Signal-transducer and activator of transcription protein at 92E Dmel_CG4257 (Q29820685)

STAT transcription factor, DNA-binding, N-terminal

1 reference

transcription factor STAT

1 reference

STAT transcription factor, coiled coil

1 reference

SH2 domain superfamily

1 reference

STAT transcription factor, N-terminal domain superfamily

1 reference

STAT transcription factor, protein interaction, protein family

1 reference

SH2 domain, protein family

1 reference

STAT transcription factor, DNA-binding domain, protein family

1 reference

STAT transcription factor, all-alpha domain, protein family

1 reference

DNA-binding transcription activator activity, RNA polymerase II-specific

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

1 reference

9 May 2019

Drosophila linker histone H1 coordinates STAT-dependent organization of heterochromatin and suppresses tumorigenesis caused by hyperactive JAK-STAT signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

cytokine receptor binding

1 reference

9 May 2019

Mechanisms of JAK/STAT pathway negative regulation by the short coreceptor Eye Transformer/Latran.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

DNA-binding transcription factor activity

IPI

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

7 references

8 April 2019

The roles of JAK/STAT signaling in Drosophila immune responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

8 April 2019

Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

8 April 2019

Transcriptional regulation of the Drosophila raf proto-oncogene by Drosophila STAT during development and in immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

8 April 2019

Polarized subcellular localization of Jak/STAT components is required for efficient signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

8 April 2019

Role of Scrib and Dlg in anterior-posterior patterning of the follicular epithelium during Drosophila oogenesis.

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

3 references

9 May 2019

The roles of JAK/STAT signaling in Drosophila immune responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

cytoplasmic side of apical plasma membrane

1 reference

9 May 2019

Polarized subcellular localization of Jak/STAT components is required for efficient signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

8 references

9 May 2019

The roles of JAK/STAT signaling in Drosophila immune responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

Polarized subcellular localization of Jak/STAT components is required for efficient signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

Transcriptional regulation of the Drosophila raf proto-oncogene by Drosophila STAT during development and in immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

Role of Scrib and Dlg in anterior-posterior patterning of the follicular epithelium during Drosophila oogenesis.

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

Polarized subcellular localization of Jak/STAT components is required for efficient signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

positive regulation of defense response to virus by host

biological process

1 reference

9 May 2019

A Novel System for the Launch of Alphavirus RNA Synthesis Reveals a Role for the Imd Pathway in Arthropod Antiviral Response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

transcription, DNA-templated

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24151&geneProductId=UniProtKB:Q24151

regulation of transcription, DNA-templated

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

transcription by RNA polymerase II

1 reference

16 July 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24151&geneProductId=UniProtKB:Q24151

1 reference

8 April 2019

Transcriptional regulation of the Drosophila raf proto-oncogene by Drosophila STAT during development and in immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

The roles of JAK/STAT signaling in Drosophila immune responses

humoral immune response

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

receptor signaling pathway via JAK-STAT

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24151&geneProductId=UniProtKB:Q24151

24 April 2018

The fertile field of Drosophila Jak/STAT signalling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24151&geneProductId=UniProtKB:Q24151

24 April 2018

Eye transformer is a negative regulator of Drosophila JAK/STAT signaling.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24151&geneProductId=UniProtKB:Q24151

multicellular organism development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

border follicle cell migration

3 references

5 June 2018

The fertile field of Drosophila Jak/STAT signalling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24151&geneProductId=UniProtKB:Q24151

5 June 2018

Paracrine signaling through the JAK/STAT pathway activates invasive behavior of ovarian epithelial cells in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24151&geneProductId=UniProtKB:Q24151

5 June 2018

Border-cell migration requires integration of spatial and temporal signals by the BTB protein Abrupt

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24151&geneProductId=UniProtKB:Q24151

blastoderm segmentation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

Characterisation of Upd2, a Drosophila JAK/STAT pathway ligand.

segment specification

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

nervous system development

1 reference

9 May 2019

Patterns and functions of STAT activation during Drosophila embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

open tracheal system development

1 reference

9 May 2019

Patterns and functions of STAT activation during Drosophila embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

epithelial cell fate determination, open tracheal system

1 reference

16 July 2018

Branching morphogenesis of the Drosophila tracheal system.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24151&geneProductId=UniProtKB:Q24151

eye-antennal disc morphogenesis

1 reference

9 May 2019

JAK/STAT signaling promotes regional specification by negatively regulating wingless expression in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

imaginal disc-derived wing morphogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

larval somatic muscle development

NAS

1 reference

9 May 2019

A systematic analysis of Tinman function reveals Eya and JAK-STAT signaling as essential regulators of muscle development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

sex-determination system

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

primary sex determination

NAS

1 reference

9 May 2019

The JAK/STAT signaling pathway is required for the initial choice of sexual identity in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

1 reference

9 May 2019

Cytokine signaling through the JAK/STAT pathway is required for long-term memory in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

positive regulation of cell population proliferation

1 reference

9 May 2019

Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

1 reference

9 May 2019

Control of stem cell self-renewal in Drosophila spermatogenesis by JAK-STAT signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

stem cell population maintenance

1 reference

9 May 2019

Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

ovarian follicle cell stalk formation

1 reference

9 May 2019

A Notch/Delta-dependent relay mechanism establishes anterior-posterior polarity in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

germ-line stem cell population maintenance

1 reference

9 May 2019

Regeneration of male germline stem cells by spermatogonial dedifferentiation in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

oocyte localization involved in germarium-derived egg chamber formation

1 reference

9 May 2019

A Notch/Delta-dependent relay mechanism establishes anterior-posterior polarity in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

positive regulation of heterochromatin assembly

1 reference

9 May 2019

Drosophila linker histone H1 coordinates STAT-dependent organization of heterochromatin and suppresses tumorigenesis caused by hyperactive JAK-STAT signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

somatic stem cell population maintenance

1 reference

9 May 2019

Competitiveness for the niche and mutual dependence of the germline and somatic stem cells in the Drosophila testis are regulated by the JAK/STAT signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis

hemocyte proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

germ-line stem cell division

1 reference

9 May 2019

The stem-cell niche theory: lessons from flies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

Dedifferentiating spermatogonia outcompete somatic stem cells for niche occupancy in the Drosophila testis

cell dedifferentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

positive regulation of transcription by RNA polymerase II

IEP

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

somatic stem cell division

1 reference

9 May 2019

The stem-cell niche theory: lessons from flies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

3 references

5 June 2018

The fertile field of Drosophila Jak/STAT signalling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24151&geneProductId=UniProtKB:Q24151

5 June 2018

A Notch/Delta-dependent relay mechanism establishes anterior-posterior polarity in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24151&geneProductId=UniProtKB:Q24151

5 June 2018

The Drosophila STAT protein, stat92E, regulates follicle cell differentiation during oogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24151&geneProductId=UniProtKB:Q24151

compound eye development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

cellular response to lipopolysaccharide

1 reference

9 May 2019

Transcriptional regulation of the Drosophila raf proto-oncogene by Drosophila STAT during development and in immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

cellular response to X-ray

1 reference

9 May 2019

STAT92E is a positive regulator of Drosophila inhibitor of apoptosis 1 (DIAP/1) and protects against radiation-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

negative regulation of stem cell differentiation

1 reference

9 May 2019

Epigenetic regulator Lid maintains germline stem cells through regulating JAK-STAT signaling pathway activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

receptor signaling pathway via JAK-STAT

NAS

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

8 April 2019

Eye transformer is a negative regulator of Drosophila JAK/STAT signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

8 April 2019

Identification of JAK/STAT signalling components by genome-wide RNA interference.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling

wing disc morphogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

The TEAD family transcription factor Scalloped regulates blood progenitor maintenance and proliferation in Drosophila through PDGF/VEGFR receptor (Pvr) signaling

lymph gland development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

receptor signaling pathway via JAK-STAT

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

Eye transformer is a negative regulator of Drosophila JAK/STAT signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

Identification of JAK/STAT signalling components by genome-wide RNA interference.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

regulation of cell population proliferation

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151

positive regulation of transcription by RNA polymerase II

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24151