyl tRNA Met formylation in Apicomplexa

21 January 2018

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Predicted and observed alleles of Plasmodium falciparum merozoite surface protein-1 (MSP-1), a potential malaria vaccine antigen

21 January 2018

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DNA organization by the apicoplast-targeted bacterial histone-like protein of Plasmodium falciparum

21 January 2018

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Interactions of the release factor RF1 with the ribosome as revealed by cryo-EM.

21 January 2018

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A cryo-electron microscopic study of ribosome-bound termination factor RF2

21 January 2018

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A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome

21 January 2018

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Comparative protein modelling by satisfaction of spatial restraints

21 January 2018

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Plasmodium falciparum mitochondria import tRNAs along with an active phenylalanyl-tRNA synthetase

21 January 2018

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The metabolic roles of the endosymbiotic organelles of Toxoplasma and Plasmodium spp

21 January 2018

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Identification, developmental regulation, and response to heat shock of two antigenically related forms of a major nuclear envelope protein in Drosophila embryos: application of an improved method for affinity purification of antibodies using polype

21 January 2018

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mtRF1a is a human mitochondrial translation release factor decoding the major termination codons UAA and UAG

21 January 2018

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Localization of organellar proteins in Plasmodium falciparum using a novel set of transfection vectors and a new immunofluorescence fixation method

21 January 2018

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Human malaria parasites in continuous culture

21 January 2018

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Thermodynamic and kinetic insights into stop codon recognition by release factor 1.

21 January 2018

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A model for how ribosomal release factors induce peptidyl-tRNA cleavage in termination of protein synthesis.

21 January 2018

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Bacterial polypeptide release factor RF2 is structurally distinct from eukaryotic eRF1

21 January 2018

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Protein trafficking to the plastid of Plasmodium falciparum is via the secretory pathway

21 January 2018

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Insights into Translational Termination from the Structure of RF2 Bound to the Ribosome

21 January 2018

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Progress with parasite plastids

21 January 2018

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Deciphering apicoplast targeting signals--feature extraction from nuclear-encoded precursors of Plasmodium falciparum apicoplast proteins

21 January 2018

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